Publications

Probst-Hensch N, Imboden M, Jeong A, Keidel D, Vermes T, Witzig M, Cullati S, Tancredi S, Noor N, Rodondi P.Y, Harju E, Michel G, Frank I, Kahlert C, Cusini A, Rodondi N, Chocano-Bedoya P.O, Bardoczi J.B, Stuber M.J, Vollrath F, Fehr J, Frei A, Kaufmann M, Geigges M, von Wyl V, Puhan M.A, Albanese E, Crivelli L, Lovison G.F, Corona Immunitas Research Group. Long-term trajectories of densely reported depressive symptoms during an extended period of the COVID-19 pandemic in Switzerland: social worries matter. Compr Psychiatry. 2024;130:152457. DOI: 10.1016/j.comppsych.2024.152457

Tancredi S, van der Linden B.W.A, Chiolero A, Cullati S, Imboden M, Probst-Hensch N, Keidel D, Witzig M, Dratva J, Michel G, Harju E, Frank I, Lorthe E, Baysson H, Stringhini S, Kahlert C.R, Bardoczi J.B, Haller M.L, Chocano-Bedoya P.O, Rodondi N, Amati R, Albanese E, Corna L, Crivelli L, Kaufmann M, Frei A, von Wyl V. Socioeconomic status and adherence to preventive measures during the COVID-19 pandemic in Switzerland: a population based digital cohort analysis. Int J Public Health. 2024;69:1606861. DOI: 10.3389/ijph.2024.1606861

Zhai J, Voraphani N, Imboden M, Keidel D, Liu C, Stern D.A, Venker C, Petersen H, Bosco A, Sherrill D.L, Morgan W.J, Tesfaigzi Y, Probst-Hensch N.M, Martinez F.D, Halonen M, Guerra S. Circulating biomarkers of airflow limitation across the life span. J Allergy Clin Immunol. 2024;153(6):1692-1703. DOI: 10.1016/j.jaci.2023.12.026

Daniore P, Moser A, Höglinger M, Probst-Hensch N, Imboden M, Vermes T, Keidel D, Bochud M, Ortega Herrero N, Baggio S, Chocano-Bedoya P, Rodondi N, Tancredi S, Wagner C, Cullati S, Stringhini S, Gonseth Nusslé S, Veys-Takeuchi C, Zuppinger C, Harju E, Michel G, Frank I, Kahlert C.R, Albanese E, Crivelli L, Levati S, Amati R, Kaufmann M, Geigges M, Ballouz T, Frei A, Fehr J, von Wyl V. Interplay of digital proximity app use and SARS-CoV-2 vaccine uptake in Switzerland: analysis of two population-based cohort studies. Int J Public Health. 2023;68:1605812. DOI: 10.3389/ijph.2023.1605812

Harju E, Speierer A, Jungo K.T, Levati S, Baggio S, Tancredi S, Noor N, Rodondi P.Y, Cullati S, Imboden M, Keidel D, Witzig M, Frank I, Kohler P, Kahlert C, Crivelli L, Amati R, Albanese E, Kaufmann M, Frei A, Von Wyl V, Puhan M.A, Probst-Hensch N, Michel G, Rodondi N, Chocano-Bedoya P, Corona Immunitas Res Grp. Changes in healthcare utilization during the COVID-19 pandemic and potential causes : a cohort study from Switzerland. Int J Public Health. 2023;68:1606010. DOI: 10.3389/ijph.2023.1606010

Markevych I, Zhao T, Fuertes E, Marcon A, Dadvand P, Vienneau D, Garcia Aymerich J, Nowak D, de Hoogh K, Jarvis D, Abramson M.J, Accordini S, Amaral A.F, Bentouhami H, Jacobsen Bertelsen R, Boudier A, Bono R, Bowatte G, Casas L, Dharmage S.C, Forsberg B, Gislason T, Gnesi M, Holm M, Jacquemin B, Janson C, Jogi R, Johannessen A, Keidel D, Leynaert B, Maldonado Perez J.A, Marchetti P, Migliore E, Martínez-Moratalla J, Orru H, Pin I, Potts J, Probst-Hensch N, Ranzi A, Sánchez-Ramos J.L, Siroux V, Soussan D, Sunyer J, Urrutia Landa I, Villani S, Heinrich J. Residential greenspace and lung function decline over 20 years in a prospective cohort: the ECRHS study. Environ Int. 2023;178:108036. DOI: 10.1016/j.envint.2023.108036

