Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections (Publications)
BACKGROUND: Amplicon deep sequencing permits sensitive detection of minority clones and improves discriminatory power for genotyping multi-clone Plasmodium falciparum infections. New amplicon sequenci
Population structure and virulence gene profiles of <em>Streptococcus agalactiae </em>collected from different hosts worldwide (Publications)
Streptococcus agalactiae is a leading cause of morbidity and mortality among neonates and causes severe infections in pregnant women and nonpregnant predisposed adults, in addition to various animal s
African animal trypanosomiasis as a constraint to livestock health and production in Karamoja region: a detailed qualitative and quantitative... (Publications)
BACKGROUND: Nagana (African Animal Trypanosomiasis-AAT) and tick-borne diseases (TBDs) constrain livestock production in most parts of sub-Saharan Africa. To this realisation, Uganda government set up
Do surveys with paper and electronic devices differ in quality and cost? Experience from the Rufiji Health and Demographic Surveillance System in... (Publications)
BACKGROUND: Data entry at the point of collection using mobile electronic devices may make data-handling processes more efficient and cost-effective, but there is little literature to document and qua
malERA: an updated research agenda for malaria elimination and eradication (Publications)
Achieving a malaria-free world presents exciting scientific challenges as well as overwhelming health, equity, and economic benefits. WHO and countries are setting ambitious goals for reducing the bur
Efficacy and safety of tribendimidine versus praziquantel against <em>Opisthorchis viverrini</em> in Laos: an open-label, randomised, non-inferiority,... (Publications)
BACKGROUND: Praziquantel is the only option for treatment of the liver fluke infection Opisthorchis viverrini. Tribendimidine could be an alternative drug. We aimed to assess the efficacy and safety o
The ethics of health care delivery in a pediatric malaria vaccine trial: the perspectives of stakeholders from Ghana and Tanzania (Publications)
This study explores ethical issues raised in providing medical care to participants and communities of low-resource settings involved in a Phase II/III pediatric malaria vaccine trial (PMVT). We condu
Antiprotozoal spirombandakamines A1 and A2, fused naphthylisoquinoline dimers from a Congolese <em>Ancistrocladus </em>plant (Publications)
From the leaves of a yet undescribed Congolese Ancistrocladus species, two novel naphthylisoquinoline dimers, spirombandakamines A1 (1) and A2 (2), were isolated, together with a new, but "classical"
Interventions to increase tuberculosis case detection at primary healthcare or community-level services (Publications)
BACKGROUND: Pulmonary tuberculosis is usually diagnosed when symptomatic individuals seek care at healthcare facilities, and healthcare workers have a minimal role in promoting the health-seeking beha