Publications

Day C.J, Favuzza P, Bielfeld S, Haselhorst T, Seefeldt L, Hauser J, Shewell L.K, Flück C, Poole J, Jen F.E.-C, Schäfer A, Dangy J.-P, Gilberger T.-W, França C.T, Duraisingh M.T, Tamborrini M, Brancucci N.M.B, Grüring C, Filarsky M, Jennings M.P, Pluschke G. The essential malaria protein PfCyRPA targets glycans to invade erythrocytes. Cell Rep. 2024;43(4):114012. DOI: 10.1016/j.celrep.2024.114012

Tamborrini M, Schäfer A, Hauser J, Zou L, Paris D.H, Pluschke G. The malaria blood stage antigen PfCyRPA formulated with the TLR-4 agonist adjuvant GLA-SE elicits parasite growth inhibitory antibodies in experimental animals. Malar J. 2023;22:210. DOI: 10.1186/s12936-023-04638-8

Fernandes B, Sousa M, Castro R, Schäfer A, Hauser J, Schulze K, Amacker M, Tamborrini M, Pluschke G, Alves P.M, Fleury S, Roldão A. Scalable process for high-yield production of PfCyRPA using insect cells for inclusion in a malaria virosome-based vaccine candidate. Front Bioeng Biotechnol. 2022;10:879078. DOI: 10.3389/fbioe.2022.87907

Tamborrini M, Hauser J, Schäfer A, Amacker M, Favuzza P, Kyungtak K, Fleury S, Pluschke G. Vaccination with virosomally formulated recombinant CyRPA elicits protective antibodies against Plasmodium falciparum parasites in preclinical in vitro and in vivo models. Vaccines. 2020;5:9. DOI: 10.1038/s41541-020-0158-9

Lamelas A, Hamid A.M, Dangy J.P, Hauser J, Jud M, Röltgen K, Hodgson A, Junghanss T, Harris S.R, Parkhill J, Bentley S.D, Pluschke G. Loss of genomic diversity in a Neisseria meningitidis clone through a colonization bottleneck. Genome Biol Evol. 2018;10(8):2102-2109. DOI: 10.1093/gbe/evy152

Lamelas A, Hauser J, Dangy J.P, Hamid A.M, Roltgen K, Abdul Sater M.R, Hodgson A, Sie A, Junghanss T, Harris S.R, Parkhill J, Bentley S.D, Pluschke G. Emergence and genomic diversification of a virulent serogroup W:ST-2881(CC175) Neisseria meningitidis clone in the African meningitis belt. Microb Genom. 2017;3(8):e000120. DOI: 10.1099/mgen.0.000120

Kpeli G, Owusu-Mireku E, Hauser J, Hinic V, Danso E, Frei R, Pluschke G, Yeboah-Manu D. Extended spectrum beta lactam resistance among gram negative bacterial isolates from wounds of patients attending a Ghanaian Hospital. Trop Med Int Health, 2015;20(Suppl. 1):155

Tamborrini M, Geib N, Marrero-Nodarse A, Jud M, Hauser J, Aho C, Lamelas A, Zuniga A, Pluschke G, Ghasparian A, Robinson J.A. A synthetic virus-like particle streptococcal vaccine candidate using B-cell epitopes from the proline-rich region of pneumococcal surface protein A. Vaccine. 2015;3(4):850-874. DOI: 10.3390/vaccines3040850

Koeberling O, Ispasanie E, Hauser J, Rossi O, Pluschke G, Caugant D.A, Saul A, MacLennan C.A. A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalised modules for membrane antigens (GMMA). Vaccine. 2014;32(23):2688-2695. DOI: 10.1016/j.vaccine.2014.03.068

Lamelas A, Harris S.R, Röltgen K, Dangy J.P, Hauser J, Kingsley R.A, Connor T.R, Sie A, Hodgson A, Dougan G, Parkhill J, Bentley S.D, Pluschke G. Emergence of a new epidemic Neisseria meningitidis serogroup A clone in the African meningitis belt: high-resolution picture of genomic changes that mediate immune evasion. mBio. 2014;5(5):e01974-14. DOI: 10.1128/mBio.01974-14

Käser M, Hauser J, Pluschke G. PCR typing of Mycobacterium ulcerans lineages based on large sequence polymorphisms. Medical Microbiol Diagnosis. 2012;S1:001. DOI: 10.4172/2161-0703.S1-001

Balanescu S, Kopp P, Gaskill M.B, Morgenthaler N.G, Schindler C, Rutishauser J. Correlation of plasma copeptin and vasopressin concentrations in hypo-, iso-, and hyperosmolar states. J Clin Endocrinol Metab. 2011;96(4):1046-1052. DOI: 10.1210/jc.2010-2499

Käser M, Ruf M.T, Hauser J, Pluschke G. Optimized DNA preparation from mycobacteria. Cold Spring Harb Protoc. 2010;2010(4):pdb.prot5408. DOI: 10.1101/pdb.prot5408

Käser M, Gutmann O, Hauser J, Stinear T, Cole S, Yeboah-Manu D, Dernick G, Certa U, Pluschke G. Lack of insertional-deletional polymorphism in a collection of Mycobacterium ulcerans isolates from Ghanaian Buruli ulcer patients. J Clin Microbiol. 2009;47(11):3640-3646. DOI: 10.1128/JCM.00760-09

Käser M, Hauser J, Pluschke G. Single nucleotide polymorphisms on the road to strain differentiation in Mycobacterium ulcerans. J Clin Microbiol. 2009;47(11):3647-3652. DOI: 10.1128/JCM.00761-09

Käser M, Hauser J, Small P, Pluschke G. Large sequence polymorphisms unveil the phylogenetic relationship of environmental and pathogenic mycobacteria related to Mycobacterium ulcerans. Appl Environ Microbiol. 2009;75(17):5667-5675. DOI: 10.1128/AEM.00446-09

Käser M, Ruf M.T, Hauser J, Marsollier L, Pluschke G. Optimized method for preparation of DNA from pathogenic and environmental mycobacteria. Appl Environ Microbiol. 2009;75(2):414-418