Rapid identification of paragonimiasis foci<em> </em>by lay informants in Lao People's Democratic Republic (Publications)
BACKGROUND: Paragonimiasis is a food-borne trematodiasis leading to lung disease. Worldwide, an estimated 21 million people are infected. Foci of ongoing transmission remain often unnoticed. We evalua
Potential benefits, limitations and target product-profiles of odor-baited mosquito traps for malaria control in Africa (Publications)
BACKGROUND: Traps baited with synthetic human odors have been proposed as suitable technologies for controlling malaria and other mosquito-borne diseases. We investigated the potential benefits of suc
Influence of <em>M. tuberculosis</em> lineage variability within a clinical trial for pulmonary tuberculosis (Publications)
Recent studies suggest that M. tuberculosis lineage and host genetics interact to impact how active tuberculosis presents clinically. We determined the phylogenetic lineages of M. tuberculosis isolate
Comparative genomics of metabolic networks of free-living and parasitic eukaryotes (Publications)
BACKGROUND: Obligate endoparasites often lack particular metabolic pathways as compared to free-living organisms. This phenomenon comprises anabolic as well as catabolic reactions. Presumably, the cor
Molecular characterisation of <em>Mycobacterium bovis</em> isolated from cattle slaughtered at the Bamako abattoir in Mali (Publications)
Background: Mali is one of the most important livestock producers of the Sahel region of Africa. A high frequency of bovine tuberculosis (BTB) has been reported but surveillance and control schemes ar
Spatial risk profiling of <em>Plasmodium falciparum</em> parasitaemia in a high endemicity area in Côte d'Ivoire (Publications)
BACKGROUND: The objective of this study was to identify demographic, environmental and socioeconomic risk factors and spatial patterns of Plasmodium falciparum parasitaemia in a high endemicity area o
What should vaccine developers ask? Simulation of the effectiveness of malaria vaccines (Publications)
BACKGROUND: A number of different malaria vaccine candidates are currently in pre-clinical or clinical development. Even though they vary greatly in their characteristics, it is unlikely that any of t
Malaria: a major health problem within an oil palm plantation around Popondetta, Papua New Guinea (Publications)
BACKGROUND: For companies operating in malaria endemic countries, malaria represents a substantial risk to workers and their dependants, and can lead to significantly reduced worker productivity. This