Probst-Hensch N, Jeong A, Keidel D, Imboden M, Lovison G. Depression trajectories during the COVID-19 pandemic in the high-quality health care setting of Switzerland: the COVCO-Basel cohort. Public Health. 2023;217:65-73. DOI: 10.1016/j.puhe.2023.01.010

Sabatini S, Kaufmann M, Fadda M, Tancredi S, Noor N, Van Der Linden B.W.A, Cullati S, Frank I, Michel G, Harju E, Luedi C, Frei A, Ballouz T, Menges D, Fehr J, Kohler P, Kahlert C.R, Scheu V, Ortega N, Chocano-Bedoya P, Rodondi N, Stringhini S, Baysson H, Lorthe E, Zufferey M.C, Suggs L.S, Albanese E, Vincentini J, Bochud M, D'Acremont V, Nusslé S.G, Imboden M, Keidel D, Witzig M, Probst-Hensch N, von Wyl V. Factors associated with COVID-19 non-vaccination in Switzerland: a nationwide study. Int J Public Health. 2023;68:1605852. DOI: 10.3389/ijph.2023.1605852

Tancredi S, Chiolero A, Wagner C, Haller M.L, Chocano-Bedoya P, Ortega N, Rodondi N, Kaufmann L, Lorthe E, Baysson H, Stringhini S, Michel G, Ludi C, Harju E, Frank I, Imboden M, Witzig M, Keidel D, Probst-Hensch N, Amati R, Albanese E, Corna L, Crivelli L, Vincentini J, Gonseth Nussle S, Bochud M, D'Acremont V, Kohler P, Kahlert C.R, Cusini A, Frei A, Puhan M.A, Geigges M, Kaufmann M, Fehr J, Cullati S, Corona Immunitas Research Group. Seroprevalence trends of anti-SARS-CoV-2 antibodies and associated risk factors: a population-based study. Infection. 2023;51(5):1453-1465. DOI: 10.1007/s15010-023-02011-0

Tancredi S, Ulyte A, Wagner C, Keidel D, Witzig M, Imboden M, Probst-Hensch N, Amati R, Albanese E, Levati S, Crivelli L, Kohler P, Cusini A, Kahlert C, Harju E, Michel G, Ludi C, Ortega N, Baggio S, Chocano-Bedoya P, Rodondi N, Ballouz T, Frei A, Kaufmann M, Von Wyl V, Lorthe E, Baysson H, Stringhini S, Schneider V, Kaufmann L, Wieber F, Volken T, Zysset A, Dratva J, Cullati S, Corona Immunitas Research Group. Changes in socioeconomic resources and mental health after the second COVID-19 wave (2020-2021): a longitudinal study in Switzerland. Int J Equity Health. 2023;22:51. DOI: 10.1186/s12939-023-01853-2

Jeong A, Eze I.C, Vienneau D, de Hoogh K, Keidel D, Rothe T, Burdet L, Holloway J.W, Jarvis D, Kronenberg F, Lovison G, Imboden M, Probst-Hensch N. Residential greenness-related DNA methylation changes. Environ Int. 2022;158:106945. DOI: 10.1016/j.envint.2021.106945

Jeong A, Galliker F, Imboden M, Keidel D, de Hoogh K, Vienneau D, Siegrist M, Crivelli L, Lovison G, Probst-Hensch N. Residential exposure to greenspace and life satisfaction in times of COVID-19: a cross-sectional analysis of 9444 participants from a population-based study in Basel-Stadt and Basel-Landschaft. Swiss Med Wkly. 2022;152:w30204. DOI: 10.4414/smw.2022.w30204

