Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin (Publications)
Chemical investigation of the marine sponge Plakortis cfr. lita afforded a library of endoperoxyketal polyketides, manadoperoxides B-K (3-5 and 7-13) and peroxyplakoric esters B(3) (6) and C (14). Eig
Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents (Publications)
We report herein the synthesis and trypanocidal profile of new (E)-cinnamic N-acylhydrazones (NAHs) designed by exploiting molecular hybridization between the potent cruzain inhibitors (E)-1-(benzo[d]
Pharmacotherapy, vaccines and malaria advice for HIV-infected travellers (Publications)
Since the introduction of effective antiretroviral therapy (ART), HIV-infected individuals are travelling more frequently and international travel has become much safer. Specific concerns include the
The influence of sensitisation to pollens and moulds on seasonal variations in asthma attacks (Publications)
No large study has described seasonal variation in asthma attacks in population based asthmatics in whom sensitisation to allergen has been measured.2,637 young adults with asthma living in 15 countri