Publications

Mariner-Llicer C, Goig G.A, Torres-Puente M, Vashakidze S, Villamayor L.M, Saavedra-Cervera B, Mambuque E, Khurtsilava I, Avaliani Z, Rosenthal A, Gabrielian A, Shurgaia M, Shubladze N, García-Basteiro A.L, López M.G, Comas I. Genetic diversity within diagnostic sputum samples is mirrored in the culture of Mycobacterium tuberculosis across different settings. Nat Commun. 2024;15(1):7114. DOI: 10.1038/s41467-024-51266-0

Windels E.M, Wampande E.M, Joloba M.L, Boom W.H, Goig G.A, Cox H, Hella J, Borrell S, Gagneux S, Brites D, Stadler T. HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa. PLoS Pathog. 2024;20(5):e1011675. DOI: 10.1371/journal.ppat.1011675

Goig G.A, Menardo F, Salaam-Dreyer Z, Dippenaar A, Streicher E.M, Daniels J, Reuter A, Borrell S, Reinhard M, Dötsch A, Beisel C, Warren R.M, Cox H, Gagneux S. Effect of compensatory evolution in the emergence and transmission of rifampicin-resistant Mycobacterium tuberculosis in Cape Town, South Africa: a genomic epidemiology study. Lancet Microbe. 2023;4(7):e506-e515. DOI: 10.1016/S2666-5247(23)00110-6

Loiseau C, Windels E.M, Gygli S.M, Jugheli L, Maghradze N, Brites D, Ross A, Goig G, Reinhard M, Borrell S, Trauner A, Dötsch A, Aspindzelashvili R, Denes R, Reither K, Beisel C, Tukvadze N, Avaliani Z, Stadler T, Gagneux S. The relative transmission fitness of multidrug-resistant Mycobacterium tuberculosis in a drug resistance hotspot. Nat Commun. 2023;14:1988. DOI: 10.1038/s41467-023-37719-y

Walter K.S, Cohen T, Mathema B, Colijn C, Sobkowiak B, Comas I, Goig G.A, Croda J, Andrews J.R. Signatures of transmission in within-host M. tuberculosis variation. medRxiv. 2023(in press). DOI: 10.1101/2023.12.28.23300451

Cox H, Goig G.A, Salaam-Dreyer Z, Dippenaar A, Reuter A, Mohr-Holland E, Daniels J, Cudahy P.G.T, Nicol M.P, Borrell S, Reinhard M, Dötsch A, Beisel C, Gagneux S, Warren R.M, Furin J. Whole genome sequencing has the potential to improve treatment for rifampicin-resistant tuberculosis in high burden settings: a retrospective cohort study. J Clin Microbiol. 2022;60(3):e0236221. DOI: 10.1128/jcm.02362-21

Van Rie A, Walker T, de Jong B, Rupasinghe P, Riviere E, Dartois V, Sonnenkalb L, Machado D, Gagneux S, Supply P, Dreyer V, Niemann S, Goig G, Meehan C, Tagliani E, Cirillo D.M. Balancing access to BPaLM regimens and risk of resistance. Lancet Infect Dis. 2022;S1473-3099(22):00543-6. DOI: 10.1016/S1473-3099(22)00543-6

Cox H, Salaam-Dreyer Z, Goig G.A, Nicol M.P, Menardo F, Dippenaar A, Mohr-Holland E, Daniels J, Cudahy P.G.T, Borrell S, Reinhard M, Dötsch A, Beisel C, Reuter A, Furin J, Gagneux S, Warren R.M. Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis drug resistance in South Africa: a retrospective molecular epidemiology study. Lancet Microbe. 2021;2(11):e584-e593. DOI: 10.1016/S2666-5247(21)00144-0

López M.G, Chiner-Oms A, García de Viedma D, Ruiz-Rodriguez P, Bracho M.A, Cancino-Muñoz I, D'Auria G, de Marco G, García-González N, Goig G.A, Gómez-Navarro I, Jiménez-Serrano S, Martinez-Priego L, Ruiz-Hueso P, Ruiz-Roldán L, Torres-Puente M, Alberola J, Albert E, Aranzamendi Zaldumbide M, Bea-Escudero M.P, Boga J.A, Bordoy A.E, Canut-Blasco A, Carvajal A, Cilla Eguiluz G, Cordón Rodríguez M.L, Costa-Alcalde J.J, de Toro M, de Toro Peinado I, Del Pozo J.L, Duchêne S, Fernández-Pinero J, Fuster Escrivá B, Gimeno Cardona C, González Galán V, Gonzalo Jiménez N, Hernáez Crespo S, Herranz M, Lepe J.A, López-Causapé C, López-Hontangas J.L, Martín V, Martró E, Milagro Beamonte A, Montes Ros M, Moreno-Muñoz R, Navarro D, Navarro-Marí J.M, Not A, Oliver A, Palop-Borrás B, Parra Grande M, Pedrosa-Corral I, Pérez González M.C, Pérez-Lago L, Pérez-Ruiz M, Pineiro Vazquez L, Rabella N, Rezusta A, Robles Fonseca L, Rodríguez-Villodres A, Sanbonmatsu-Gámez S, Sicilia J, Soriano A, Tirado Balaguer M.D, Torres I, Tristancho A, Marimón J.M, SeqCOVID-Spain Consortium, Coscolla M, González-Candelas F, Comas I. The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant. Nat Genet. 2021;53(10):1405-1414. DOI: 10.1038/s41588-021-00936-6

Mariner-Llicer C, Goig G.A, Zaragoza-Infante L, Torres-Puente M, Villamayor L, Navarro D, Borras R, Chiner-Oms A, Comas I. Accuracy of an amplicon-sequencing nanopore approach to identify variants in tuberculosis drug-resistance-associated genes. Microb Genom. 2021;7(12):00074. DOI: 10.1099/mgen.0.000740