Speierer A, Chocano-Bedoya P.O, Anker D, Schmid A, Keidel D, Vermes T, Imboden M, Levati S, Franscella G, Corna L, Amati R, Harju E, Luedi C, Michel G, Veys-Takeuchi C, Zuppinger C, Nussle S.G, D'Acremont V, Tall I, Salberg E, Baysson H, Lorthe E, Pennacchio F, Frei A, Kaufmann M, Geigges M, West E.A, Schwab N, Cullati S, Chiolero A, Kahlert C, Stringhini S, Vollrath F, Probst-Hensch N, Rodondi N, Puhan M.A, von Wyl V. The Corona Immunitas Digital Follow-Up eCohort to monitor impacts of the SARS-CoV-2 pandemic in Switzerland: study protocol and first results. Int J Public Health. 2022;67:1604506. DOI: 10.3389/ijph.2022.1604506

Cerletti P, Eze I.C, Keidel D, Schaffner E, Stolz D, Gasche-Soccal P.M, Rothe T, Imboden M, Probst-Hensch N. Perceived built environment, health-related quality of life and health care utilization. PLoS One. 2021;16(5):e0251251. DOI: 10.1371/journal.pone.0251251

Keidel D, Vermes T, Witzig M, Jeong A, Galliker F, Tertemiz E, Schaffner E, de Hoogh K, Pärli K, Lovison G, Imboden M, Probst-Hensch N. COVCO-Basel - Corona Immunitas: Wissenschaftlicher Schlussbericht - Juli 2020 bis August 2021. Basel: Swiss Tropical and Public Health Institute, 2021

Lytras T, Beckmeyer-Borowko A, Kogevinas M, Kromhout H, Carsin A.E, Anto J.M, Bentouhami H, Weyler J, Heinrich J, Nowak D, Urrutia I, Martinez-Moratalla J, Gullon J.A, Pereira Vega A, Raherison Semjen C, Pin I, Demoly P, Leynaert B, Villani S, Gislason T, Svanes O, Holm M, Forsberg B, Norback D, Mehta A.J, Keidel D, Vernez D, Benke G, Jogi R, Toren K, Sigsgaard T, Schlunssen V, Olivieri M, Blanc P.D, Watkins J, Bono R, Squillacioti G, Buist A.S, Vermeulen R, Jarvis D, Probst-Hensch N, Zock J.P. Cumulative occupational exposures and lung function decline in two large general population cohorts. Ann Am Thorac Soc. 2021;18(2):238-246. DOI: 10.1513/AnnalsATS.202002-113OC

Accordini S, Calciano L, Marcon A, Pesce G, Anto J.M, Beckmeyer-Borowko A.B, Carsin A.E, Corsico A.G, Imboden M, Janson C, Keidel D, Locatelli F, Svanes C, Burney P.G.J, Jarvis D, Probst-Hensch N.M, Minelli C. Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study. Sci Rep. 2020;10:3452. DOI: 10.1038/s41598-020-60478-5

Carsin A.E, Keidel D, Fuertes E, Imboden M, Weyler J, Nowak D, Heinrich J, Pascual Erquicia S, Martinez-Moratalla J, Huerta I, Sanchez J.L, Schaffner E, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Leynaert B, Cerveri I, Squillacioti G, Accordini S, Gislason T, Svanes C, Toren K, Forsberg B, Janson C, Jogi R, Emtner M, Gomez Real F, Jarvis D, Guerra S, Dharmage S.C, Probst-Hensch N, Garcia-Aymerich J. Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of two population-based cohorts. Am J Epidemiol. 2020;89(12):1521-1528. DOI: 10.1093/aje/kwaa087

Cerletti P, Keidel D, Imboden M, Schindler C, Probst-Hensch N. The modifying role of physical activity in the cross-sectional and longitudinal association of health-related quality of life with physiological functioning-based latent classes and metabolic syndrome. Health Qual Life Outcomes. 2020;18:345. DOI: 10.1186/s12955-020-01557-z

