Optimization of triazine nitriles as rhodesain inhibitors: structure-activity relationships, bioisosteric imidazopyridine nitriles, and X-ray crystal... (Publications)
The cysteine protease rhodesain of Trypanosoma brucei parasites causing African sleeping sickness has emerged as a target for the development of new drug candidates. Based on a triazine nitrile moiety
Discordances in the application of different criteria for quantification of paediatric abdominal obesity: an analysis of two Swiss studies (Publications)
Several definitions of paediatric abdominal obesity have been proposed but it is unclear whether they lead to similar results. We assessed the prevalence of abdominal obesity using five different wais
Sexualité et SIDA: étude CAPC réalisée en 1989 en milieu scolaire à Ouagadougou (Burkina Faso) (Publications)
AIDS is nowadays one of the major problems of public health in Burkina Faso. In order to get informations on pupils' sexual behaviour and knowledge about AIDS, we conducted a study on a representative
Epidemiology of schistosomiasis in two high-risk communities of south Côte d'Ivoire with particular emphasis on pre-school-aged children (Publications)
Schistosomiasis control efforts mainly target school-aged children. We studied the epidemiology of schistosomiasis in two high-risk communities in south Cote d'Ivoire, placing particular emphasis on p
A prospective study of the impact of air pollution on respiratory symptoms and infections in infants (Publications)
Rationale: There is increasing evidence that short-term exposure to air pollution has a detrimental effect on respiratory health, but data from healthy populations, particularly infants, are scarce. O
3-(oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid <em>Trypanosoma brucei</em>, the causative agent... (Publications)
A whole organism high-throughput screen of approximately 87,000 compounds against Trypanosoma brucei brucei led to the recent discovery of several novel compound classes with low micromolar activity a
Indifferent to disease: a qualitative investigation of the reasons why some Papua New Guineans who own mosquito nets choose not to use them (Publications)
This paper presents findings from a qualitative study designed to explore the reasons why some Papua New Guineans who own mosquito nets choose not to use them, whether on a regular or episodic basis.
Mould and dampness in dwelling places, and onset of asthma: the population-based cohort ECRHS (Publications)
OBJECTIVES: To study new onset of adult asthma in relation to dampness and moulds in dwelling places. METHODS: Totally, 7104 young adults from 13 countries who participated in the European Community R