Thermotherapy of Buruli Ulcer at Community Level, Cameroon (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/thermotherapy-of-buruli-ulcer-at-community-level-cameroon
Treatment of the neglected tropical skin disease Buruli Ulcer (BU) relies currently on a single drug, rifampicin, which is given in combination with streptomycin. Development of an alternative treatme
Lufthygienische Dokumentationsstelle 2018-2021 (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/lufthygienische-dokumentationsstelle-2018-2021
Die vom Bundesamt für Umwelt (BAFU) finanzierte Dokumentationsstelle LUDOK am Schweizerischen Tropen und Public Health Institut (Swiss TPH) liefert seit 30 Jahren evidenzbasierte Informationen zu den
Efficacy and safety of fexinidazole in patients with Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense: a multicentre,... (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/efficacy-and-safety-of-fexinidazole-in-patients-with-human-african-trypanosomiasis-hat-due-to-trypanosoma-brucei-rhodesiense-a-multicentre-open-label-clinical-trial
A vector-borne parasitic illness, human African trypanosomiasis (HAT), also known as sleeping sickness, is usually fatal without treatment. The less prevalent form, T.b. rhodesiense (r-HAT), is concen
Evolution and Epidemiology of Rifampicin-Resistant Tuberculosis in Khayelitsha, Cape Town: Implications for Biology and Disease Control (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/evolution-and-epidemiology-of-rifampicin-resistant-tuberculosis-in-khayelitsha-cape-town-implications-for-biology-and-disease-control
Background Bacteria resistant to multiple antibiotics are a growing threat for global public health and the economy. Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant TB (XDR-TB
Drug discovery and development for schistosomiasis: From repositioning of antimalarial drug leads and clinical advanced drug candidates to the... (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/drug-discovery-and-development-for-schistosomiasis-from-repositioning-of-antimalarial-drug-leads-and-clinical-advanced-drug-candidates-to-the-development-of-a-new-paediatric-formulation-of-praziquantel
The aim of my 4-year research project is to identify one or several antischistosomal drug development candidates targeting the haemoglobin degradation pathway and/or other mechanisms with favourable p
Analysing in-hospital mortality and morbidity in Côte d’Ivoire: implications for HIV/Aids, Malaria and TB (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/analysing-in-hospital-mortality-and-morbidity-in-cote-divoire-implications-for-hiv/aids-malaria-and-tb
sAnalysing routine data from health facilities across the country, the study intends to analyse trends in mortality and morbidity for HIV/Aids, Malaria and TB between 2010-2015. The Swiss TPH provides
Efficacy and safety of moxidectin plus albendazole, moxidectin plus tribendimidine, albendazole plus oxantel pamoate and moxidectin alone against... (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/efficacy-and-safety-of-moxidectin-plus-albendazole-moxidectin-plus-tribendimidine-albendazole-plus-oxantel-pamoate-and-moxidectin-alone-against-trichuris-trichiura-and-concomitant-soil-transmitted-helminth-infections-a-randomized-controlled-trial
The recommended anthelmintics show low efficacy in a single-dose regimen against Trichuris trichiura. Moxidectin, a new treatment for river blindness, might complement the drug armamentarium for the t
Infected body on a chip”: Microfluidic impedance platform for antischistosomal drug discovery (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/infected-body-on-a-chip-microfluidic-impedance-platform-for-antischistosomal-drug-discovery
Many new methods in drug discovery originate from the field of microfluidics, which also include innovative methods to monitor the status of cells or tissues by means of electric impedance spectroscop
Ensuring the Efficacy of Mass Drug Administration Drugs for Soil-Transmitted Helminths (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/ensuring-the-efficacy-of-mass-drug-administration-drugs-for-soil-transmitted-helminths
The overall objective of the investment is to establish a surveillance system that globally monitors the eficacy of drugs and spread of AR in STH programs, and hence prevailing the success of MDA prog