Publications

Alchalabi L, Schaffner E, Imboden M, Difloe-Geisert J.C, Zitzmann N.U, Probst-Hensch N. Removable dental prostheses and difficulties with chewing among frail individuals: results from the Swiss SAPALDIA cohort. Swiss Dent J. 2024;134(2):53-71. DOI: 10.61872/sdj-2024-02-04

Probst-Hensch N, Imboden M, Jeong A, Keidel D, Vermes T, Witzig M, Cullati S, Tancredi S, Noor N, Rodondi P.Y, Harju E, Michel G, Frank I, Kahlert C, Cusini A, Rodondi N, Chocano-Bedoya P.O, Bardoczi J.B, Stuber M.J, Vollrath F, Fehr J, Frei A, Kaufmann M, Geigges M, von Wyl V, Puhan M.A, Albanese E, Crivelli L, Lovison G.F, Corona Immunitas Research Group. Long-term trajectories of densely reported depressive symptoms during an extended period of the COVID-19 pandemic in Switzerland: social worries matter. Compr Psychiatry. 2024;130:152457. DOI: 10.1016/j.comppsych.2024.152457

Shrine N, Guyatt A.L, Erzurumluoglu A.M, Jackson V.E, Hobbs B.D, Melbourne C.A, Batini C, Fawcett K.A, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve N.F, Obeidat M, Zhao J.H, Wielscher M, Weiss S, Kentistou K.A, Cook J.P, Sun B.B, Zhou J, Hui J, Karrasch S, Imboden M, Harris S.E, Marten J, Enroth S, Kerr S.M, Surakka I, Vitart V, Lehtimäki T, Allen R.J, Bakke P.S, Beaty T.H, Bleecker E.R, Bossé Y, Brandsma C.A, Chen Z, Crapo J.D, Danesh J, DeMeo D.L, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell A.L, Hao K, Hoffman J.D, Hokanson J.E, Homuth G, Joshi P.K, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville J.C, Murray A, Nickle D.C, Packer R, Parker M.M, Paynton M.L, Porteous D.J, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin D.D, Smith B.H, Artigas M.S, Sparrow D, Tal-Singer R, Timmers Prhj, Van den Berge M, Whittaker J.C, Woodruff P.G, Yerges-Armstrong L.M, Troyanskaya O.G, Raitakari O.T, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary I.J, Probst-Hensch N.M, Schulz H, James A.L, Wilson J.F, Stubbe B, Zeggini E, Jarvelin M.R, Wareham N, Silverman E.K, Hayward C, Morris A.P, Butterworth A.S, Scott R.A, Walters R.G, Meyers D.A, Cho M.H, Strachan D.P, Hall I.P, Tobin M.D, Wain L.V. Author correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet. 2024;56(5):1032-1033. DOI: 10.1038/s41588-024-01752-4

Tancredi S, van der Linden B.W.A, Chiolero A, Cullati S, Imboden M, Probst-Hensch N, Keidel D, Witzig M, Dratva J, Michel G, Harju E, Frank I, Lorthe E, Baysson H, Stringhini S, Kahlert C.R, Bardoczi J.B, Haller M.L, Chocano-Bedoya P.O, Rodondi N, Amati R, Albanese E, Corna L, Crivelli L, Kaufmann M, Frei A, von Wyl V. Socioeconomic status and adherence to preventive measures during the COVID-19 pandemic in Switzerland: a population based digital cohort analysis. Int J Public Health. 2024;69:1606861. DOI: 10.3389/ijph.2024.1606861

Zhai J, Voraphani N, Imboden M, Keidel D, Liu C, Stern D.A, Venker C, Petersen H, Bosco A, Sherrill D.L, Morgan W.J, Tesfaigzi Y, Probst-Hensch N.M, Martinez F.D, Halonen M, Guerra S. Circulating biomarkers of airflow limitation across the life span. J Allergy Clin Immunol. 2024;153(6):1692-1703. DOI: 10.1016/j.jaci.2023.12.026

Budu-Aggrey A, Kilanowski A, Sobczyk M.K, Shringarpure S.S, Mitchell R, Reis K, Reigo A, Mägi R, Nelis M, Tanaka N, Brumpton B.M, Thomas L.F, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar J.V.T, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett K.A, Baurecht H, Rodriguez E, Alves A.C, Kumar A, Sleiman P.M, Chang X, Medina-Gomez C, Hu C, Xu C.J, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang C.A, Thiering E, Wu B, Kress S, Kothalawala D.M, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Njølstad P, Andreassen O.A, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson P.K.E, Szwajda A, Burchard E.G, Thyssen J.P, Hansen T, Kårhus L.L, Dantoft T.M, Jeanrenaud Acsn, Ghauri A, Arnold A, Homuth G, Lau S, Nöthen M.M, Hübner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma D.I, Hottenga J.J, Müller-Nurasyid M, Ahluwalia T.S, Stokholm J, Chawes B, Schoos A.M, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani L.A, Metspalu A, Terao C, Abuabara K, Løset M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan D.P, Grarup N, Linneberg A, Lee Y.A, Probst-Hensch N, Weidinger S, Jarvelin M.R, Melén E, Hakonarson H, Irvine A.D, Jarvis D, Nijsten T, Duijts L, Vonk J.M, Koppelmann G.H, Godfrey K.M, Barton S.J, Feenstra B, Pennell C.E, Sly P.D, Holt P.G, Williams L.K, Bisgaard H, Bønnelykke K, Curtin J, Simpson A, Murray C, Schikowski T, Bunyavanich S, Weiss S.T, Holloway J.W, Min J.L, Brown S.J, Standl M, Paternoster L. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nat Commun. 2023;14:6172. DOI: 10.1038/s41467-023-41180-2

Daniore P, Moser A, Höglinger M, Probst-Hensch N, Imboden M, Vermes T, Keidel D, Bochud M, Ortega Herrero N, Baggio S, Chocano-Bedoya P, Rodondi N, Tancredi S, Wagner C, Cullati S, Stringhini S, Gonseth Nusslé S, Veys-Takeuchi C, Zuppinger C, Harju E, Michel G, Frank I, Kahlert C.R, Albanese E, Crivelli L, Levati S, Amati R, Kaufmann M, Geigges M, Ballouz T, Frei A, Fehr J, von Wyl V. Interplay of digital proximity app use and SARS-CoV-2 vaccine uptake in Switzerland: analysis of two population-based cohort studies. Int J Public Health. 2023;68:1605812. DOI: 10.3389/ijph.2023.1605812

