Publications

Kümmerle A, Schmid C, Bernhard S, Kande V, Mutombo W, Ilunga M, Lumpungu I, Mutanda S, Nganzobo P, Tete D.N, Kisala M, Burri C, Blesson S, Valverde Mordt O. Effectiveness of Nifurtimox Eflornithine Combination Therapy (NECT) in T. b. gambiense second stage sleeping sickness patients in the Democratic Republic of Congo: report from a field study. PLoS Negl Trop Dis. 2021;15(11):e0009903. DOI: 10.1371/journal.pntd.0009903

Ticlla M.R, Hella J, Hiza H, Sasamalo M, Mhimbira F, Rutaihwa L.K, Droz S, Schaller S, Reither K, Hilty M, Comas I, Beisel C, Schmid C.D, Fenner L, Gagneux S. The sputum microbiome in pulmonary tuberculosis and its association with disease manifestations: a cross-sectional study. Front Microbiol. 2021;12:633396. DOI: 10.3389/fmicb.2021.633396

Kümmerle A, Schmid C, Kande V, Mutombo W, Ilunga M, Lumpungu I, Mutanda S, Nganzobo P, Ngolo D, Kisala M, Valverde Mordt O. Prescription of concomitant medications in patients treated with nifurtimox eflornithine combination therapy (NECT) for T.b. gambiense second stage sleeping sickness in the Democratic Republic of the Congo. PLoS Negl Trop Dis. 2020;14(1):e0008028. DOI: 10.1371/journal.pntd.0008028

Manser M, Sater M.R, Schmid C.D, Noreen F, Murbach M, Kuster N, Schuermann D, Schar P. ELF-MF exposure affects the robustness of epigenetic programming during granulopoiesis. Sci Rep. 2017;7:43345. DOI: 10.1038/srep43345

Küpfer I, Schmid C, Allan M, Edielu A, Haary E.P, Kakembo A, Kibona S, Blum J, Burri C. Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage rhodesiense sleeping sickness. PLoS Negl Trop Dis. 2012;6(8):e1695. DOI: 10.1371/journal.pntd.0001695

Schmid C, Kümmerle A, Blum J, Ghabri S, Kande V, Mutombo W, Ilunga M, Lumpungu I, Mutanda S, Nganzobo P, Tete D, Mubwa N, Kisala M, Blésson S, Mordt O.V. In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for T.b. gambiense sleeping sickness. PLoS Negl Trop Dis. 2012;6(11):e1920. DOI: 10.1371/journal.pntd.0001920

Mordt O.V, Schmid C, Kande V, Mutombo W, Ilunga M, Lumpungu I, Mutanda S, Tete D, Nganzobo P, Mubwa N, Kisala M, Blum J, Blésson S, Wourgaft N.S. A multicenter, open label, phase III study of therapeutic use of the co-administration of nifurtimox and eflornithine (NECT) for human African trypanosomiasis (NECT field): safety profile in children during initial hospitalization. Trop Med Int Health, 2011;16(Suppl. 1):68-68

Blum J, Schmid C, Burri C, Hatz C, Olson C, Fungula B, Kazumba L, Mangoni P, Mbo F, Deo K, Mpanya A, Dala A, Franco J.R, Pohlig G, Zellweger M.J. Cardiac alterations in human African trypanosomiasis (T.b. gambiense) with respect to the disease stage and antiparasitic treatment. PLoS Negl Trop Dis. 2009;3(2):e383. DOI: 10.1371/journal.pntd.0000383

Priotto G, Kasparian S, Mutombo W, Ngouama D, Ghorashian S, Arnold U, Ghabri S, Baudin E, Buard V, Kazadi-Kyanza S, Ilunga M, Mutangala W, Pohlig G, Schmid C, Karunakara U, Torreele E, Kande V. Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial. Lancet. 2009;374(9683):56-64. DOI: 10.1016/S0140-6736(09)61117-X

Blum J.A, Schmid C, Hatz C, Kazumba L, Mangoni P, Rutishauser J, la Torre A, Burri C. Sleeping glands? - The role of endocrine disorders in sleeping sickness (T.b. gambiense Human African Trypanosomiasis). Acta Trop. 2007;104(1):16-24. DOI: 10.1016/j.actatropica.2007.07.004

