The fight against lymphatic filariasis: perceptions of community drug distributors during mass drug administration in coastal Kenya (Publications)
BACKGROUND: Lymphatic filariasis (LF), a neglected tropical disease (NTD) and leading cause of global disability, is endemic in 32 countries in Africa with almost 350 million people requiring regular
Discovery of 4-((1-(1<em>H</em>-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of <em>Trypanosoma cruzi </em>growth inhibitors (Publications)
The identification of a new series of growth inhibitors of Trypanosoma cruzi, the causative agent of Chagas' disease, is described. In vitro screening of a subset of compounds from our in-house compou
Dual plasmepsin-targeting antimalarial agents disrupt multiple stages of the malaria parasite life cycle (Publications)
Artemisin combination therapy (ACT) is the main treatment option for malaria, which is caused by the intracellular parasite Plasmodium. However, increased resistance to ACT highlights the importance o
The immunology of other mycobacteria:<em> M. ulcerans, M. leprae</em> (Publications)
Mycobacterial pathogens can be categorized into three broad groups: Mycobacterium tuberculosis complex causing tuberculosis, M. leprae and M. lepromatosis causing leprosy, and atypical mycobacteria, o
Where there is no hospital: improving the notification of community deaths (Publications)
BACKGROUND: Globally, an estimated two-thirds of all deaths occur in the community, the majority of which are not attended by a physician and remain unregistered. Identifying and registering these dea
Better data for better outcomes: the importance of process mapping and management in CRVS systems (Publications)
BACKGROUND: Despite attempts to apply standard methods proven to work in high-income nations, nearly all civil registration and vital statistics (CRVS) systems in low- and middle-income countries are