Ambient ultrafine particle levels at residential and reference sites in urban and rural Switzerland (Publications)
Although there is evidence that ultrafine particles (UFP) do affect human health there are currently no legal ambient standards. The main reasons are the absence of spatially resolved exposure data to
Carotid stiffness and physical activity in elderly: a short report of the SAPALDIA 3 cohort study (Publications)
INTRODUCTION: Regular physical activity has been shown to reduce cardiovascular disease risk in the general population. While smaller studies in specified groups (highly trained versus untrained indiv
Comparing land use regression and dispersion modelling to assess residential exposure to ambient air pollution for epidemiological studies (Publications)
BACKGROUND: Land-use regression (LUR) and dispersion models (DM) are commonly used for estimating individual air pollution exposure in population studies. Few comparisons have however been made of the
Long-term effects of elemental composition of particulate matter on inflammatory blood markers in European cohorts (Publications)
BACKGROUND: Epidemiological studies have associated long-term exposure to ambient particulate matter with increased mortality from cardiovascular and respiratory disorders. Systemic inflammation is a
The locus <em>C11orf30</em> increases susceptibility to poly-sensitization (Publications)
A number of genetic variants have been associated with allergic sensitization, but whether these are allergen specific or increase susceptibility to poly-sensitization is unknown. Using data from the
Follow-up on genome-wide main effects: do polymorphisms modify the air pollution effect on lung function decline in adults? (Publications)
Improved air quality has been found associated with attenuated age-related decline in lung function. But whether genetic polymorphisms strongly associated with lung function play a modifying role in t
Long-term physical activity is associated with reduced arterial stiffness in older adults: longitudinal results of the SAPALDIA cohort study (Publications)
BACKGROUND: longitudinal analyses of physical activity (PA) and arterial stiffness in populations of older adults are scarce. We examined associations between long-term change of PA and arterial stiff
Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis (Publications)
Asthma and chronic obstructive pulmonary disease (COPD) are thought to share a genetic background ("Dutch hypothesis"). We investigated whether asthma and COPD have common underlying genetic factors,