High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds (Publications)
Rapidly spreading antibiotic resistance and the low discovery rate of new antimicrobial compounds demand more effective strategies for early drug discovery. One bottleneck in the drug discovery pipeli
Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic... (Publications)
African trypanosomiasis is a neglected parasitic disease that is still of great public health relevance, and a severe impediment to agriculture in endemic areas. The pathogens possess certain unique m
Impact of diagnostic test Xpert MTB/RIF® on health outcomes for tuberculosis (Publications)
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: to assess the impact of Xpert MTB/RIF on important patient outcomes for people with tuberculosis.
On a mission to block transmission (Publications)
The controlled infection of volunteers with Plasmodium falciparum parasites could provide a platform to evaluate new drugs and vaccines aimed at blocking malaria transmission.
WHO environmental noise guidelines for the European region: a systematic review on environmental noise and cardiovascular and metabolic effects: a... (Publications)
To update the current state of evidence and assess its quality, we conducted a systematic review on the effects of environmental noise exposure on the cardio-metabolic systems as input for the new WHO
Comparison of antigen and antibody responses in repeat lymphatic filariasis transmission assessment surveys in American Samoa (Publications)
BACKGROUND: Current WHO recommendations for lymphatic filariasis (LF) surveillance advise programs to implement activities to monitor for new foci of transmission after stopping mass drug administrati