The structure-activity relationship of the antimalarial ozonide arterolane (OZ277) (Publications)
The structure and stereochemistry of the cyclohexane substituents of analogues of arterolane (OZ277) had little effect on potency against Plasmodium falciparum in vitro. Weak base functional groups we
Participatory mapping of target areas to enable operational larval source management to suppress malaria vector mosquitoes in Dar es Salaam, Tanzania (Publications)
ABSTRACT: BACKGROUND: Half of the population of Africa will soon live in towns and cities where it can be protected from malaria by controlling aquatic stages of mosquitoes. Rigorous but affordable an
Not all farming environments protect against the development of asthma and wheeze in children (Publications)
BACKGROUND: In recent years, studies have shown a protective effect of being raised in a farm environment on the development of hay fever and atopic sensitization. Inconsistent data on the relation of
Differences in aerobic fitness and lifestyle characteristics in preschoolers according to their weight status and sports club participation (Publications)
Objective: This study assesses differences in adiposity, aerobic fitness, and lifestyle characteristics in preschoolers according to their weight status and sports club (SC) participation. Method: As
Ernährungserziehung im Kindergarten: Resultate einer Interventionsstudie (Publications)
The nutrition intervention in the case of the 3 target groups (children, kindergarten teachers and parents) with regard to knowledge, awareness of nutrition problems, efforts to make changes and the a
Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes (Publications)
This paper describes the discovery of synthetic 1,2,4-trioxolane antimalarials and how we established a workable structure-activity relationship in the context of physicochemical, biopharmaceutical, a