Clonorchicidal properties of the synthetic trioxolane OZ78 (Publications)
Because the synthetic trioxolane OZ78 is active against the liver fluke Fasciola hepatica, we were motivated to investigate the in vivo and in vitro activity against another liver fluke, namely Clonor
Confounding and effect modification in the short-term effects of ambient particles on total mortality: results from 29 European cities within the... (Publications)
We present the results of the Air Pollution and Health: A European Approach 2 (APHEA2) project on short-term effects of ambient particles on mortality with emphasis on effect modification. We used dai
Beijing sublineages of <em>Mycobacterium tuberculosis</em> differ in pathogenicity in the Guinea pig (Publications)
The Beijing family of Mycobacterium tuberculosis strains is part of lineage 2 (also known as the East Asian lineage). In clinical studies, we have observed that isolates from the sublineage RD207 of l
Artemisinins and synthetic trioxolanes in the treatment of helminth infections (Publications)
PURPOSE OF REVIEW: Helminthiases, including schistosomiasis and food-borne trematodiasis, affect millions of people. Just a few drugs are used for the treatment and control of these diseases. We revie
<em>Fasciola hepatica</em>: surface tegumental responses to in vitro and in vivo treatment with the experimental fasciolicide OZ78 (Publications)
The tegumental alterations in adult Fasciola hepatica induced by the experimental fasciolide OZ78 were investigated utilizing scanning electron microscopy (SEM). Twelve weeks post-infection with F. he
A single FLOTAC is more sensitive than triplicate Kato-Katz for the diagnosis of low-intensity soil-transmitted helminth infections (Publications)
Accurate diagnostic tools are pivotal for patient management and surveillance of helminth control programmes, particularly in the current era of preventive chemotherapy. Three consecutive stool sample
Weight-bearing bones are more sensitive to physical exercise in boys than in girls during pre- and early puberty: a cross-sectional study (Publications)
We carried out a cross-section study of the sex-specific relationship between bone mineral content and physical activity at sites with different loading in pre- and early pubertal girls and boys. Ther
Albendazole and mebendazole administered alone or in combination with Ivermectin against <em>Trichuris trichiura</em>: a randomized controlled trial (Publications)
Background. Single-dose albendazole and mebendazole show limited efficacy in the treatment of trichuriasis. The combination of albendazole with ivermectin improves efficacy, but a mebendazole-ivermect