Govarts E, Gilles L, Rodriguez Martin L, Santonen T, Apel P, Alvito P, Anastasi E, Andersen H.R, Andersson A.M, Andryskova L, Antignac J.P, Appenzeller B, Barbone F, Barnett-Itzhaki Z, Barouki R, Berman T, Bil W, Borges T, Buekers J, Cañas-Portilla A, Covaci A, Csako Z, Den Hond E, Dvorakova D, Fabelova L, Fletcher T, Frederiksen H, Gabriel C, Ganzleben C, Göen T, Halldorsson T.I, Haug L.S, Horvat M, Huuskonen P, Imboden M, Jagodic Hudobivnik M, Janasik B, Janev Holcer N, Karakitsios S, Katsonouri A, Klanova J, Kokaraki V, Kold Jensen T, Koponen J, Laeremans M, Laguzzi F, Lange R, Lemke N, Lignell S, Lindroos A.K, Lobo Vicente J, Luijten M, Makris K.C, Mazej D, Melymuk L, Meslin M, Mol H, Montazeri P, Murawski A, Namorado S, Niemann L, Nubler S, Nunes B, Olafsdottir K, Palkovicova Murinova L, Papaioannou N, Pedraza-Diaz S, Piler P, Plichta V, Poteser M, Probst-Hensch N, Rambaud L, Rauscher-Gabernig E, Rausova K, Remy S, Riou M, Rosolen V, Rousselle C, Ruther M, Sarigiannis D, Silva M.J, Šlejkovec Z, Snoj Tratnik J, Stajnko A, Szigeti T, Tarazona J.V, Thomsen C, Tkalec Z, Tolonen H, Trnovec T, Uhl M, Van Nieuwenhuyse A, Vasco E, Verheyen V.J, Viegas S, Vinggaard A.M, Vogel N, Vorkamp K, Wasowicz W, Weber T, Wimmerova S, Woutersen M, Zimmermann P, Zvonar M, Koch H, Kolossa-Gehring M, Esteban López M, Castaño A, Stewart L, Sepai O, Schoeters G. Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014-2021). Int J Hyg Environ Health. 2023;249:114119. DOI: 10.1016/j.ijheh.2023.114119

Guyatt A, John C, Williams A.T, Shrine N, Reeve N.F, SpiroMeta Consortium, Sayers I, Hall I, Wain L.V, Sheehan N, Dudbridge F, Tobin M.D. Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease. Thorax. 2023;78(5):496-503. DOI: 10.1136/thoraxjnl-2021-217993

Harju E, Speierer A, Jungo K.T, Levati S, Baggio S, Tancredi S, Noor N, Rodondi P.Y, Cullati S, Imboden M, Keidel D, Witzig M, Frank I, Kohler P, Kahlert C, Crivelli L, Amati R, Albanese E, Kaufmann M, Frei A, Von Wyl V, Puhan M.A, Probst-Hensch N, Michel G, Rodondi N, Chocano-Bedoya P, Corona Immunitas Res Grp. Changes in healthcare utilization during the COVID-19 pandemic and potential causes : a cohort study from Switzerland. Int J Public Health. 2023;68:1606010. DOI: 10.3389/ijph.2023.1606010

Oosterwegel M.J, Ibi D, Portengen L, Probst-Hensch N, Tarallo S, Naccarati A, Imboden M, Jeong A, Robinot N, Scalbert A, Amaral A.F.S, van Nunen E, Gulliver J, Chadeau-Hyam M, Vineis P, Vermeulen R, Keski-Rahkonen P, Vlaanderen J. Variability of the human serum metabolome over 3 months in the EXPOsOMICS Personal Exposure Monitoring study. Environ Sci Technol. 2023;57(34):12752-12759. DOI: 10.1021/acs.est.3c03233

Ottenbros I.B, Ammann P, Imboden M, Fuhrimann S, Zock J.P, Lebret E, Vermeulen R.C.H, Nijssen R, Lommen A, Mol H, Vlaanderen J.J, Probst-Hensch N. Urinary pesticide mixture patterns and exposure determinants in the adult population from the Netherlands and Switzerland: application of a suspect screening approach. Environ Res. 2023;239(Pt 1):117216. DOI: 10.1016/j.envres.2023.117216

Probst-Hensch N, Jeong A, Keidel D, Imboden M, Lovison G. Depression trajectories during the COVID-19 pandemic in the high-quality health care setting of Switzerland: the COVCO-Basel cohort. Public Health. 2023;217:65-73. DOI: 10.1016/j.puhe.2023.01.010

Rodriguez Martin L, Gilles L, Helte E, Åkesson A, Tägt J, Covaci A, Sakhi A.K, Van Nieuwenhuyse A, Katsonouri A, Andersson A.M, Gutleb A.C, Janasik B, Appenzeller B, Gabriel C, Thomsen C, Mazej D, Sarigiannis D, Anastasi E, Barbone F, Tolonen H, Frederiksen H, Klanova J, Koponen J, Tratnik J.S, Pack K, Gudrun K, Ólafsdóttir K, Knudsen L.E, Rambaud L, Strumylaite L, Murinova L.P, Fabelova L, Riou M, Berglund M, Szabados M, Imboden M, Laeremans M, Eštóková M, Janev Holcer N, Probst-Hensch N, Vodrazkova N, Vogel N, Piler P, Schmidt P, Lange R, Namorado S, Kozepesy S, Szigeti T, Halldorsson T.I, Weber T, Jensen T.K, Rosolen V, Puklova V, Wasowicz W, Sepai O, Stewart L, Kolossa-Gehring M, Esteban-López M, Castaño A, Bessems J, Schoeters G, Govarts E. Time patterns in internal human exposure data to bisphenols, phthalates, DINCH, organophosphate flame retardants, cadmium and polyaromatic hydrocarbons in Europe. Toxics. 2023;11(10):819. DOI: 10.3390/toxics11100819

Sabatini S, Kaufmann M, Fadda M, Tancredi S, Noor N, Van Der Linden B.W.A, Cullati S, Frank I, Michel G, Harju E, Luedi C, Frei A, Ballouz T, Menges D, Fehr J, Kohler P, Kahlert C.R, Scheu V, Ortega N, Chocano-Bedoya P, Rodondi N, Stringhini S, Baysson H, Lorthe E, Zufferey M.C, Suggs L.S, Albanese E, Vincentini J, Bochud M, D'Acremont V, Nusslé S.G, Imboden M, Keidel D, Witzig M, Probst-Hensch N, von Wyl V. Factors associated with COVID-19 non-vaccination in Switzerland: a nationwide study. Int J Public Health. 2023;68:1605852. DOI: 10.3389/ijph.2023.1605852

