Identification of compounds with anti-proliferative activity against <em>Trypanosoma brucei brucei</em> strain 427 by a whole cell viability based HTS... (Publications)
Human African Trypanosomiasis (HAT) is caused by two trypanosome sub-species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Drugs available for the treatment of HAT have significant
<em>Anopheles plumbeus</em> (Diptera: Culicidae) in Europe: a mere nuisance mosquito or potential malaria vector? (Publications)
ABSTRACT: BACKGROUND: Anopheles plumbeus has been recognized as a minor vector for human malaria in Europe since the beginning of the 20th century. In recent years this tree hole breeding mosquito spe
Rapid and accurate detection of <em>Mycobacterium tuberculosis</em> in sputum samples by Cepheid Xpert MTB/RIF assay - a clinical validation study (Publications)
BACKGROUND: A crucial impediment to global tuberculosis control is the lack of an accurate, rapid diagnostic test for detection of patients with active TB. A new, rapid diagnostic method, (Cepheid) Xp
Dynamics of <em>Schistosoma haematobium</em> egg output and associated infection parameters following treatment with praziquantel in school-aged... (Publications)
ABSTRACT: BACKGROUND: Praziquantel is the drug of choice in preventive chemotherapy targeting schistosomiasis. Increasing large-scale administration of praziquantel requires monitoring of drug efficac
Improving community coverage of oral cholera mass vaccination campaigns: lessons learned in Zanzibar (Publications)
BACKGROUND: Recent research in two cholera-endemic communities of Zanzibar has shown that a majority (?94%) of the adult population was willing to receive free oral cholera vaccines (OCVs). Since OCV
Specificity of human immunodeficiency virus (LAV/HTLV-III)-reactive antibodies in African sera from southeastern Tanzania (Publications)
The prevalence of antibodies to human immunodeficiency virus (HIV = LAV/HTLV-III) in a rural population from the Ifakara area in southeastern Tanzania was investigated. Sera from 286 individuals colle
Simulation of the cost-effectiveness of malaria vaccines (Publications)
BACKGROUND: A wide range of possible malaria vaccines is being considered and there is a need to identify which vaccines should be prioritized for clinical development. An important element of the inf