Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities (Publications)
Several of the enzymes related to the folate cycle are well-known for their role as clinically validated antimalarial targets. Nevertheless for serine hydroxymethyltransferase (SHMT), one of the key e
The WHO ultrasonography protocol for assessing morbidity due to <em>Schistosoma haematobium</em>: acceptance and evolution over 14 years: systematic... (Publications)
In 2000, the World Health Organization (WHO) published an ultrasound field protocol for assessing morbidity due to schistosomiasis. The present study aims to review the acceptance of the WHO protocol
Cost and sensitivity of on-farm versus slaughterhouse surveys for prevalence estimation and substantiating freedom from disease (Publications)
Within the framework of Swiss surveillance for epizootic diseases, dairy cattle are sampled using bulk tank milk while non-dairy cattle are sampled on the farm. The latter method is costly, time-deman
Skin and soft tissue infections in intercontinental travellers and the import of multi-resistant <em>Staphylococcus aureus</em> to Europe (Publications)
Staphylococcus aureus is emerging globally. Treatment of infections is complicated by increasing antibiotic resistance. We collected clinical data and swabs of returnees with skin and soft tissue infe
Health & demographic surveillance system profile: the Rufiji Health and Demographic Surveillance System (Rufiji HDSS) (Publications)
The Rufiji Health and Demographic Surveillance System (HDSS) was established in October 1998 to evaluate the impact on burden of disease of health system reforms based on locally generated data, prior
Molecular epidemiology suggests Venezuela as the origin of the dengue outbreak in Madeira, Portugal in 2012-2013 (Publications)
An explosive epidemic occurred in Madeira Island (Portugal) from October 2012 to February 2013. Published data showed that Dengue virus type 1 DENV-1) introduced from South America was the incriminate
Perspectives of family members participating in cultural assessment of psychiatric disorders: findings from the DSM-5 international field trial (Publications)
Abstract Despite the important roles families play in the lives of many individuals with mental illness across cultures, there is a dearth of data worldwide on how family members perceive the process
Co-evolution of <em>Mycobacterium tuberculosis</em> and <em>Homo sapiens</em> (Publications)
The causative agent of human tuberculosis (TB), Mycobacterium tuberculosis, is an obligate pathogen that evolved to exclusively persist in human populations. For M. tuberculosis to transmit from perso