Shrine N, Izquierdo A.G, Chen J, Packer R, Hall R.J, Guyatt A.L, Batini C, Thompson R.J, Pavuluri C, Malik V, Hobbs B.D, Moll M, Kim W, Tal-Singer R, Bakke P, Fawcett K.A, John C, Coley K, Piga N.N, Pozarickij A, Lin K, Millwood I.Y, Chen Z, Li L, China Kadoorie Biobank Collaborative Group, Wijnant S.R.A, Lahousse L, Brusselle G, Uitterlinden A.G, Manichaikul A, Oelsner E.C, Rich S.S, Barr R.G, Kerr S.M, Vitart V, Brown M.R, Wielscher M, Imboden M, Jeong A, Bartz T.M, Gharib S.A, Flexeder C, Karrasch S, Gieger C, Peters A, Stubbe B, Hu X, Ortega V.E, Meyers D.A, Bleecker E.R, Gabriel S.B, Gupta N, Smith A.V, Luan J, Zhao J.H, Hansen A.F, Langhammer A, Willer C, Bhatta L, Porteous D, Smith B.H, Campbell A, Sofer T, Lee J, Daviglus M.L, Yu B, Lim E, Xu H, O'Connor G.T, Thareja G, Albagha O.M.E, Qatar Genome Program Research (QGPR) Consortium, Suhre K, Granell R, Faquih T.O, Hiemstra P.S, Slats A.M, Mullin B.H, Hui J, James A, Beilby J, Patasova K, Hysi P, Koskela J.T, Wyss A.B, Jin J, Sikdar S, Lee M, May-Wilson S, Pirastu N, Kentistou K.A, Joshi P.K, Timmers Prhj, Williams A.T, Free R.C, Wang X, Morrison J.L, Gilliland F.D, Chen Z, Wang C.A, Foong R.E, Harris S.E, Taylor A, Redmond P, Cook J.P, Mahajan A, Lind L, Palviainen T, Lehtimäki T, Raitakari O.T, Kaprio J, Rantanen T, Pietiläinen K.H, Cox S.R, Pennell C.E, Hall G.L, Gauderman W.J, Brightling C, Wilson J.F, Vasankari T, Laitinen T, Salomaa V, Mook-Kanamori D.O, Timpson N.J, Zeggini E, Dupuis J, Hayward C, Brumpton B, Langenberg C, Weiss S, Homuth G, Schmidt C.O, Probst-Hensch N, Jarvelin M.R, Morrison A.C, Polasek O, Rudan I, Lee J.H, Sayers I, Rawlins E.L, Dudbridge F, Silverman E.K, Strachan D.P, Walters R.G, Morris A.P, London S.J, Cho M.H, Wain L.V, Hall I.P, Tobin M.D. Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nat Genet. 2023;55(3):410-422. DOI: 10.1038/s41588-023-01314-0

Shrine N, Izquierdo A.G, Chen J, Packer R, Hall R.J, Guyatt A.L, Batini C, Thompson R.J, Pavuluri C, Malik V, Hobbs B.D, Moll M, Kim W, Tal-Singer R, Bakke P, Fawcett K.A, John C, Coley K, Piga N.N, Pozarickij A, Lin K, Millwood I.Y, Chen Z, Li L, Wijnant S.R.A, Lahousse L, Brusselle G, Uitterlinden A.G, Manichaikul A, Oelsner E.C, Rich S.S, Barr R.G, Kerr S.M, Vitart V, Brown M.R, Wielscher M, Imboden M, Jeong A, Bartz T.M, Gharib S.A, Flexeder C, Karrasch S, Gieger C, Peters A, Stubbe B, Hu X, Ortega V.E, Meyers D.A, Bleecker E.R, Gabriel S.B, Gupta N, Smith A.V, Luan J, Zhao J.H, Hansen A.F, Langhammer A, Willer C, Bhatta L, Porteous D, Smith B.H, Campbell A, Sofer T, Lee J, Daviglus M.L, Yu B, Lim E, Xu H, O'Connor G.T, Thareja G, Albagha O.M.E, Suhre K, Granell R, Faquih T.O, Hiemstra P.S, Slats A.M, Mullin B.H, Hui J, James A, Beilby J, Patasova K, Hysi P, Koskela J.T, Wyss A.B, Jin J, Sikdar S, Lee M, May-Wilson S, Pirastu N, Kentistou K.A, Joshi P.K, Timmers Prhj, Williams A.T, Free R.C, Wang X, Morrison J.L, Gilliland F.D, Chen Z, Wang C.A, Foong R.E, Harris S.E, Taylor A, Redmond P, Cook J.P, Mahajan A, Lind L, Palviainen T, Lehtimäki T, Raitakari O.T, Kaprio J, Rantanen T, Pietiläinen K.H, Cox S.R, Pennell C.E, Hall G.L, Gauderman W.J, Brightling C, Wilson J.F, Vasankari T, Laitinen T, Salomaa V, Mook-Kanamori D.O, Timpson N.J, Zeggini E, Dupuis J, Hayward C, Brumpton B, Langenberg C, Weiss S, Homuth G, Schmidt C.O, Probst-Hensch N, Jarvelin M.R, Morrison A.C, Polasek O, Rudan I, Lee J.H, Sayers I, Rawlins E.L, Dudbridge F, Silverman E.K, Strachan D.P, Walters R.G, Morris A.P, London S.J, Cho M.H, Wain L.V, Hall I.P, Tobin M.D. Author correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nat Genet. 2023;55(10):1778-1779. DOI: 10.1038/s41588-023-01531-7

Tancredi S, Chiolero A, Wagner C, Haller M.L, Chocano-Bedoya P, Ortega N, Rodondi N, Kaufmann L, Lorthe E, Baysson H, Stringhini S, Michel G, Ludi C, Harju E, Frank I, Imboden M, Witzig M, Keidel D, Probst-Hensch N, Amati R, Albanese E, Corna L, Crivelli L, Vincentini J, Gonseth Nussle S, Bochud M, D'Acremont V, Kohler P, Kahlert C.R, Cusini A, Frei A, Puhan M.A, Geigges M, Kaufmann M, Fehr J, Cullati S, Corona Immunitas Research Group. Seroprevalence trends of anti-SARS-CoV-2 antibodies and associated risk factors: a population-based study. Infection. 2023;51(5):1453-1465. DOI: 10.1007/s15010-023-02011-0

Tancredi S, Ulyte A, Wagner C, Keidel D, Witzig M, Imboden M, Probst-Hensch N, Amati R, Albanese E, Levati S, Crivelli L, Kohler P, Cusini A, Kahlert C, Harju E, Michel G, Ludi C, Ortega N, Baggio S, Chocano-Bedoya P, Rodondi N, Ballouz T, Frei A, Kaufmann M, Von Wyl V, Lorthe E, Baysson H, Stringhini S, Schneider V, Kaufmann L, Wieber F, Volken T, Zysset A, Dratva J, Cullati S, Corona Immunitas Research Group. Changes in socioeconomic resources and mental health after the second COVID-19 wave (2020-2021): a longitudinal study in Switzerland. Int J Equity Health. 2023;22:51. DOI: 10.1186/s12939-023-01853-2

