TbIRK is a signature sequence free potassium channel from <em>Trypanosoma brucei</em> locating to acidocalcisomes (Publications)
Potassium channels from prokaryotes and eukaryotes are usually recognized by a typical amino acid sequence TXTGY(F)G representing the ionic selectivity filter. Using a screening approach with ion chan
European Community Respiratory Health Survey II : final report of work package 6 : PM2.5 assessment in 21 European cities of ECRHS II (Publications)
The follow-up of a cohort of adults from 29 European centres of the former ECRHS I (1989-1992) will examine the long-term effects of exposure to ambient air pollution on the incidence, course, and pro
Cost description and comparative cost efficiency of post-exposure prophylaxis and canine mass vaccination against rabies in N'Djamena, Chad (Publications)
Rabies claims approximately 59,000 human lives annually and is a potential risk to 3.3 billion people in over 100 countries worldwide. Despite being fatal in almost 100% of cases, human rabies can be
Improving household air, drinking water and hygiene in rural Peru: a community-randomized-controlled trial of an integrated environmental home-based... (Publications)
BACKGROUND: Diarrhoea and acute lower respiratory infections are leading causes of childhood morbidity and mortality, which can be prevented by simple low-cost interventions. Integrated strategies can
Childhood vaccination communication outcomes unpacked and organised in a taxonomy to facilitate core outcome establishment (Publications)
OBJECTIVE: We present a comprehensive taxonomy of outcomes for childhood vaccination communication interventions. Adding to our earlier map of trial outcomes, we aimed to: 1) identify relevant outcome
Antimicrobial resistance in <em>Mycobacterium tuberculosis</em>: mechanistic and evolutionary perspectives (Publications)
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically resistant to many antibioti
Metabolic syndrome in patients on first-line antiretroviral therapy containing zidovudine or tenofovir in rural Lesotho, Southern Africa (Publications)
OBJECTIVE: To assess the prevalence of metabolic syndrome (MetS) among patients in rural Lesotho who are taking first-line anti-retroviral therapy (ART) containing either zidovudine or tenofovir disop
Transient hyperglycemia in patients with tuberculosis in Tanzania: implications for diabetes screening algorithms (Publications)
BACKGROUND: Diabetes mellitus (DM) increases tuberculosis (TB) risk while TB, as an infectious disease, leads to hyperglycemia. We compared hyperglycemia screening strategies in controls and TB patien