Ealamines A-H, a series of naphthylisoquinolines with the rare 7,8'-coupling site, from the Congolese liana <em>Ancistrocladus ealaensis</em>,... (Publications)
From the twigs and leaves of the Central African liana Ancistrocladus ealaensis (Ancistrocladaceae), a series of ten 7,8'-coupled naphthylisoquinoline alkaloids were isolated, comprising eight new com
Exploring mechanochemical parameters using a DoE approach: crystal structure solution from Synchrotron XRPD and characterization of a new praziquantel... (Publications)
A rotated Doehlert matrix was utilized to explore the experimental design space around the milling parameters of Praziquantel (PZQ) polymorph B formation in terms of frequency and milling time. Three
Classifying recurrent <em>Mycobacterium tuberculosis </em>cases in Georgia using MIRU-VNTR typing (Publications)
INTRODUCTION: Recurrent tuberculosis (TB) is one of the main challenges in TB control. Genotyping based on Mycobacterial Interspersed Repetitive Units-Variable Tandem Repeats (MIRU-VNTR) has been wide
Flexible 3D cell-based platforms for the discovery and profiling of novel drugs targeting <em>Plasmodium</em> hepatic infection (Publications)
The restricted pipeline of drugs targeting the liver stage of Plasmodium infection reflects the scarcity of cell models that mimic the human hepatic phenotype and drug metabolism, as well as Plasmodiu
Methods and data needs to assess health impacts of chemicals in industrial contaminated sites (Publications)
BACKGROUND: human exposure to mixtures of chemicals of toxicological interest, typically found in industrial contaminated sites (ICSs), has been associated with a broad range of different health outco
The PHIST protein GEXP02 targets the host cytoskeleton during sexual development of <em>Plasmodium falciparum</em> (Publications)
A hallmark of the biology of Plasmodium falciparum blood stage parasites is their extensive host cell remodeling, facilitated by parasite proteins that are exported into the erythrocyte. Although this
Human biomonitoring as a tool for exposure assessment in industrially contaminated sites (ICSs). Lessons learned within the ICS and Health European... (Publications)
BACKGROUND: the mixed and complex nature of industrially contaminated sites (ICSs) leads to heterogeneity in exposure and health risk of residents living nearby. Health, environment, and social aspect