<em>Plasmodium vivax</em> and <em>Plasmodium falciparum</em> infection dynamics: re-infections, recrudescences and relapses (Publications)
BACKGROUND: In malaria endemic populations, complex patterns of Plasmodium vivax and Plasmodium falciparum blood-stage infection dynamics may be observed. Genotyping samples from longitudinal cohort s
Development of dengue virus serotype-specific NS1 capture assays for the rapid and highly sensitive identification of the infecting serotype in human... (Publications)
Dengue fever can be caused by one of four distinct dengue virus (DENV) serotypes that cocirculate in many parts of the world. Point of care serotype-specific nonstructural protein-1 (NS1) capture assa
If you can't measure it- you can't change it - a longitudinal study on improving quality of care in hospitals and health centers in rural... (Publications)
BACKGROUND: The Kenyan Ministry of Health- Department of Standards and Regulations sought to operationalize the Kenya Quality Assurance Model for Health. To this end an integrated quality management s
Biological evaluation and x-ray co-crystal structures of cyclohexylpyrrolidine ligands for trypanothione reductase, an enzyme from the redox... (Publications)
The tropical diseases human African trypanosomiasis, Chagas disease, and the various forms of leishmaniasis are caused by parasites of the family of trypanosomatids. These protozoa possess a unique re
GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing (Publications)
Malaria is caused by Plasmodium parasites that proliferate in the bloodstream. During each replication cycle, some parasites differentiate into gametocytes, the only forms able to infect the mosquito
Incomplete<em> Plasmodium falciparum</em> growth inhibition following piperaquine treatment translates into increased parasite viability in the <em>in... (Publications)
Antimalarial resistance to the first-line partner drug piperaquine (PPQ) threatens the effectiveness of artemisinin-based combination therapy. In vitro piperaquine resistance is characterized by incom
Association between concurrence of multiple risk factors and under-5 mortality: a pooled analysis of data from demographic and health survey in 61... (Publications)
BACKGROUND: Exposure to multiple risk factors is prevalent in low-and middle-income countries (LMICs), challenging one-directional strategies to address preventable under-5 mortality (U5M). This study