Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate (Publications)
Fascioliasis is a zoonotic disease of considerable public health and great veterinary significance and new drugs are needed. OZ78 is a promising fasciocidal drug candidate. In order to support the dev
Cupiennin 1a exhibits a remarkably broad, non-stereospecific cytolytic activity on bacteria, protozoan parasites, insects, and human cancer cells (Publications)
Cupiennin 1a, a cytolytic peptide isolated from the venom of the spider Cupiennius salei, exhibits broad membranolytic activity towards bacteria, trypanosomes, and plasmodia, as well as human blood an
Wirkungen von Stickstoffdioxid auf die menschliche Gesundheit - Ableitung eines gesundheitsbezogenen Kurz - und Langzeitgrenzwertes (Publications)
Effects of nitrogen dioxide on human health - Derivation of a health related short- and long-term value. The presented overview concerning health relevant effects caused by nitrogen dioxide resumes th
FLOTAC: a promising technique for detecting helminth eggs in human faeces (Publications)
There is a tendency to neglect diagnostic issues in the era of 'preventive chemotherapy' in human helminthiases. However, accurate diagnosis cannot be overemphasized for adequate patient management an
Impact of a single exercise bout on energy expenditure and spontaneous physical activity of obese boys (Publications)
The main objective of the present study was to determine whether a structured, laboratory-based exercise task would modify the energy expenditure (EE) and the pattern of spontaneous physical activity
Soil-transmitted helminth infections and risk factors in preschool children in southern rural Lao People's Democratic Republic (Publications)
The current widespread school-based control of soil-transmitted helminth (STH) infections is also advocated for preschool children. The objective of this study was to assess infection with STHs as wel
Global metabolic responses of NMRI mice to an experimental <em>Plasmodium berghei</em> infection (Publications)
We present a metabolism-driven top-down systems biology approach to characterize metabolic changes in the mouse resulting from an infection with Plasmodium berghei, using high-resolution (1)H NMR spec