Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of <em>Plasmodium falciparum</em> enoyl-ACP-reductase... (Publications)
Malaria, a disease of worldwide significance, is responsible for over one million deaths annually. The liver-stage of Plasmodium's life cycle is the first, obligatory, but clinically silent step in ma
Substituted 2-phenyl-imidazopyridines: a new class of drug leads for human African trypanosomiasis (Publications)
A phenotypic screen of a compound library for antiparasitic activity on Trypanosoma brucei, the causative agent of human African trypanosomiasis, led to the identification of substituted 2-(3-aminophe
The prevalence and distribution of food sensitization in european adults (Publications)
BACKGROUND: Complaints of 'food allergy' are increasing. Standardized surveys of IgE sensitization to foods are still uncommon and multicountry surveys are rare. We have assessed IgE sensitization to
Acute-phase proteins and mortality in status epilepticus: a 5-year observational cohort study (Publications)
OBJECTIVE: Acute-phase proteins, such as C-reactive protein and albumin, may be related with course and outcome in status epilepticus, as changes of cytokine levels and blood-brain barrier breakdown d
Antitrypanosomal isothiocyanate and thiocarbamate glycosides from <em>Moringa peregrina </em>[Letter] (Publications)
O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(alpha-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(alpha-L-rhamnosyloxy) benzyl isothiocyanate (4) have been isolated from the aerial parts o
Evaluation of four single-locus markers for <em>Leishmania</em> species discrimination by sequencing (Publications)
Several genetic markers have been described for discriminating Leishmania species. In most reported cases, one or a few polymorphisms are the basis of species identification, and the methods were vali