Jeong A, Eze I.C, Vienneau D, de Hoogh K, Keidel D, Rothe T, Burdet L, Holloway J.W, Jarvis D, Kronenberg F, Lovison G, Imboden M, Probst-Hensch N. Residential greenness-related DNA methylation changes. Environ Int. 2022;158:106945. DOI: 10.1016/j.envint.2021.106945

Jeong A, Galliker F, Imboden M, Keidel D, de Hoogh K, Vienneau D, Siegrist M, Crivelli L, Lovison G, Probst-Hensch N. Residential exposure to greenspace and life satisfaction in times of COVID-19: a cross-sectional analysis of 9444 participants from a population-based study in Basel-Stadt and Basel-Landschaft. Swiss Med Wkly. 2022;152:w30204. DOI: 10.4414/smw.2022.w30204

Obas K.A, Kwiatkowski M, Schaffner E, Lang U.E, Stolz D, Eze I.C, Imboden M, Probst-Hensch N. Depression and cardiovascular disease are not linked by high blood pressure: findings from the SAPALDIA cohort. Sci Rep. 2022;12:5516. DOI: 10.1038/s41598-022-09396-2

Sanchez D, Jeong A, Essé C, Bassa F.K, Koné S, Acka F, Laubhouet-Koffi V, Kouassi D, Utzinger J, N'Goran E.K, Bonfoh B, Imboden M, Holloway J.W, Eze I.C. Validity and cardio-metabolic risk profiles of DNA methylation clocks among adults in south-central Côte d’Ivoire. Epigenetics Commun. 2022;2:1. DOI: 10.1186/s43682-022-00008-8

Speierer A, Chocano-Bedoya P.O, Anker D, Schmid A, Keidel D, Vermes T, Imboden M, Levati S, Franscella G, Corna L, Amati R, Harju E, Luedi C, Michel G, Veys-Takeuchi C, Zuppinger C, Nussle S.G, D'Acremont V, Tall I, Salberg E, Baysson H, Lorthe E, Pennacchio F, Frei A, Kaufmann M, Geigges M, West E.A, Schwab N, Cullati S, Chiolero A, Kahlert C, Stringhini S, Vollrath F, Probst-Hensch N, Rodondi N, Puhan M.A, von Wyl V. The Corona Immunitas Digital Follow-Up eCohort to monitor impacts of the SARS-CoV-2 pandemic in Switzerland: study protocol and first results. Int J Public Health. 2022;67:1604506. DOI: 10.3389/ijph.2022.1604506

Thériault S, Imboden M, Biggs M.L, Austin T.R, Aeschbacher S, Schaffner E, Brody J.A, Bartz T.M, Risch M, Grossmann K, Lin H.J, Soliman E.Z, Post W.S, Risch L, Krieger J.E, Pereira A.C, Heckbert S.R, Sotoodehnia N, Probst-Hensch N.M, Conen D. Genome-wide analyses identify SCN5A as a susceptibility locus for premature atrial contraction frequency. iScience. 2022;25(10):105210. DOI: 10.1016/j.isci.2022.105210

Cerletti P, Eze I.C, Keidel D, Schaffner E, Stolz D, Gasche-Soccal P.M, Rothe T, Imboden M, Probst-Hensch N. Perceived built environment, health-related quality of life and health care utilization. PLoS One. 2021;16(5):e0251251. DOI: 10.1371/journal.pone.0251251

Keidel D, Vermes T, Witzig M, Jeong A, Galliker F, Tertemiz E, Schaffner E, de Hoogh K, Pärli K, Lovison G, Imboden M, Probst-Hensch N. COVCO-Basel - Corona Immunitas: Wissenschaftlicher Schlussbericht - Juli 2020 bis August 2021. Basel: Swiss Tropical and Public Health Institute, 2021

McCartney D.L, Min J.L, Richmond R.C, Lu A.T, Sobczyk M.K, Davies G, Broer L, Guo X, Jeong A, Jung J, Kasela S, Katrinli S, Kuo P.L, Matias-Garcia P.R, Mishra P.P, Nygaard M, Palviainen T, Patki A, Raffield L.M, Ratliff S.M, Richardson T.G, Robinson O, Soerensen M, Sun D, Tsai P.C, van der Zee M.D, Walker R.M, Wang X, Wang Y, Xia R, Xu Z, Yao J, Zhao W, Correa A, Boerwinkle E, Dugue P.A, Durda P, Elliott H.R, Gieger C, Genetics of DNA Methylation Consortium, de Geus E.J.C, Harris S.E, Hemani G, Imboden M, Kahonen M, Kardia S.L.R, Kresovich J.K, Li S, Lunetta K.L, Mangino M, Mason D, McIntosh A.M, Mengel-From J, Moore A.Z, Murabito J.M, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Ollikainen M, Pankow J.S, Pedersen N.L, Peters A, Polidoro S, Porteous D.J, Raitakari O, Rich S.S, Sandler D.P, Sillanpaa E, Smith A.K, Southey M.C, Strauch K, Tiwari H, Tanaka T, Tillin T, Uitterlinden A.G, Van Den Berg D.J, van Dongen J, Wilson J.G, Wright J, Yet I, Arnett D, Bandinelli S, Bell J.T, Binder A.M, Boomsma D.I, Chen W, Christensen K, Conneely K.N, Elliott P, Ferrucci L, Fornage M, Hagg S, Hayward C, Irvin M, Kaprio J, Lawlor D.A, Lehtimaki T, Lohoff F.W, Milani L, Milne R.L, Probst-Hensch N, Reiner A.P, Ritz B, Rotter J.I, Smith J.A, Taylor J.A, van Meurs J.B.J, Vineis P, Waldenberger M, Deary I.J, Relton C.L, Horvath S, Marioni R.E. Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Genome Biol. 2021;22:194. (TOPMed). DOI: 10.1186/s13059-021-02398-9

Probst-Hensch N, Jeong A, Stolz D, Pons M, Soccal P.M, Bettschart R, Jarvis D, Holloway J.W, Kronenberg F, Imboden M, Schindler C, Lovison G.F. Causal effects of body mass index on airflow obstruction and forced mid-expiratory flow: a Mendelian randomization study taking interactions and age-specific instruments into consideration toward a life course perspective. Front Public Health. 2021;9:584955. DOI: 10.3389/fpubh.2021.584955

van Nunen E, Hoek G, Tsai M.Y, Probst-Hensch N, Imboden M, Jeong A, Naccarati A, Tarallo S, Raffaele D, Nieuwenhuijsen M, Vlaanderen J, Gulliver J, Amaral A.F.S, Vineis P, Vermeulen R. Short-term personal and outdoor exposure to ultrafine and fine particulate air pollution in association with blood pressure and lung function in healthy adults. Environ Res. 2021;194:110579. DOI: 10.1016/j.envres.2020.110579

