Trematocidal activity of praziquantel and artemisinin derivatives:<em> in vitro</em> and <em>in vivo</em> investigations with adult <em>Echinostoma... (Publications)
We examined the effects of praziquantel and the artemisinins on adult Echinostoma caproni. In vitro, both praziquantel and the artemisinins exhibited exposure-response relationships. In vivo, worm bur
Update on the diagnosis and treatment of food-borne trematode infections (Publications)
PURPOSE OF REVIEW: More than 40 million people are affected by food-borne trematode infections. Diagnosis is unsatisfactory and there are only two drugs available for treatment and control: praziquant
<em>Fasciola hepatica</em>: tegumental alterations in adult flukes following in vitro and in vivo administration of artesunate and artemether (Publications)
The tegumental changes in adult Fasciola hepatica induced by artemether and artesunate were assessed utilizing scanning electron microscopy (SEM). F hepatica were incubated with artemether and artesun
Effect of artemether, artesunate, OZ78, praziquantel, and tribendimidine alone or in combination chemotherapy on the tegument of <em>Clonorchis... (Publications)
We investigated the morphological effects of half-strength treatments with praziquantel, artemether, artesunate, OZ78 and tribendimidine as well as combinations of praziquantel with artemether, artesu
Activity of artemether and OZ78 against triclabendazole-resistant <em>Fasciola hepatica</em> (Publications)
Triclabendazole is the drug of choice against Fasciola hepatica infections in humans and animals. However, parasite resistance against triclabendazole is spreading in the veterinary field, and there a