Collaboration on Malaria drug discovery (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/collaboration-on-malaria-drug-discovery
The goal of this collaborative project with Actelion Pharmaceuticals is the discovery of new antimalarial molecules with unknown mechanism(s) of action. Cell-based antimalarial screens were performed
Antimalarial Drug Screening (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/antimalarial-drug-screening
Our mandate with Medicines for Malaria Venture in Geneva comprises exploratory work on novel compounds from various sources. The goal is to identify novel chemical entities showing antimalarial activi
Drug discovery for malaria based on novel drug targets in the NGBS Consortium (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/drug-discovery-for-malaria-based-on-novel-drug-targets-in-the-ngbs-consortium
The NGBS programme in malaria drug discovery is a collaboration between the Novartis Institute for Tropical Diseases (NITD), the Genomics Institute of the Novartis Research Foundation (GNF), the Biome
Women and Gynecology in Evaluation (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/women-and-gynecology-in-evaluation
Background The conceptual framework of Women's Health Centres (WHCs), created in the late nineteen seventies, has recently been reconsidered, firstly from the perspective of gender research and second
Phase 1 study in Tanzania to evaluate the safety and immunogenicity of BSPZV1 - a vaccine against Plasmodium falciparum sporozoite (PfSPZ) (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/phase-1-study-in-tanzania-to-evaluate-the-safety-and-immunogenicity-of-bspzv1-a-vaccine-against-plasmodium-falciparum-sporozoite-pfspz
Phase 1, dose escalation, randomized controlled trial to evaluate the safety, immunogenicity and efficacy of intravenously administered attenuated Plasmodium falciparum sporozoite vaccine (PfSPZ Vacci
MALARIA VACCINE - Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A With Alhydrogel (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/malaria-vaccine-safety-and-immunogenicity-of-novel-candidate-blood-stage-malaria-vaccine-p27a-with-alhydrogel
Further research and optimisation of new malaria vaccines and technologies is ongoing at Swiss TPH. This includes testing of new candidates in Africa such as P27a that was brought in one go from a Pha
Assessment of Current Intestinal Helminth-Related Data and Control Capacity in Moldova, Romania and Georgia (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/assessment-of-current-intestinal-helminth-related-data-and-control-capacity-in-moldova-romania-and-georgia
Objectives: To assess the level of awareness of intestinal helminth endemicity and the linkage between WASH and STH as well as planned actions of the health sector or other actors for STH survey, cont