Kinetic characterization of squalene synthase from<em> Trypanosoma cruzi:</em> selective inhibition by quinuclidine derivatives (Publications)
The biosynthesis of sterols is a major route for the development of antitrypanosomals. Squalene synthase (SQS) catalyzes the first step committed to the biosynthesis of sterols within the isoprenoid p
The current status of opisthorchiasis and clonorchiasis in the Mekong Basin (Publications)
This review highlights the current status and control of liver fluke infections in the Mekong Basin countries where Opisthorchis and Clonorchis are highly endemic. Updated data on prevalence and distr
Helminth infections and risk factor analysis among residents in Eryuan county, Yunnan province, China (Publications)
Whilst infections with soil-transmitted helminths are common across China, the public-health significance of Schistosoma japonicum and food-borne helminths is more focalized. Only few studies have inv
Large-scale determinants of intestinal schistosomiasis and intermediate host snail distribution across Africa: does climate matter? (Publications)
The geographical ranges of most species, including many infectious disease agents and their vectors and intermediate hosts, are assumed to be constrained by climatic tolerances, mainly temperature. It
The distribution of <em>Biomphalaria</em> (Gastropoda: Planorbidae) in Lake Victoria with ecological and spatial predictions using Bayesian modelling (Publications)
Intestinal schistosomiasis is a global disease of enormous public health importance. Assessing the local risk of transmission of the parasite causing the disease requires an appraisal of the distribut
Lung function decline, chronic bronchitis, and occupational exposures in young adults (Publications)
RATIONALE: Occupational exposures to vapors, gas, dust, or fumes have been shown to be a risk factor of airway obstruction in cross-sectional studies in the general population. OBJECTIVES: Our aim was