Misdiagnosis of leprosy in Brazil in the period 2003-2017: spatial pattern and associated factors (Publications)
BACKGROUND: Leprosy causes a range of symptoms, and most diagnoses are established based on the clinical picture. Therefore, false negative and positive diagnoses are relatively common. We analyzed th
Emergence of artemisinin-resistant <em>Plasmodium falciparum</em> with <em>kelch13 </em>C580Y mutations on the island of New Guinea (Publications)
The rapid and aggressive spread of artemisinin-resistant Plasmodium falciparum carrying the C580Y mutation in the kelch13 gene is a growing threat to malaria elimination in Southeast Asia, but there i
Accuracy of different diagnostic techniques for <em>Schistosoma haematobium</em> to estimate treatment needs in Zimbabwe: application of a... (Publications)
BACKGROUND: Treatment needs for Schistosoma haematobium are commonly evaluated using urine filtration with detection of parasite eggs under a microscope. A common symptom of S. haematobium is hematuri
Evaluation of seasonal malaria chemoprevention in two areas of intense seasonal malaria transmission: secondary analysis of a household-randomised,... (Publications)
BACKGROUND: Seasonal malaria chemoprevention (SMC) is now widely deployed in the Sahel, including several countries that are major contributors to the global burden of malaria. Consequently, it is imp
Medicinal chemistry optimization of a diaminopurine chemotype: toward a lead for <em>Trypanosoma brucei</em> inhibitors (Publications)
Human African trypanosomiasis (HAT), or sleeping sickness, is caused by the protozoan parasite Trypanosoma brucei and transmitted through the bite of infected tsetse flies. The disease is considered f
Registration and local production of essential medicines in Uganda (Publications)
Background: Universal access to high quality essential medicines is critical to sustainable development (SDG 3.8). However low- and middle-income countries struggle to ensure access to all medicines o
Cross-reaction of POC-CCA urine test for detection of <em>Schistosoma mekongi</em> in Lao PDR: a cross-sectional study (Publications)
BACKGROUND: The point-of-care circulating cathodic antigen (POC-CCA) test is increasingly used as a rapid diagnostic method for Schistosoma mansoni infection. The test has good sensitivity, although f