Fawcett K.A, Obeidat M, Melbourne C, Shrine N, Guyatt A.L, John C, Luan J, Richmond A, Moksnes M.R, Granell R, Weiss S, Imboden M, May-Wilson S, Hysi P, Boutin T.S, Portas L, Flexeder C, Harris S.E, Wang C.A, Lyytikainen L.P, Palviainen T, Foong R.E, Keidel D, Minelli C, Langenberg C, Bosse Y, Van den Berge M, Sin D.D, Hao K, Campbell A, Porteous D, Padmanabhan S, Smith B.H, Evans D.M, Ring S, Langhammer A, Hveem K, Willer C, Ewert R, Stubbe B, Pirastu N, Klaric L, Joshi P.K, Patasova K, Massimo M, Polasek O, Starr J.M, Karrasch S, Strauch K, Meitinger T, Rudan I, Rantanen T, Pietilainen K, Kahonen M, Raitakari O.T, Hall G.L, Sly P.D, Pennell C.E, Kaprio J, Lehtimaki T, Vitart V, Deary I.J, Jarvis D, Wilson J.F, Spector T, Probst-Hensch N, Wareham N.J, Volzke H, Henderson J, Strachan D.P, Brumpton B.M, Hayward C, Hall I.P, Tobin M.D, Wain L.V. Variants associated with HHIP expression have sex-differential effects on lung function. Wellcome Open Res. 2020;5:111. DOI: 10.12688/wellcomeopenres.15846.1

Carsin A.E, Fuertes E, Schaffner E, Jarvis D, Antó J.M, Heinrich J, Bellisario V, Svanes C, Keidel D, Imboden M, Weyler J, Nowak D, Martinez-Moratalla J, Gullón J.A, Sanchez Ramos J.L, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Cerveri I, Accordini S, Gislason T, Toren K, Forsberg B, Janson C, Jogi R, Emtner M, Gómez Real F, Raza W, Leynaert B, Pascual S, Guerra S, Dharmage S.C, Probst-Hensch N, Garcia-Aymerich J. Restrictive spirometry pattern is associated with low physical activity levels. A population based international study. Respir Med. 2019;146:116-123. DOI: 10.1016/j.rmed.2018.11.017

Hansen S, Zemp E, Bettschart R, Pons M, Rochat T, Jeong A, Keidel D, Schindler C, Probst-Hensch N. Gender differences in the association between life history of body silhouettes and asthma incidence: results from the SAPALDIA cohort study. Respir Med X. 2019;1:100001. DOI: 10.1016/j.yrmex.2019.100001

Keidel D, Anto J.M, Basagana X, Bono R, Burte E, Carsin A.E, Forsberg B, Fuertes E, Galobardes B, Heinrich J, de Hoogh K, Jarvis D, Künzli N, Leynaert B, Marcon A, Le Moual N, de Nazelle A, Schindler C, Siroux V, Stempfelet M, Sunyer J, Temam S, Tsai M.Y, Varraso R, Jacquemin B, Probst-Hensch N. The role of socioeconomic status in the association of lung function and air pollution-a pooled analysis of three adult ESCAPE cohorts. Int J Environ Res Public Health. 2019;16(11):1901. DOI: 10.3390/ijerph16111901

Carsin A.E, Keidel D, Fuertes E, Imboden M, Weyler J, Nowak D, Heinrich J, Urrutia I, Martinez-Moratalla J, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Leynaert B, Cerveri I, Bono R, Accordini S, Amaral A, Gislason T, Svanes C, Toren K, Forsberg B, Janson C, Dharmage S, Jogi R, Anto J, Probst-Hensch N, Garcia-Aymerich J. Physical activity and incidence of restrictive spirometry pattern in adults. Eur Respir J, 2018;52(Suppl. 62):PA5289. DOI: 10.1183/13993003.congress-2018.PA5289

Marcon A, Locatelli F, Keidel D, Beckmeyer-Borowko A.B, Cerveri I, Dharmage S.C, Fuertes E, Garcia-Aymerich J, Heinrich J, Imboden M, Janson C, Johannessen A, Leynaert B, Pascual Erquicia S, Pesce G, Schaffner E, Svanes C, Urrutia I, Jarvis D, Probst-Hensch N.M, Accordini S, Ageing Lungs in European Cohorts study. Airway responsiveness to methacholine and incidence of COPD: an international prospective cohort study. Thorax. 2018;73(9):825-832. DOI: 10.1136/thoraxjnl-2017-211289

