<em>Plasmodium falciparum</em> heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors (Publications)
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded
Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and <em>Taenia </em>spp<em>.</em>: a randomized... (Publications)
BACKGROUND: The control of soil-transmitted helminth (STH) infections currently relies on the large-scale administration of single-dose oral albendazole or mebendazole. However, these treatment regime
In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for <em>T.b. gambiense</em> sleeping sickness (Publications)
BACKGROUND: Trypanosoma brucei (T.b.) gambiense Human African trypanosomiasis (HAT; sleeping sickness) is a fatal disease. Until 2009, available treatments for 2(nd) stage HAT were complicated to use,
Phylogenomics of ligand-gated ion channels predicts monepantel effect (Publications)
The recently launched veterinary anthelmintic drench for sheep (Novartis Animal Health Inc., Switzerland) containing the nematocide monepantel represents a new class of anthelmintics: the amino-aceton