Electrophysiological markers and predictors of the disease course in primary progressive multiple sclerosis (Publications)
BACKGROUND: Currently no valid surrogate marker exists for primary progressive multiple sclerosis (PPMS). OBJECTIVE: Our aim was to prospectively investigate multimodal evoked potentials (EPs) as mark
Glycerol-3-phosphate acyltransferases gat1p and gat2p are microsomal phosphoproteins with differential contributions to polarized cell growth (Publications)
Glycerol-3-phosphate acyltransferase (GPAT) catalyzes the initial step in the synthesis of all glycerolipids. It is the committed and rate-limiting step and is redundant in Saccharomyces cerevisiae, m
Pseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD (Publications)
The enzymes of the non-mevalonate pathway for isoprenoid biosynthesis have been identified as attractive targets with novel modes of action for the development of herbicides for crop protection and ag
Luftverschmutzung und Gesundheit - Optionen in der klinischen Beratung (Publications)
While air quality is usually an environmental condition patients can little do about, there are a few options and decisions that modify the personal exposure and risk. Location - in particular the res
Effect of ibandronate on spontaneous osteonecrosis of the knee: a randomized, double-blind, placebo-controlled trial (Publications)
Based on this double-blind, placebo-controlled study, ibandronate has no beneficial effect on clinical and radiological outcome in patients with spontaneous osteonecrosis of the knee over and above an
Reasons for false-positive lipoarabinomannan ELISA results in a Tanzanian population [Short communication] (Publications)
Lipoarabinomannan (LAM), a cell wall component of mycobacteria, can be detected in the urine of tuberculosis (TB) patients. Advantages of this diagnostic include the ease of sample collection and test
Use of B-type natriuretic peptide for the management of women with dyspnea (Publications)
In studies with predominately male patients, B-type natriuretic peptide (BNP) levels have been shown to be helpful in the evaluation and management of patients who present with acute dyspnea. The effe
The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer) (Publications)
Praziquantel has been the mainstay of schistosomiasis control since 1984 and widely distributed since 2006 through 'preventive chemotherapy' programmes to school-aged children or at-risk populations.
Activity of diimidazoline amides against <em>African trypanosomiasis</em> (Publications)
We identified several diimidazoline mono- and diamides that were as potent as pentamidine against Trypanosoma brucei rhodesiense in vitro. All of these were also less cytotoxic than pentamidine, but n