<em>Plasmodium falciparum</em> resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular... (Publications)
BACKGROUND: Molecular monitoring of parasite resistance has become an important complementary tool in establishing rational anti-malarial drug policies. Community surveys provide a representative samp
Genome-wide identification of molecular mimicry candidates in parasites (Publications)
Among the many strategies employed by parasites for immune evasion and host manipulation, one of the most fascinating is molecular mimicry. With genome sequences available for host and parasite, mimic
Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage rhodesiense sleeping sickness (Publications)
OBJECTIVE: Assessment of the safety and efficacy of a 10-day melarsoprol schedule in second stage T.b. rhodesiense patients and the effect of suramin-pretreatment on the incidence of encephalopathic s
Influence of <em>M. tuberculosis</em> lineage variability within a clinical trial for pulmonary tuberculosis (Publications)
Recent studies suggest that M. tuberculosis lineage and host genetics interact to impact how active tuberculosis presents clinically. We determined the phylogenetic lineages of M. tuberculosis isolate
Comparative genomics of metabolic networks of free-living and parasitic eukaryotes (Publications)
BACKGROUND: Obligate endoparasites often lack particular metabolic pathways as compared to free-living organisms. This phenomenon comprises anabolic as well as catabolic reactions. Presumably, the cor
Delivering at home or in a health facility? Health-seeking behaviour of women and the role of traditional birth attendants in Tanzania (Publications)
BACKGROUND: Traditional birth attendants retain an important role in reproductive and maternal health in Tanzania. The Tanzanian Government promotes TBAs in order to provide maternal and neonatal heal