Efficacy of single versus four repeated doses of praziquantel agains<em>t Schistosoma mansoni </em>infection in school-aged children from Côte... (Publications)
BACKGROUND: Preventive chemotherapy with praziquantel (PZQ) is the cornerstone of schistosomiasis control. However, a single dose of PZQ (40 mg/kg) does not cure all infections. Repeated doses of PZQ
Activity of diphenyl ether benzyl amines against human African trypanosomiasis (Publications)
Insect-borne parasite Trypanosoma brucei plagues humans and other animals, eliciting the disease Human African trypanosomiasis, also known as African sleeping sickness. This disease poses the biggest
Molecular detection of <em>Rickettsia </em>spp., <em>Borrelia </em>spp., <em>Bartonella </em>spp. and <em>Yersinia pestis</em> in ectoparasites of... (Publications)
Little is known about the presence of vector-borne bacteria in southwest Madagascar. Anthropogenic alteration of natural habitats represents an important driver for the emergence of new diseases. Espe
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age (Publications)
BACKGROUND: Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal develop
Prevalence and predictors of residual antibiotics in children's blood in community settings in Tanzania (Publications)
OBJECTIVE: Children account for a significant proportion of antibiotic consumption in low- and middle-income countries, with overuse occurring in formal and informal health sectors. This study assesse
Severe outcomes of malaria in children under time-varying exposure (Publications)
In malaria epidemiology, interpolation frameworks based on available observations are critical for policy decisions and interpreting disease burden. Updating our understanding of the empirical evidenc
Multiplex PCR for bacterial, viral and protozoal pathogens in persistent diarrhoea or persistent abdominal pain in Côte d'Ivoire, Mali and Nepal (Publications)
In contrast to acute diarrhoea, the aetiology of persistent digestive disorders (≥ 14 days) is poorly understood in low-resource settings and conventional diagnostic approaches lack accuracy. In this
Seroprevalence of <em>Rickettsia</em> Spp. and <em>Orientia tsutsugamushi</em> in indigenous populations from the Sierra Nevada de Santa Marta,... (Publications)
Background: Rickettsia spp. are vector-borne zoonotic pathogens that cause febrile illness in humans. Rickettsioses is not included in the Colombian national surveillance system and is subsequently ex
Rising rural body-mass index is the main driver of the global obesity epidemic in adults (Publications)
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(1,2). This has led to a widely reported view that urbaniza
Preparation of sesquiterpene lactone-loaded PLA nanoparticles and evaluation of their antitrypanosomal activity (Publications)
Human African trypanosomiasis (HAT), also commonly known as sleeping sickness, is a neglected tropical disease affecting millions of people in poorly developed regions in sub-Saharan Africa. There is