Accordini S, Calciano L, Marcon A, Pesce G, Anto J.M, Beckmeyer-Borowko A.B, Carsin A.E, Corsico A.G, Imboden M, Janson C, Keidel D, Locatelli F, Svanes C, Burney P.G.J, Jarvis D, Probst-Hensch N.M, Minelli C. Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study. Sci Rep. 2020;10:3452. DOI: 10.1038/s41598-020-60478-5

Aebi N.J, Bringolf-Isler B, Schaffner E, Caviezel S, Imboden M, Probst-Hensch N. Patterns of cross-sectional and predictive physical activity in Swiss adults aged 52+: results from the SAPALDIA cohort. Swiss Med Wkly. 2020;150:w20266. DOI: 10.4414/smw.2020.20266

Amaral A.F.S, Imboden M, Wielscher M, Rezwan F.I, Minelli C, Garcia-Aymerich J, Peralta G.P, Auvinen J, Jeong A, Schaffner E, Beckmeyer-Borowko A, Holloway J.W, Jarvelin M.R, Probst-Hensch N.M, Jarvis D.L, ALEC consortium. Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study. BMC Pulm Med. 2020;20:171. DOI: 10.1186/s12890-020-01212-9

Carsin A.E, Keidel D, Fuertes E, Imboden M, Weyler J, Nowak D, Heinrich J, Pascual Erquicia S, Martinez-Moratalla J, Huerta I, Sanchez J.L, Schaffner E, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Leynaert B, Cerveri I, Squillacioti G, Accordini S, Gislason T, Svanes C, Toren K, Forsberg B, Janson C, Jogi R, Emtner M, Gomez Real F, Jarvis D, Guerra S, Dharmage S.C, Probst-Hensch N, Garcia-Aymerich J. Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of two population-based cohorts. Am J Epidemiol. 2020;89(12):1521-1528. DOI: 10.1093/aje/kwaa087

Cerletti P, Eze I.C, Schaffner E, Foraster M, Vienneau D, Cajochen C, Wunderli J.M, Röösli M, Stolz D, Pons M, Imboden M, Probst-Hensch N. The independent association of source-specific transportation noise exposure, noise annoyance and noise sensitivity with health-related quality of life. Environ Int. 2020;143:105960. DOI: 10.1016/j.envint.2020.105960

Cerletti P, Keidel D, Imboden M, Schindler C, Probst-Hensch N. The modifying role of physical activity in the cross-sectional and longitudinal association of health-related quality of life with physiological functioning-based latent classes and metabolic syndrome. Health Qual Life Outcomes. 2020;18:345. DOI: 10.1186/s12955-020-01557-z

Demetz E, Tymoszuk P, Hilbe R, Volani C, Haschka D, Heim C, Auer K, Lener D, Zeiger L.B, Pfeifhofer-Obermair C, Boehm A, Obermair G.J, Ablinger C, Coassin S, Lamina C, Kager J, Petzer V, Asshoff M, Schroll A, Nairz M, Dichtl S, Seifert M, von Raffay L, Fischer C, Barros-Pinkelnig M, Brigo N, Valente de Souza L, Sopper S, Hirsch J, Graber M, Gollmann-Tepekoylu C, Holfeld J, Halper J, Macheiner S, Gostner J, Vogel G.F, Pechlaner R, Moser P, Imboden M, Marques-Vidal P, Probst-Hensch N.M, Meiselbach H, Strauch K, Peters A, Paulweber B, Willeit J, Kiechl S, Kronenberg F, Theurl I, Tancevski I, Weiss G. The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development. Eur Heart J. 2020;41(40):3949-3959. DOI: 10.1093/eurheartj/ehaa140

Eze I.C, Foraster M, Schaffner E, Vienneau D, Pieren R, Imboden M, Wunderli J.M, Cajochen C, Brink M, Röösli M, Probst-Hensch N. Incidence of depression in relation to transportation noise exposure and noise annoyance in the SAPALDIA study. Environ Int. 2020;144:106014. DOI: 10.1016/j.envint.2020.106014

Eze I.C, Jeong A, Schaffner E, Rezwan F.I, Ghantous A, Foraster M, Vienneau D, Kronenberg F, Herceg Z, Vineis P, Brink M, Wunderli J.M, Schindler C, Cajochen C, Röösli M, Holloway J.W, Imboden M, Probst-Hensch N. Genome-wide DNA methylation in peripheral blood and long-term exposure to source-specific transportation noise and air pollution: the SAPALDIA study. Environ Health Perspect. 2020;128(6):67003. DOI: 10.1289/EHP6174

Fawcett K.A, Obeidat M, Melbourne C, Shrine N, Guyatt A.L, John C, Luan J, Richmond A, Moksnes M.R, Granell R, Weiss S, Imboden M, May-Wilson S, Hysi P, Boutin T.S, Portas L, Flexeder C, Harris S.E, Wang C.A, Lyytikainen L.P, Palviainen T, Foong R.E, Keidel D, Minelli C, Langenberg C, Bosse Y, Van den Berge M, Sin D.D, Hao K, Campbell A, Porteous D, Padmanabhan S, Smith B.H, Evans D.M, Ring S, Langhammer A, Hveem K, Willer C, Ewert R, Stubbe B, Pirastu N, Klaric L, Joshi P.K, Patasova K, Massimo M, Polasek O, Starr J.M, Karrasch S, Strauch K, Meitinger T, Rudan I, Rantanen T, Pietilainen K, Kahonen M, Raitakari O.T, Hall G.L, Sly P.D, Pennell C.E, Kaprio J, Lehtimaki T, Vitart V, Deary I.J, Jarvis D, Wilson J.F, Spector T, Probst-Hensch N, Wareham N.J, Volzke H, Henderson J, Strachan D.P, Brumpton B.M, Hayward C, Hall I.P, Tobin M.D, Wain L.V. Variants associated with HHIP expression have sex-differential effects on lung function. Wellcome Open Res. 2020;5:111. DOI: 10.12688/wellcomeopenres.15846.1

Hoang T.T, Sikdar S, Xu C.J, Lee M.K, Cardwell J, Forno E, Imboden M, Jeong A, Madore A.M, Qi C, Wang T, Bennett B.D, Ward J.M, Parks C.G, Beane-Freeman L.E, King D, Motsinger-Reif A, Umbach D.M, Wyss A.B, Schwartz D.A, Celedon J.C, Laprise C, Ober C, Probst-Hensch N, Yang I.V, Koppelman G.H, London S.J. Epigenome-wide association study of DNA methylation and adult asthma in the agricultural lung health study. Eur Respir J. 2020;56(3):2000217. DOI: 10.1183/13993003.00217-2020

Mancini F.R, Laine J.E, Tarallo S, Vlaanderen J, Vermeulen R, van Nunen E, Hoek G, Probst-Hensch N, Imboden M, Jeong A, Gulliver J, Chadeau-Hyam M, Nieuwenhuijsen M, de Kok T.M, Piepers J, Krauskopf J, Kleinjans J.C.S, Vineis P, Naccarati A. microRNA expression profiles and personal monitoring of exposure to particulate matter. Environ Pollut. 2020;263(Pt B):114392. DOI: 10.1016/j.envpol.2020.114392

