Pooled population pharmacokinetic analysis of tribendimidine for the treatment of <em>Opisthorchis viverrini</em> infections (Publications)
Opisthorchiasis, caused by the food-borne trematode Opisthorchis viverrini, affects more than 8 million people in Southeast Asia. In the framework of a phase 2b clinical trial conducted in Lao PDR, ph
Association of ambient air pollution with lengths of hospital stay for Hanoi children with acute lower-respiratory infection, 2007-2016 (Publications)
INTRODUCTION: The association between ambient air pollution and length of hospital stay (LOS) for children with lower-respiratory infection is unclear. MATERIALS AND METHODS: The association was exami
Resistance to Artemisinin Combination Therapies (ACTs): do not forget the partner drug! (Publications)
Artemisinin-based combination therapies (ACTs) have become the mainstay for malaria treatment in almost all malaria endemic settings. Artemisinin derivatives are highly potent and fast acting antimala
Lifetime economic impact of the burden of childhood stunting attributable to maternal psychosocial risk factors in 137 low/middle-income countries (Publications)
Introduction: The first 1000 days of life is a period of great potential and vulnerability. In particular, physical growth of children can be affected by the lack of access to basic needs as well as p
Metabolism of (<em>R</em>)-praziquantel versus the activation of a Parasite Transient Receptor Potential Melastatin ion channel (Publications)
Praziquantel (PZQ) is an essential anthelmintic drug recently established to be an activator of a Transient Receptor Potential Melastatin (TRPM(PZQ) ) ion channel in trematode worms. Bioinformatic, mu
Opportunities and challenges for decentralised clinical trials in sub-Saharan Africa: a qualitative study (Publications)
INTRODUCTION: Digital health has gained traction in research and development, and clinical decision support systems. The COVID-19 pandemic accelerated the adoption of decentralised clinical trials (DC
Antibody and B cell responses to SARS-CoV-2 infection and vaccination: the end of the beginning (Publications)
As the COVID-19 pandemic has evolved during the past years, interactions between human immune systems, rapidly mutating and selected SARS-CoV-2 viral variants, and effective vaccines have complicated