Presence of nonhemolytic pneumolysin in serotypes of <em>Streptococcus pneumoniae</em> associated with disease outbreaks (Publications)
Pneumolysin is an important virulence factor of the human pathogen Streptococcus pneumoniae. Sequence analysis of the ply gene from 121 clinical isolates of S. pneumoniae uncovered a number of alleles
Spousal violence in Bangladesh: a call for a public-health response (Publications)
Spousal violence against women is a serious public-health issue. Although there is a growing body of literature on this subject, there are still many unanswered questions regarding the prevalence of t
Longitudinal assessment of <em>Plasmodium falciparum v</em>ar gene transcription in naturally infected asymptomatic children in Papua New Guinea (Publications)
Sequestration and antigenic variation are essential for Plasmodium falciparum survival in vivo contributing to severe pathologic findings and, also, chronic infection. Both are conferred by P. falcipa
Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents (Publications)
A series of near-linear biphenyl benzimidazole diamidines 5a-h were synthesized from their respective diamidoximes (4a-h), through the bis-O-acetoxyamidoxime, followed by hydrogenation in glacial acet
Association of daily physical activity volume and intensity with COPD severity (Publications)
PURPOSE: The purpose of this study was to assess whether daily walking activity is indicative of disease severity in patients with COPD. METHODS: Daily activity was measured by accelerometry in 107 CO
Air pollution attributable postneonatal infant mortality in U.S. metropolitan areas: a risk assessment study (Publications)
BACKGROUND: The impact of outdoor air pollution on infant mortality has not been quantified. METHODS: Based on exposure-response functions from a U.S. cohort study, we assessed the attributable risk o
Environmental health indicators in policy evaluation (Publications)
In carrying out two projects involving environmental health indicators--a national environmental health programme evaluation and an international environmental health indicator system--in parallel, it
Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents (Publications)
A series of analogues of the naturally occurring antibiotic thiolactomycin (TLM) have been synthesised and evaluated for their ability to inhibit the growth of the malaria parasite, Plasmodium falcipa