Rezwan F.I, Imboden M, Amaral A.F.S, Wielscher M, Jeong A, Triebner K, Real F.G, Jarvelin M.R, Jarvis D, Probst-Hensch N.M, Holloway J.W. Association of adult lung function with accelerated biological aging. Aging. 2020;12(1):518-542. DOI: 10.18632/aging.102639

Schmidt J.C, Vogt S, Imboden M, Schaffner E, Grize L, Zemp E, Probst-Hensch N, Zitzmann N.U. Dental and periodontal health in a Swiss population-based sample of older adults: a cross-sectional study. Eur J Oral Sci. 2020;128:508-517. DOI: 10.1111/eos.12738

van Nunen E, Vermeulen R, Tsai M.Y, Probst-Hensch N, Ineichen A, Imboden M, Naccarati A, Tarallo S, Raffaele D, Ranzi A, Nieuwenhuijsen M, Jarvis D, Amaral A.F, Vlaanderen J, Meliefste K, Brunekreef B, Vineis P, Gulliver J, Hoek G. Associations between modeled residential outdoor and measured personal exposure to ultrafine particles in four European study areas. Atmos Environ. 2020;226:117353. DOI: 10.1016/j.atmosenv.2020.117353

West E.A, Anker D, Amati R, Richard A, Wisniak A, Butty A, Albanese E, Bochud M, Chiolero A, Crivelli L, Cullati S, d'Acremont V, Epure A.M, Fehr J, Flahault A, Fornerod L, Frank I, Frei A, Michel G, Gonseth S, Guessous I, Imboden M, Kahlert C.R, Kaufmann L, Kohler P, Mösli N, Paris D, Probst-Hensch N, Rodondi N, Stringhini S, Vermes T, Vollrath F, Puhan M.A, Corona Immunitas Research Group. Corona immunitas: study protocol of a nationwide program of SARS-CoV-2 seroprevalence and seroepidemiologic studies in Switzerland. Int J Public Health. 2020;65:1529–1548. DOI: 10.1007/s00038-020-01494-0

Carsin A.E, Fuertes E, Schaffner E, Jarvis D, Antó J.M, Heinrich J, Bellisario V, Svanes C, Keidel D, Imboden M, Weyler J, Nowak D, Martinez-Moratalla J, Gullón J.A, Sanchez Ramos J.L, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Cerveri I, Accordini S, Gislason T, Toren K, Forsberg B, Janson C, Jogi R, Emtner M, Gómez Real F, Raza W, Leynaert B, Pascual S, Guerra S, Dharmage S.C, Probst-Hensch N, Garcia-Aymerich J. Restrictive spirometry pattern is associated with low physical activity levels. A population based international study. Respir Med. 2019;146:116-123. DOI: 10.1016/j.rmed.2018.11.017

Eze I.C, Essé C, Bassa F.K, Koné S, Acka F, Schindler C, Imboden M, Laubhouet-Koffi V, Kouassi D, N'Goran E.K, Utzinger J, Bonfoh B, Probst-Hensch N. Asymptomatic Plasmodium infection and glycemic control in adults: results from a population-based survey in south-central Côte d'Ivoire. Diabetes Res Clin Pract. 2019;156:107845. DOI: 10.1016/j.diabres.2019.107845

Imboden M, Wielscher M, Rezwan F.I, Amaral A.F.S, Schaffner E, Jeong A, Beckmeyer-Borowko A, Harris S.E, Starr J.M, Deary I.J, Flexeder C, Waldenberger M, Peters A, Schulz H, Chen S, Sunny S.K, Karmaus W.J.J, Jiang Y, Erhart G, Kronenberg F, Arathimos R, Sharp G.C, Henderson A.J, Fu Y, Piirilä P, Pietiläinen K.H, Ollikainen M, Johansson A, Gyllensten U, de Vries M, van der Plaat D.A, de Jong K, Boezen H.M, Hall I.P, Tobin M.D, Jarvelin M.R, Holloway J.W, Jarvis D, Probst-Hensch N.M. Epigenome-wide association study of lung function level and its change. Eur Respir J. 2019;54:1900457. DOI: 10.1183/13993003.00457-2019

Jeong A, Imboden M, Ghantous A, Novoloaca A, Carsin A.E, Kogevinas M, Schindler C, Lovison G, Herceg Z, Cuenin C, Vermeulen R, Jarvis D, Amaral A.F.S, Kronenberg F, Vineis P, Probst-Hensch N. DNA methylation in inflammatory pathways modifies the association between BMI and adult-onset non-atopic asthma. Int J Environ Res Public Health. 2019;16(4):600. DOI: 10.3390/ijerph16040600

Meier-Girard D, Delgado-Eckert E, Schaffner E, Schindler C, Künzli N, Adam M, Pichot V, Kronenberg F, Imboden M, Frey U, Probst-Hensch N. Association of long-term exposure to traffic-related PM10 with heart rate variability and heart rate dynamics in healthy subjects. Environ Int. 2019;125:107-116. DOI: 10.1016/j.envint.2019.01.031

Mostafavi N, Jeong A, Vlaanderen J, Imboden M, Vineis P, Jarvis D, Kogevinas M, Probst-Hensch N, Vermeulen R. The mediating effect of immune markers on the association between ambient air pollution and adult-onset asthma. Sci Rep. 2019;9:8818. DOI: 10.1038/s41598-019-45327-4

Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve N.F, Guyatt A.L, Jackson V.E, Shrine N, Qiao D, Bartz T.M, Kim D.K, Lee M.K, Latourelle J.C, Li X, Morrow J.D, Obeidat M, Wyss A.B, Bakke P, Barr R.G, Beaty T.H, Belinsky S.A, Brusselle G.G, Crapo J.D, de Jong K, DeMeo D.L, Fingerlin T.E, Gharib S.A, Gulsvik A, Hall I.P, Hokanson J.E, Kim W.J, Lomas D.A, London S.J, Meyers D.A, O'Connor G.T, Rennard S.I, Schwartz D.A, Sliwinski P, Sparrow D, Strachan D.P, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk J.M, Yim J.J, Zhou X, Bosse Y, Manichaikul A, Lahousse L, Silverman E.K, Boezen H.M, Wain L.V, Tobin M.D, Hobbs B.D, Cho M.H, SpiroMeta Consortium, International COPD Genetics Consortium. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nat Genet. 2019;51(3):494-505. DOI: 10.1038/s41588-018-0342-2

