Discovery of antischistosomal drug leads based on tetraazamacrocyclic derivatives and their metal complexes (Publications)
Praziquantel (PZQ) is the only available drug to treat schistosomiasis, and since its large scale use might be associated with the onset of resistance, new antischistosomal drugs should be developed.
School distribution as keep-up strategy to maintain universal coverage of long-lasting insecticidal nets: implementation and results of a program in... (Publications)
Tanzania successfully scaled up coverage of long-lasting insecticidal nets (LLINs) through mass campaigns. To sustain these gains, a school-based approach was piloted in the country's Southern Zone st
Successful comeback of the single-dose live oral cholera vaccine CVD 103-HgR (Publications)
Effective and easy to administer cholera vaccines are in need more than ever, for at risk populations and travellers alike. In many parts of the world cholera is still endemic, causing outbreaks and c
Evaluation of the in vivo activity of tribendimidine against <em>Schistosoma mansoni, Fasciola hepatica, Clonorchis sinensis,</em> and... (Publications)
We examined the in vivo activity of tribendimidine against selected trematodes. A single 150-mg/kg dose of tribendimidine achieved a 99.1% reduction of Clonorchis sinensis in rats. A 400-mg/kg dose of
The effect of zinc supplementation on body composition and hormone levels related to adiposity among children: a systematic review (Publications)
OBJECTIVE: To provide a comprehensive synthesis of the effects of Zn supplementation on childhood body composition and adiposity-related hormone levels. DESIGN: Five electronic databases were searched
Local and foreign authorship of maternal health interventional research in low- and middle-income countries: systematic mapping of publications... (Publications)
BACKGROUND: Researchers in low- and middle-income countries (LMICs) are under-represented in scientific literature. Mapping of authorship of articles can provide an assessment of data ownership and re
Dose-response relationships and tegumental surface alterations in <em>Opisthorchis viverrini</em> following treatment with mefloquine in vivo and in... (Publications)
The treatment and control of opisthorchiasis relies on a single drug, praziquantel; hence, there is a need to develop novel opisthorchicidal drugs. We investigated the in vitro and in vivo activity of