Moxi Strong - Moxidectin for Strongyloidiasis
Project Abstract
The overarching goal of this project is to assemble for the first time key data on the safety and efficacy and pharmacokinetics of moxidectin for the treatment of strongyloidiasis. We propose to conduct a Phase 2a The project consists of three objectives:
1. What is the efficacy and safety of ascending moxidectin doses (2-12 mg versus placebo) against S. stercoralis infections in adults?
2. Can dried blood spots be used to analyse pharmacokinetic (PK) properties of moxidectin?
3. What are the key PK parameters of moxidectin in patients infected with S. stercoralis?
