Simulation of the cost-effectiveness of malaria vaccines (Publications)
BACKGROUND: A wide range of possible malaria vaccines is being considered and there is a need to identify which vaccines should be prioritized for clinical development. An important element of the inf
Laboratory and field trials at Ifakara (Kilombero District, Tanzania) on the plant molluscicide <em>Swartzia madagascariensis</em> (Publications)
The molluscicidal activity of crushed seed pods of Swartzia madagascariensis was assessed by laboratory and field trials. Mature dry seed pods were ground and extracted in tap water for 24 h. Water ex
Improved protective efficacy of a species-specific DNA vaccine encoding mycolyl-transferase Ag85A from <em>Mycobacterium ulcerans</em> by homologous... (Publications)
Vaccination with plasmid DNA encoding Ag85A from M. bovis BCG can partially protect C57BL/6 mice against a subsequent footpad challenge with M. ulcerans. Unfortunately, this cross-reactive protection
Molecular characterization of <em>Mycobacterium bovis</em> strains isolated from cattle slaughtered at two abattoirs in Algeria (Publications)
BACKGROUND: Bovine Tuberculosis is prevalent in Algeria despite governmental attempts to control the disease. The objective of this study was to conduct, for the first time, molecular characterization
Costs of illness due to cholera, costs of immunization and cost-effectiveness of an oral cholera mass vaccination campaign in Zanzibar (Publications)
BACKGROUND: The World Health Organization (WHO) recommends oral cholera vaccines (OCVs) as a supplementary tool to conventional prevention of cholera. Dukoral, a killed whole-cell two-dose OCV, was us
Development of a temperature-switch PCR-based SNP typing method for <em>Mycobacterium ulcerans</em> (Publications)
Mycobacterium ulcerans (M. ulcerans), the causative agent of the devastating skin disease Buruli ulcer (BU), is characterized by an extremely low level of genetic diversity. Recently, we have reported