Lipidomics and genomics of <em>Mycobacterium tuberculosis</em> reveal lineage-specific trends in mycolic acid biosynthesis (Publications)
Mycolic acids (MAs) are alpha-alkyl, beta-hydroxy long-chain fatty acids found in abundance in the cell envelope of the Mycobacterium tuberculosis complex (MTBC). MAs form an efficient permeability ba
Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds (Publications)
3-Hydroxy-N'-arylidenepropanehydrazonamides represent a new class of antiplasmodial compounds. The two most active phenanthrene-based derivatives showed potent in vitro antiplasmodial activity against
Clinical and socio-demographic predictors for virologic failure in rural Southern Africa: preliminary findings from CART-1 (Publications)
INTRODUCTION: In 2013, the World Health Organization (WHO) recommended scaling up of routine viral load (VL) monitoring for patients on antiretroviral therapy (ART) in resource-limited settings [1]. D
SOS2 and ACP1 loci identified through large-scale exome chip analysis regulate kidney development and function (Publications)
Genome-wide association studies have identified > 50 common variants associated with kidney function, but these variants do not fully explain the variation in eGFR. We performed a two-stage meta-analy
Improvements in PM10 exposure and reduced rates of respiratory symptoms in a cohort of Swiss adults (SAPALDIA) (Publications)
RATIONALE: Reductions in mortality following improvements in air quality were documented by several studies, and our group found, in an earlier analysis, that decreasing particulate levels attenuate l
Is age at menopause increasing across Europe? Results on age at menopause and determinants from two population-based studies (Publications)
OBJECTIVE: To investigate the variability and determinants of menopause age in two European cohort studies, the European Respiratory Health Survey and the Swiss Air Pollution and Lung Disease in Adult