Vonk J.M, Nieuwenhuis M.A.E, Dijk F.N, Boudier A, Siroux V, Bouzigon E, Probst-Hensch N, Imboden M, Keidel D, Sin D, Bossé Y, Hao K, van den Berge M, Faiz A, Koppelman G.H, Postma D.S. Novel genes and insights in complete asthma remission: a genome-wide association study on clinical and complete asthma remission. Clin Exp Allergy. 2018;48(10):1286-1296. DOI: 10.1111/cea.13181

Guerra S, Carsin A.E, Keidel D, Sunyer J, Leynaert B, Janson C, Jarvis D, Stolz D, Rothe T, Pons M, Turk A, Anto J.M, Probst-Hensch N. Health-related quality of life and risk factors associated with spirometric restriction. Eur Respir J. 2017;49(5):1602096. DOI: 10.1183/13993003.02096-2016

Hansen S, Probst-Hensch N, Bettschart R, Pons M, Leynaert B, Gomez Real F, Rochat T, Dratva J, Schneider C, Keidel D, Schindler C, Zemp E. Early menarche and new onset of asthma: results from the SAPALDIA cohort study. Maturitas. 2017;101:57-63. DOI: 10.1016/j.maturitas.2017.04.012

Temam S, Burte E, Adam M, Antó J.M, Basagana X, Bousquet J, Carsin A.E, Galobardes B, Keidel D, Künzli N, Le Moual N, Sanchez M, Sunyer J, Bono R, Brunekreef B, Heinrich J, de Hoogh K, Jarvis D, Marcon A, Modig L, Nadif R, Nieuwenhuijsen M, Pin I, Siroux V, Stempfelet M, Tsai M, Probst-Hensch N. Socioeconomic position and outdoor nitrogen dioxide NO2 exposure in Western Europe: a multi-city analysis. Environ Int. 2017;101:117-124. DOI: 10.1016/j.envint.2016.12.026

Aguilera I, Dratva J, Caviezel S, Burdet L, de Groot E, Ducret-Stich R.E, Eeftens M, Keidel D, Meier R, Perez L, Rothe T, Schaffner E, Schmit-Trucksass A, Tsai M.Y, Schindler C, Künzli N, Probst-Hensch N. Particulate matter and subclinical atherosclerosis: associations between different particle sizes and sources with carotid intima-media thickness in the SAPALDIA study. Environ Health Perspect. 2016;124(11):1700-1706. DOI: 10.1289/EHP161

Curjuric I, Imboden M, Bridevaux P.O, Gerbase M.W, Haun M, Keidel D, Kumar A, Pons M, Rochat T, Schikowski T, Schindler C, von Eckardstein A, Kronenberg F, Probst-Hensch N.M. Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline. Age (Dordr). 2016;38(3):52. DOI: 10.1007/s11357-016-9917-y

Eeftens M, Meier R, Schindler C, Aguilera I, Phuleria H, Ineichen A, Davey M, Ducret-Stich R, Keidel D, Probst-Hensch N, Künzli N, Tsai M.Y. Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of particulate matter pollution in the Swiss SAPALDIA regions. Environ Health. 2016;15:53. DOI: 10.1186/s12940-016-0137-9

Adam M, Schikowski T, Carsin A.E, Cai Y, Jacquemin B, Sanchez M, Vierkötter A, Marcon A, Keidel D, Sugiri D, Al Kanani Z, Nadif R, Siroux V, Hardy R, Kuh D, Rochat T, Bridevaux P.O, Eeftens M, Tsai M.Y, Villani S, Phuleria H.C, Birk M, Cyrys J, Cirach M, de Nazelle A, Nieuwenhuijsen M.J, Forsberg B, de Hoogh K, Declerq C, Bono R, Piccioni P, Quass U, Heinrich J, Jarvis D, Pin I, Beelen R, Hoek G, Brunekreef B, Schindler C, Sunyer J, Kramer U, Kauffmann F, Hansell A.L, Künzli N, Probst-Hensch N. Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis. Eur Respir J. 2015;45(1):38-50. DOI: 10.1183/09031936.00130014

Bridevaux P.O, Dupuis-Lozeron E, Schindler C, Keidel D, Gerbase M.W, Probst-Hensch N.M, Bettschart R, Burdet L, Pons M, Rothe T, Turk A, Stolz D, Tschopp J.M, Künzli N, Rochat T. Spirometer replacement and serial lung function measurements in population studies: results from the SAPALDIA study. Am J Epidemiol. 2015;181(10):752-761. DOI: 10.1093/aje/kwu352

