Nonregistration, discontinuation, and nonpublication of randomized trials: a repeated metaresearch analysis (Publications)
BACKGROUND: We previously found that 25% of 1,017 randomized clinical trials (RCTs) approved between 2000 and 2003 were discontinued prematurely, and 44% remained unpublished at a median of 12 years f
Mental distress and health-related quality of life in <em>gambiense </em>human African trypanosomiasis: a case-control study in the Democratic... (Publications)
BACKGROUND: The extent to which neuropsychiatric sequelae affects the mental health status and quality of life of former gambiense human African trypanosomiasis (gHAT) patients is not known. METHODS:
Competent and deficient provision of childbirth services: a descriptive observational study assessing the quality of intrapartum care in two provinces... (Publications)
BACKGROUND: A majority of women in the Democratic Republic of the Congo (DRC) give birth in a health facility, but maternal and newborn mortality remains high. In rural areas, the quality of facility-
Genetically modified malaria parasites as vaccine candidates (Publications)
Induction of sterile immunity against sporozoite and liver stages of malaria is a long-standing aim in vaccine development. Genetically engineered, attenuated sporozoites were systematically evaluated
A comparison of statistical and machine-learning approaches for spatiotemporal modeling of nitrogen dioxide across Switzerland (Publications)
Land use regression modeling has commonly been used to model ambient air pollutant concentrations in environmental epidemiological studies. Recently, other statistical and machine-learning methods hav
Stigma-directed services (Stig2Health) to improve 'linkage to care' for people living with HIV in rural Tanzania: study protocol for a nested pre-post... (Publications)
Background: HIV-related stigma is a major barrier to the timely linkage and retention of patients in HIV care in sub-Saharan Africa, where most people living with HIV/AIDS reside. In this implementati
Perceived water-related risk factors of Buruli ulcer in two villages of south-central Côte d’Ivoire (Publications)
Background Buruli ulcer, caused by Mycobacterium ulcerans, is a neglected tropical skin disease that is primarily endemic in West and Central Africa, including Côte d’Ivoire. Studies indicate that M.
Long-term exposure to traffic-related air pollution and stroke: a systematic review and meta-analysis (Publications)
Background Stroke remains the second cause of death worldwide. The mechanisms underlying the adverse association of exposure to traffic-related air pollution (TRAP) with overall cardiovascular disease
Care cascades for hypertension and diabetes: cross-sectional evaluation of rural districts in Tanzania (Publications)
BACKGROUND: Noncommunicable diseases (NCDs), especially hypertension and diabetes, are rapidly rising in sub-Saharan Africa, necessitating health systems transformations. In Tanzania, current policies
Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased... (Publications)
BACKGROUND: While prior research has shown differences in the risk of malaria infection and sickness between males and females, little is known about sex differences in vaccine-induced immunity to mal