Shrine N, Guyatt A.L, Erzurumluoglu A.M, Jackson V.E, Hobbs B.D, Melbourne C.A, Batini C, Fawcett K.A, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve N.F, Obeidat M, Zhao J.H, Wielscher M, Understanding Society Scientific Group, Weiss S, Kentistou K.A, Cook J.P, Sun B.B, Zhou J, Hui J, Karrasch S, Imboden M, Harris S.E, Marten J, Enroth S, Kerr S.M, Surakka I, Vitart V, Lehtimaki T, Allen R.J, Bakke P.S, Beaty T.H, Bleecker E.R, Bosse Y, Brandsma C.A, Chen Z, Crapo J.D, Danesh J, DeMeo D.L, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell A.L, Hao K, Hoffman J.D, Hokanson J.E, Homuth G, Joshi P.K, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville J.C, Murray A, Nickle D.C, Packer R, Parker M.M, Paynton M.L, Porteous D.J, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin D.D, Smith B.H, Artigas M.S, Sparrow D, Tal-Singer R, Timmers Prhj, Van den Berge M, Whittaker J.C, Woodruff P.G, Yerges-Armstrong L.M, Troyanskaya O.G, Raitakari O.T, Kahonen M, Polasek O, Gyllensten U, Rudan I, Deary I.J, Probst-Hensch N.M, Schulz H, James A.L, Wilson J.F, Stubbe B, Zeggini E, Jarvelin M.R, Wareham N, Silverman E.K, Hayward C, Morris A.P, Butterworth A.S, Scott R.A, Walters R.G, Meyers D.A, Cho M.H, Strachan D.P, Hall I.P, Tobin M.D, Wain L.V. Author correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet. 2019;51:1067-1068. DOI: 10.1038/s41588-019-0438-3

Shrine N, Guyatt A.L, Erzurumluoglu A.M, Jackson V.E, Hobbs B.D, Melbourne C.A, Batini C, Fawcett K.A, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve N.F, Obeidat M, Zhao J.H, Wielscher M, Understanding Society Scientific Group, Weiss S, Kentistou K.A, Cook J.P, Sun B.B, Zhou J, Hui J, Karrasch S, Imboden M, Harris S.E, Marten J, Enroth S, Kerr S.M, Surakka I, Vitart V, Lehtimäki T, Allen R.J, Bakke P.S, Beaty T.H, Bleecker E.R, Bossé Y, Brandsma C.A, Chen Z, Crapo J.D, Danesh J, DeMeo D.L, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell A.L, Hao K, Hoffman J.D, Hokanson J.E, Homuth G, Joshi P.K, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville J.C, Murray A, Nickle D.C, Packer R, Parker M.M, Paynton M.L, Porteous D.J, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin D.D, Smith B.H, Soler Artigas M, Sparrow D, Tal-Singer R, Timmers Prhj, Van den Berge M, Whittaker J.C, Woodruff P.G, Yerges-Armstrong L.M, Troyanskaya O.G, Raitakari O.T, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary I.J, Probst-Hensch N.M, Schulz H, James A.L, Wilson J.F, Stubbe B, Zeggini E, Jarvelin M.R, Wareham N, Silverman E.K, Hayward C, Morris A.P, Butterworth A.S, Scott R.A, Walters R.G, Meyers D.A, Cho M.H, Strachan D.P, Hall I.P, Tobin M.D, Wain L.V. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet. 2019;51(3):481-493. DOI: 10.1038/s41588-018-0321-7

Accordini S, Calciano L, Marcon A, Pesce G, Anto J, Beckmeyer-Borowko A, Corsico A, Imboden M, Janson C, Keidel D, Locatelli F, Svanes C, Jarvis D, Probst-Hensch N, Minelli C. Incidence of airflow obstruction over 20 years in Europe. Eur Respir J, 2018;52(Suppl. 62):PA2267. DOI: 10.1183/13993003.congress-2018.PA2267

Amaral A.F.S, Imboden M, Wielscher M, Rezwan F.I, Minelli C, Garcia-Aymerich J, Peralta G.P, Auvinen J, Jeong A, Schaffner E, Beckmeyer-Borowko A, Holloway J.W, Jarvelin M.R, Probst-Hensch N, Jarvis D.L. Body mass index and lung function: a two-step epigenetic Mendelian randomization study. Eur Respir J, 2018;52(Suppl. 62):PA1276. DOI: 10.1183/13993003.congress-2018.PA1276

Beckmeyer-Borowko A, Imboden M, Rezwan F.I, Wielscher M, Amaral A.F.S, Jeong A, Schaffner E, Auvinen J, Sebert S, Karhunen V, Bettschart R, Turk A, Pons M, Stolz D, Kronenberg F, Arathimos R, Sharp G.C, Relton C, Henderson A.J, Jarvelin M.R, Jarvis D, Holloway J.W, Probst-Hensch N.M. SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts. Respir Res. 2018;19(1):156. DOI: 10.1186/s12931-018-0850-8

Carsin A.E, Keidel D, Fuertes E, Imboden M, Weyler J, Nowak D, Heinrich J, Urrutia I, Martinez-Moratalla J, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Leynaert B, Cerveri I, Bono R, Accordini S, Amaral A, Gislason T, Svanes C, Toren K, Forsberg B, Janson C, Dharmage S, Jogi R, Anto J, Probst-Hensch N, Garcia-Aymerich J. Physical activity and incidence of restrictive spirometry pattern in adults. Eur Respir J, 2018;52(Suppl. 62):PA5289. DOI: 10.1183/13993003.congress-2018.PA5289

Curjuric I, Imboden M, Bettschart R, Caviezel S, Dratva J, Pons M, Rothe T, Schmidt-Trucksäss A, Stolz D, Thun G.A, Eckardstein A.V, Kronenberg F, Ferrarotti I, Probst-Hensch N.M. Alpha-1 antitrypsin deficiency: from the lung to the heart?. Atherosclerosis. 2018;270:166-172. DOI: 10.1016/j.atherosclerosis.2018.01.042

