N-oxide alkaloids from <em>Crinum amabile</em> (Amaryllidaceae) (Publications)
Natural products play an important role in the development of new drugs. In this context, the Amaryllidaceae alkaloids have attracted considerable attention in view of their unique structural features
Do bednets including piperonyl butoxide offer additional protection against populations of<em> Anopheles gambiae s.l. </em>that are highly resistant... (Publications)
Malaria control is dependent on the use of longlasting insecticidal nets (LLINs) containing pyrethroids. A new generation of LLINs containing both pyrethroids and the synergist piperonyl butoxide (PBO
Spatial PM2.5, NO2, O3 and BC models for Western Europe - evaluation of spatiotemporal stability (Publications)
BACKGROUND: In order to investigate associations between air pollution and adverse health effects consistent fine spatial air pollution surfaces are needed across large areas to provide cohorts with c
Are schoolchildren less infected if they have good knowledge about parasitic worms? A case study from rural Côte d'Ivoire (Publications)
BACKGROUND: Parasitic worms (helminths) are common infections in low- and middle-income countries. For most helminth species, school-aged children are at highest risk of infection and morbidity, such
Population pharmacokinetics of the antimalarial amodiaquine: a pooled analysis to optimize dosing (Publications)
Amodiaquine plus artesunate is the recommended antimalarial treatment in many malaria-endemic countries. However, pediatric doses are largely based on a linear extrapolation from adult doses. We poole
Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions (Publications)
Objectives: We evaluated whether dried blood spots (DBS) are suitable to monitor combined ART when samples are collected in rural Tanzania and transported over a long distance to a specialized bioanal