Old and new selective pressures on <em>Mycobacterium tuberculosis</em> (Publications)
Tuberculosis (TB) has been affecting humans for millennia. There is increasing indication that human-adapted Mycobacterium tuberculosis complex (MTBC) has been co-evolving with different human populat
Respiratory health and long-term exposure to air pollutants in Swiss schoolchildren (Publications)
The impact of long-term exposure to air pollution on respiratory and allergic symptoms and illnesses was assessed in a cross-sectional study of schoolchildren (ages 6 to 15 yr, n = 4,470) living in 10
Bronchial hyperresponsiveness and the development of asthma and COPD in asysmptomatic individuals - SAPALDIA cohort study (Publications)
Background: Bronchial hyperresponsiveness (BHR) is a common feature of asthma. However, BHR is also present in asymptomatic individuals and its clinical and prognostic significance is unclear. We hypo
The phenomenon of treatment failures in human African trypanosomiasis (Publications)
Treatment of Human African Trypanosomiasis (HAT or sleeping sickness) relies on a few drugs which are old, toxic and expensive. The most important drug for the treatment of second stage infection is m
Lung function in healthy never smoking adults: reference values and lower limits of normal of a Swiss population (Publications)
BACKGROUND: Reference values and definitions of "normal" are prerequisites for population screening and classification of lung diseases. The aim of this study was to calculate reference values for nev
Medical and economic long-term effects of B-type natriuretic peptide testing in patients with acute dyspnea (Publications)
BACKGROUND: The objective of this prospective study was to assess the medical and economic long-term effects of using B-type natriuretic peptide (BNP) concentrations in the management of patients with