Eeftens M, Phuleria H, Meier R, Aguilera I, Corradi E, Davey M, Ducret-Stich R, Fierz M, Gehrig R, Ineichen A, Keidel D, Probst-Hensch N, Ragettli M, Schindler C, Künzli N, Tsai M.Y. Spatial and temporal variability of ultrafine particles, NO2, PM2.5, PM2.5 absorbance, PM10 and PMcoarse in Swiss study areas. Atmos Environ. 2015;111:60-70. DOI: 10.1016/j.atmosenv.2015.03.031

Guerra S, Halonen M, Vasquez M.M, Spangenberg A, Stern D.A, Morgan W.J, Wright A.L, Lavi I, Tarès L, Carsin A.E, Dobano C, Barreiro E, Zock J.P, Martínez-Moratalla J, Urrutia I, Sunyer J, Keidel D, Imboden M, Probst-Hensch N, Hallberg J, Melén E, Wickman M, Bousquet J, Belgrave D.C.M. Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study. Lancet Respir Med. 2015;3(8):613-620. DOI: 10.1016/S2213-2600(15)00196-4

Hansen S, Probst-Hensch N, Keidel D, Dratva J, Bettschart R, Pons M, Burdet L, Bridevaux P.O, Schikowski T, Schindler C, Rochat T, Zemp E. Gender differences in adult-onset asthma: results from the Swiss SAPALDIA cohort study. Eur Respir J. 2015;46(4):1011-1020. DOI: 10.1183/13993003.02278-2014

Jacquemin B, Siroux V, Sanchez M, Carsin A.E, Schikowski T, Adam M, Bellisario V, Buschka A, Bono R, Brunekreef B, Cai Y, Cirach M, Clavel-Chapelon F, Declercq C, de Marco R, de Nazelle A, Ducret-Stich R.E, Ferretti V.V, Gerbase M.W, Hardy R, Heinrich J, Janson C, Jarvis D, Al Kanaani Z, Keidel D, Kuh D, Le Moual N, Nieuwenhuijsen M.J, Marcon A, Modig L, Pin I, Rochat T, Schindler C, Sugiri D, Stempfelet M, Temam S, Tsai M.Y, Varraso R, Vienneau D, Vierkötter A, Hansell A.L, Kramer U, Probst-Hensch N.M, Sunyer J, Künzli N, Kauffmann F. Ambient air pollution and adult asthma incidence in six European cohorts (ESCAPE). Environ Health Perspect. 2015;123(6):613-621. DOI: 10.1289/ehp.1408206

Cai Y, Schikowski T, Adam M, Buschka A, Carsin A.E, Jacquemin B, Marcon A, Sanchez M, Vierkötter A, Al-Kanaani Z, Beelen R, Birk M, Brunekreef B, Cirach M, Clavel-Chapelon F, Declercq C, de Hoogh K, de Nazelle A, Ducret-Stich R.E, Ferretti V, Forsberg B, Gerbase M.W, Hardy R, Heinrich J, Hoek G, Jarvis D, Keidel D, Kuh D, Nieuwenhuijsen M.J, Ragettli M.S, Ranzi A, Rochat T, Schindler C, Sugiri D, Temam S, Tsai M.Y, Varraso R, Kauffmann F, Kramer U, Sunyer J, Künzli N, Probst-Hensch N, Hansell A.L. Cross-sectional associations between air pollution and chronic bronchitis: an ESCAPE meta-analysis across five cohorts. Thorax. 2014;69(11):1005-1014. DOI: 10.1136/thoraxjnl-2013-204352

Mehta A.J, Thun G.A, Imboden M, Ferrarotti I, Keidel D, Künzli N, Kromhout H, Miedinger D, Phuleria H, Rochat T, Russi E.W, Schindler C, Schwartz J, Vermeulen R, Luisetti M, Probst-Hensch N. Interactions between SERPINA1 PiMZ genotype, occupational exposure and lung function decline. Occup Environ Med. 2014;71(4):234-240. DOI: 10.1136/oemed-2013-101592