Antitrypanosomal and antiplasmodial activity of medicinal plants from Côte d' Ivoire (Publications)
The antitrypanosomal activity of 101 crude ethanol extracts derived from 88 medicinal plants from Côte d'Ivoire was determined in vitro using Trypanosoma brucei rhodesiense. Of those extracts 8 showed
Methotrexate and aminopterin lack in vivo antimalarial activity against murine malaria species (Publications)
The antifolate anticancer drug methotrexate (MTX) has potent activity against Plasmodium falciparum in vitro. Experience of its use in the treatment of rheumatoid arthritis indicates that it could be
Exploring prospects of novel drugs for tuberculosis (Publications)
Tuberculosis remains a disease with an enormous impact on public health worldwide. With the continuously increasing epidemic of drug-resistant tuberculosis, new drugs are desperately needed. However,
Antitrypanosomal sesquiterpene lactones from <em>Saussurea costus</em> (Publications)
In the course of a larger screen of 1800 plant and fungal extracts, the ethyl acetate extract of Saussurea costus roots potently inhibited the growth of Trypanosoma brucei rhodesiense. Subsequent HPLC