Identification of lymphogranuloma venereum-associated <em>Chlamydia trachomatis</em> serovars by fluorescence <em>in situ</em> hybridisation--a... (Publications)
We describe a proof-of-principle evaluation of a fluorescence in situ hybridisation (FISH) procedure to identify Chlamydia trachomatis serovars L1-L3, the causative agents of lymphogranuloma venereum,
Regional differences and trends in breast cancer surgical procedures and their relation to socioeconomic disparities and screening patterns (Publications)
BackgroundImportant regional disparities in patterns of care in breast cancer have recently been described. In Switzerland,nationwide data on hospitalisations have been collected since 1998. They have
A multiplex qPCR approach for detection of <em>pfhrp2 </em>and <em>pfhrp3</em> gene deletions in multiple strain infections of <em>Plasmodium... (Publications)
The rapid and accurate diagnosis of Plasmodium falciparum malaria infection is an essential factor in malaria control. Currently, malaria diagnosis in the field depends heavily on using rapid diagnost
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in <em>Plasmodium falciparum</em> (Publications)
Malaria eradication is critically dependent on new therapeutics that target resistant Plasmodium parasites and block transmission of the disease. Here, we report that pantothenamide bioisosteres were
The genetic background modulates the evolution of fluoroquinolone-resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Fluoroquinolones (FQ) form the backbone in experimental treatment regimens against drug-susceptible tuberculosis. However, little is known on whether the genetic variation present in natural populatio
Prevalence and management of drug-drug interactions with antiretroviral treatment in 2069 people living with HIV in rural Tanzania: a prospective... (Publications)
OBJECTIVES: Widespread access to antiretroviral therapy (ART) has substantially increased life expectancy in sub-Saharan African countries. As a result, the rates of comorbidities and use of co-medica
The molecular clock of <em>Mycobacterium tuberculosis</em> (Publications)
The molecular clock and its phylogenetic applications to genomic data have changed how we study and understand one of the major human pathogens, Mycobacterium tuberculosis (MTB), the etiologic agent o