Integrative pathway genomics of lung function and airflow obstruction (Publications)
Chronic respiratory disorders are important contributors to the global burden of disease. Genome-wide association studies (GWASs) of lung function measures have identified several trait-associated loc
Santé sexuelle: variabilités en Suisse et en Europe (Publications)
Sexual Health is interrelated with both, sex and gender, through its biological dimension, its connection with cultural conventions, and its impact on women's health. Reproductive factors are presente
Serum bilirubin is associated with lung function in a Swiss general population sample (Publications)
Bilirubin is a strong antioxidant. Increased serum levels were associated with respiratory disease and mortality risk. We studied the association of bilirubin with lung function in the SAPALDIA cohort
Spatial variation of PM elemental compositon between and within 20 European study areas - results of the ESCAPE project (Publications)
An increasing number of epidemiological studies suggest that adverse health effects of air pollution may be related to particulate matter (PM) composition, particularly trace metals. However, we lack
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets (Publications)
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function and is the third leading cause of death globally. Through genome-wide association discovery in 48,943 individuals
Land use regression models for ultrafine particles in six European areas (Publications)
Long-term ultrafine particle (UFP) exposure estimates at a fine spatial scale are needed for epidemiological studies. Land use regression (LUR) models were developed and evaluated for six European are
Ambient air pollution and adult asthma incidence in six European cohorts (ESCAPE) (Publications)
BACKGROUND: Short-term exposure to air pollution has adverse effects among patients with asthma, but whether long-term exposure to air pollution is a cause of adult-onset asthma is unclear. OBJECTIVE:
Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland (Publications)
Most studies published to date consider single noise sources and the reported noise metrics are not informative about the peaking characteristics of the source under investigation. Our study focuses o