Carotid intima-media thickness in the Spanish population: reference ranges and association with cardiovascular risk factors (Publications)
INTRODUCTION AND OBJECTIVES: Carotid intima-media thickness as measured with ultrasonography is an inexpensive and noninvasive predictor of cardiovascular events. The objectives of this study were to
The genome of the heartworm, <em>Dirofilaria immitis</em>, reveals drug and vaccine targets (Publications)
The heartworm Dirofilaria immitis is an important parasite of dogs. Transmitted by mosquitoes in warmer climatic zones, it is spreading across southern Europe and the Americas at an alarming pace. The
New N-methylpiperazinyl derivatives of bicyclic antiprotozoal compounds (Publications)
The 4-methylpiperazinyl group was inserted as substituent at the bridgehead of bicyclic compounds or as terminal group of their aminoacyl and aminoalkyl side chains. The new compounds were tested in v
Dialkylaminoalkyl derivatives of bicyclic compounds with antiplasmodial activity (Publications)
Dialkylaminoalkyl derivatives of 2-azabicyclo[3.2.2]nonanes and of bicyclo[2.2.2]octanes were prepared and their activities determined in vitro against the multiresistant K(1) strain of Plasmodium fal
Antiplasmodial and antitrypanosomal activity of bicyclic amides and esters of dialkylamino acids (Publications)
Several bicyclic amides and esters of dialkylamino acids were prepared. Their activities against a multiresistant strain of Plasmodium falciparum and against Trypanosoma brucei rhodesiense (STIB 900)