Eperon G, Schmid C, Loutan L, Chappuis F. Clinical presentation and treatment outcome of sleeping sickness in Sudanese pre-school children. Acta Trop. 2007;101(1):31-39

Blum J, Schmid C, Burri C. Clinical aspects of 2541 patients with second stage human African trypanosomiasis. Acta Trop. 2006;97(1):55-64

Schmid C, Richer M, Bilenge C.M, Josenando T, Chappuis F, Manthelot C.R, Nangouma A, Doua F, Asumu P.N, Simarro P.P, Burri C. Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (IMPAMEL II). J Infect Dis. 2005;191(11):1922-1931

Kamazni Atindehou K, Schmid C, Brun R, Koné M.W, Traore D. Antitrypanosomal and antiplasmodial activity of medicinal plants from Côte d' Ivoire. J Ethnopharmacol. 2004;90(2-3):221-227

Schmid Caecilia. 10-day melarsoprol treatment of "Trypanosoma brucei gambiense" sleeping sickness: from efficacy to effectiveness. Basel: Univ. Basel, 2004. Doctoral Thesis, University of Basel, Faculty of Science DOI: 10.5451/unibas-003507965

Louis F.J, Keiser J, Simarro P.P, Schmid C, Jannin J. Eflornithine in the treatment of African trypanosomiasis. Méd Trop (Mars. ). 2003;63:559-563

Ankli A, Heinrich M, Bork P, Wolfram L, Bauerfeind P, Brun R, Schmid C, Weiss C, Bruggisser R, Gertsch J, Wasescha M, Sticher O. Yucatec Mayan medicinal plants: evaluation based on indigenous uses. J Ethnopharmacol. 2002;79(1):43-52

Brun R, Schumacher R, Schmid C, Kunz C, Burri C. The phenomenon of treatment failures in human African trypanosomiasis. Trop Med Int Health. 2001;6(11):906-914

Mäser P, Vogel D, Schmid C, Raez B, Kaminsky R. Identification and characterization of trypanocides by functional expression of an adenosine transporter from Trypanosoma brucei in yeast. J Mol Med. 2001;79(2-3):121-127

Matovu E, Enyaru J.C, Legros D, Schmid C, Seebeck T, Kaminsky R. Melarsoprol refractory T. b. gambiense from Omugo, north-western Uganda. Trop Med Int Health. 2001;6(5):407-411

El Rayah I.E, Kaminsky R, Schmid C, El Malik K.H. Drug resistance in Sudanese Trypanosoma evansi. Vet Parasitol. 1999;80(4):281-287

Enyaru J.C.K, Matovu E, Akol M, Sebikali C, Kyambadde J, Schmid C, Brun R, Kaminsky R, Ogwal L.M, Kansiime F. Parasitological detection of Trypanosoma brucei gambiense in serologically negative sleeping-sickness suspects from north-western Uganda. Ann Trop Med Parasitol. 1998;92(8):845-850

Kaminsky R, Schmid C, Lun Z.R. Susceptibility of dyskinetoplastic Trypanosoma evansi and T. equiperdum to isometamidium chloride. Parasitol Res. 1997;83(8):816-818

Matovu E, Iten M, Enyaru J.C.K, Schmid C, Lubega G.W, Brun R, Kaminsky R. Susceptibility of Ugandan Trypanosoma brucei rhodesiense isolated from man and animal reservoirs to diminazene, isometamidium and melarsoprol. Trop Med Int Health. 1997;2(1):13-18

Kaminsky R, Schmid C, Brun R. An "in vitro selectivity index" for evaluation of cytotoxicity of antitrypanosomal compounds. In Vitro Toxicol. 1996;9(3):315-324

Kaminsky R, Schmid C, Grether Y, Holy A, DeClercq E, Naesens L, Brun R. (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine [(S)-HPMPA]: a purine analogue with trypanocidal activity in vitro and in vivo. Trop Med Int Health. 1996;1(2):255-263

Obexer W, Schmid C, Barbe J, Galy J.P, Brun R. Activity and structure relationship of acridine derivatives against African trypanosomes. Trop Med Parasitol. 1995;46(1):49-53

Obexer W, Schmid C, Brun R. A novel in vitro screening assay for trypanocidal activity using the fluorescent dye BCECF-AM. Trop Med Parasitol. 1995;46(1):45-48