Asthma, COPD and overlap syndrome: a longitudinal study in young European adults (Publications)
We compared risk factors and clinical characteristics, 9-year lung function change and hospitalisation risk across subjects with the asthma-chronic obstructive pulmonary disease (COPD) overlap syndrom
Association between ambient air pollution and diabetes mellitus in Europe and North America: systematic review and meta-analysis (Publications)
BACKGROUND: Air pollution is hypothesized to be a risk factor for diabetes. Epidemiological evidence is inconsistent and has not been systematically evaluated. OBJECTIVES: We systematically reviewed e
Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort (Publications)
Although evidence for the heterogeneity of asthma accumulated, consensus for definitions of asthma phenotypes is still lacking. Obesity may have heterogeneous effects on various asthma phenotypes. We
Adult onset asthma and interaction between genes and active tobacco smoking: the GABRIEL consortium (Publications)
BACKGROUND: Genome-wide association studies have identified novel genetic associations for asthma, but without taking into account the role of active tobacco smoking. This study aimed to identify nove
Air pollution from road traffic and systemic inflammation in adults: a cross-sectional analysis in the European ESCAPE project (Publications)
BACKGROUND: Exposure to particulate matter air pollution (PM) has been associated with cardiovascular diseases. OBJECTIVES: This study evaluated whether annual exposure to ambient air pollution is ass
Particulate matter and subclinical atherosclerosis: associations between different particle sizes and sources with carotid intima-media thickness in... (Publications)
BACKGROUND: Subclinical atherosclerosis has been associated with long-term exposure to particulate matter (PM), but the relevance of particle size and sources of exposure remains unclear. OBJECTIVES:
Air pollution, climate and pollen comparisons in urban, rural and alpine regions in Switzerland (Publications)
The aim of this paper is to show spatial differences and correlations in long- term air pollution measurements in the eight SAPALDIA sites (Swiss Study on Air Pollution and Lung Diseases in Adults, SA
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (Publications)
HapMap imputed genome-wide association studies (GWAS) have revealed > 50 loci at which common variants with minor allele frequency > 5% are associated with kidney function. GWAS using more complete re
Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)
OBJECTIVE: Inflammatory risk factors in childhood, e.g. obesity, impact on carotid artery intima media thickness (CIMT), an early indicator of atherosclerosis. Little is known on potential infectious