Bicyclic amido compounds with antiprotozoal activity (Publications)
Aroyl derivatives of 2-aminobicyclo-octanes and 2-azabicyclo-nonanes have been synthesized and tested for their activities against the causative organisms of East African trypanosomiasis and malaria t
Variation in survival after diagnosis of breast cancer in Switzerland (Publications)
BACKGROUND: Survival after diagnosis of cancer is a key criterion for cancer control. Major survival differences between time periods and countries have been reported by the EUROCARE studies. We inves
Risk factors for infections with<em> Norovirus </em>gastrointestinal illness in Switzerland (Publications)
Viral infections, particularly those caused by noroviruses (NV, genus Norovirus), are the most common cause of community-acquired gastroenteritis in Europe, with respect to both endemic and epidemic o
Predicting outcomes in critically ill patients with acute kidney injury undergoing intermittent hemodialysis - A retrospective cohort analysis (Publications)
Purpose: Despite advances in the management of critically ill patients with acute kidney injury (AKI), the prognosis is poor. The evidence base on risk factors for poor outcomes in these patients is s
Synthesis and antiplasmodial activity of new N-[3-(4-{3-[(7-chloroquinolin-4-yl)amino]propyl}piperazin-1-yl)propyl]carboxamides (Publications)
The parallel acylation of N-{3-[4-(3-aminopropyl)piperazin-1-yl]propyl}-7-chloroquinolin-4-amine with polymer-bound carboxylic acids opened straightforward access to novel aminoquinolines with activit
Rapid propagation of <em>Norovirus </em>gastrointestinal illness through multiple nursing homes following a pilgrimage (Publications)
Reported here is an outbreak of gastroenteritis due to Norovirus infection that affected at least 450 persons from nursing homes and similar institutions in Switzerland during and after an organised p
Alkyl and dialkylaminoethyl derivatives of 5-amino-2-azabicyclo[3.2.2]nonanes and their antiplasmodial and antitrypanosomal activities (Publications)
N-Alkyl and N-(2-dialkylaminoethyl) derivatives of 5-amino-2-azabicyclo-nonanes were prepared and tested in vitro for their activities against the multidrug-resistant K1 strain of Plasmodium falciparu