Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in <em>Plasmodium falciparum</em> (Publications)
Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived
Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial (Publications)
BACKGROUND: Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine. This trial was the firs
Analysing and recommending options for maintaining universal coverage with long-lasting insecticidal nets: the case of Tanzania in 2011 (Publications)
BACKGROUND: Tanzania achieved universal coverage with long-lasting insecticidal nets (LLINs) in October 2011, after three years of free mass net distribution campaigns and is now faced with the challe
Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change (Publications)
ABSTRACT: BACKGROUND: A sound understanding of malaria transmission patterns in the People's Republic of China (P.R. China) is crucial for designing effective surveillance-response strategies that can
Scaling up antiretroviral therapy in Uganda: Using supply chain management to appraise health systems strengthening (Publications)
ABSTRACT: BACKGROUND: Strengthened national health systems are necessary for effective and sustained expansion of antiretroviral therapy (ART). ART and its supply chain management in Uganda are largel
Secondary Buruli ulcer skin lesions emerging several months after completion of chemotherapy: paradoxical reaction or evidence for immune protection? (Publications)
BACKGROUND: The neglected tropical disease Buruli ulcer (BU) caused by Mycobacterium ulcerans is an infection of the subcutaneous tissue leading to chronic ulcerative skin lesions. Histopathological f
Elimination of tropical disease through surveillance and response [Editorial] (Publications)
Surveillance and response represent the final crucial steps in achieving effective control and particularly elimination of communicable diseases as recognized in the area of neglected tropical disease
Costs and cost-effectiveness of vector control in Eritrea using insecticide-treated bed nets (Publications)
BACKGROUND: While insecticide-treated nets (ITNs) are a recognized effective method for preventing malaria, there has been an extensive debate in recent years about the best large-scale implementation