Demenais F, Margaritte-Jeannin P, Barnes K.C, Cookson W.O.C, Altmuller J, Ang W, Barr R.G, Beaty T.H, Becker A.B, Beilby J, Bisgaard H, Bjornsdottir U.S, Bleecker E, Bonnelykke K, Boomsma D.I, Bouzigon E, Brightling C.E, Brossard M, Brusselle G.G, Burchard E, Burkart K.M, Bush A, Chan-Yeung M, Chung K.F, Couto Alves A, Curtin J.A, Custovic A, Daley D, de Jongste J.C, Del-Rio-Navarro B.E, Donohue K.M, Duijts L, Eng C, Eriksson J.G, Farrall M, Fedorova Y, Feenstra B, Ferreira M.A, Freidin M.B, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib S.A, Gilliland F, Granell R, Graves P.E, Gudbjartsson D.F, Haahtela T, Heckbert S.R, Heederik D, Heinrich J, Heliovaara M, Henderson J, Himes B.E, Hirose H, Hirschhorn J.N, Hofman A, Holt P, Hottenga J, Hudson T.J, Hui J, Imboden M, Ivanov V, Jaddoe V.W.V, James A, Janson C, Jarvelin M.R, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kahonen M, Kantor D.B, Karunas A.S, Khusnutdinova E, Koppelman G.H, Kozyrskyj A.L, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee Y.A, Lehtimaki T, Letort S, Levin A.M, Li G, Liang L, Loehr L.R, London S.J, Loth D.W, Manichaikul A, Marenholz I, Martinez F.J, Matheson M.C, Mathias R.A, Matsumoto K, Mbarek H, McArdle W.L, Melbye M, Melen E, Meyers D, Michel S, Mohamdi H, Musk A.W, Myers R.A, Nieuwenhuis M.A.E, Noguchi E, O'Connor G.T, Ogorodova L.M, Palmer C.D, Palotie A, Park J.E, Pennell C.E, Pershagen G, Polonikov A, Postma D.S, Probst-Hensch N, Puzyrev V.P, Raby B.A, Raitakari O.T, Ramasamy A, Rich S.S, Robertson C.F, Romieu I, Salam M.T, Salomaa V, Schlunssen V, Scott R, Selivanova P.A, Sigsgaard T, Simpson A, Siroux V, Smith L.J, Solodilova M, Standl M, Stefansson K, Strachan D.P, Stricker B.H, Takahashi A, Thompson P.J, Thorleifsson G, Thorsteinsdottir U, Tiesler C.M.T, Torgerson D.G, Tsunoda T, Uitterlinden A.G, Van der Valk R.J.P, Vaysse A, Vedantam S, Von Berg A, Von Mutius E, Vonk J.M, Waage J, Wareham N.J, Weiss S.T, White W.B, Wickman M, Widen E, Willemsen G, Williams L.K, Wouters I.M, Yang J.J, Zhao J.H, Moffatt M.F, Ober C, Nicolae D.L, Australian Asthma Genetics Consortium Collaborators. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 2018;50:42-53. (AAGC). DOI: 10.1038/s41588-017-0014-7

Gulliver J, Morley D, Dunster C, McCrea A, Van Nunen E, Tsai M, Probst-Hensch N, Eeftens M, Imboden M, Ducret-Stich R, Naccarati A, Cirachi M, Vermeulen, Vineis P, Hoek G, Kelly F.J. Land use regression models for the oxidative potential of fine particles (PM2.5) in five European areas. Environ Res. 2018;160:247-255. DOI: 10.1016/j.envres.2017.10.002

Htun N.S.N, Odermatt P, Paboriboune P, Sayasone S, Vongsakid M, Phimolsarn-Nusith V, Tran X.D, Ounnavong P.S, Andriama-Hefasoa N, Senvanpan N.D, Homsana A, Lianosay B, Xayavong D, Robinson D.R, Bounsavath P, Prasayasith P.P, Syphan S.D, Lu Y.X, Thilakoun K, Xaiyaphet X.S, Vongngakesone P.T, Eze I.C, Imboden M, Sripa B, Reinharz D, Probst-Hensch N. Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic: a cross-sectional study. Infect Dis Poverty. 2018;7:105. DOI: 10.1186/s40249-018-0488-2

Jackson V.E, Latourelle J.C, Wain L.V, Smith A.V, Grove M.L, Bartz T.M, Obeidat M, Province M.A, Gao W, Qaiser B, Porteous D.J, Cassano P.A, Ahluwalia T.S, Grarup N, Li J, Altmaier E, Marten J, Harris S.E, Manichaikul A, Pottinger T.D, Li-Gao R, Lind-Thomsen A, Mahajan A, Lahousse L, Imboden M, Teumer A, Prins B, Lyytikainen L.P, Eiriksdottir G, Franceschini N, Sitlani C.M, Brody J.A, Bosse Y, Timens W, Kraja A, Loukola A, Tang W, Liu Y, Bork-Jensen J, Justesen J.M, Linneberg A, Lange L.A, Rawal R, Karrasch S, Huffman J.E, Smith B.H, Davies G, Burkart K.M, Mychaleckyj J.C, Bonten T.N, Enroth S, Lind L, Brusselle G.G, Kumar A, Stubbe B, Understanding Society Scientific Group, Kahonen M, Wyss A.B, Psaty B.M, Heckbert S.R, Hao K, Rantanen T, Kritchevsky S.B, Lohman K, Skaaby T, Pisinger C, Hansen T, Schulz H, Polasek O, Campbell A, Starr J.M, Rich S.S, Mook-Kanamori D.O, Johansson A, Ingelsson E, Uitterlinden A.G, Weiss S, Raitakari O.T, Gudnason V, North K.E, Gharib S.A, Sin D.D, Taylor K.D, O'Connor G.T, Kaprio J, Harris T.B, Pederson O, Vestergaard H, Wilson J.G, Strauch K, Hayward C, Kerr S, Deary I.J, Barr R.G, de Mutsert R, Gyllensten U, Morris A.P, Ikram M.A, Probst-Hensch N, Glaser S, Zeggini E, Lehtimaki T, Strachan D.P, Dupuis J, Morrison A.C, Hall I.P, Tobin M.D, London S.J. Meta-analysis of exome array data identifies six novel genetic loci for lung function. Wellcome Open Res. 2018;3:4. DOI: 10.12688/wellcomeopenres.12583.3

Jeong A, Fiorito G, Keski-Rahkonen P, Imboden M, Kiss A, Robinot N, Gmuender H, Vlaandere J, Vermeulen R, Kyrtopoulos S, Herceg Z, Ghantous A, Lovison G, Galassi C, Ranzi A, Krogh V, Grioni S, Agnoli C, Sacerdote C, Mostafavi N, Naccarati A, Scalbert A, Vineis P, Probst-Hensch N, EXPOsOMICS Consortium. Perturbation of metabolic pathways mediates the association of air pollutants with asthma and cardiovascular diseases. Environ Int. 2018;119:334-345. DOI: 10.1016/j.envint.2018.06.025

Marcon A, Locatelli F, Keidel D, Beckmeyer-Borowko A.B, Cerveri I, Dharmage S.C, Fuertes E, Garcia-Aymerich J, Heinrich J, Imboden M, Janson C, Johannessen A, Leynaert B, Pascual Erquicia S, Pesce G, Schaffner E, Svanes C, Urrutia I, Jarvis D, Probst-Hensch N.M, Accordini S, Ageing Lungs in European Cohorts study. Airway responsiveness to methacholine and incidence of COPD: an international prospective cohort study. Thorax. 2018;73(9):825-832. DOI: 10.1136/thoraxjnl-2017-211289

Mostafavi N, Vermeulen R, Ghantous A, Hoek G, Probst-Hensch N, Herceg Z, Tarallo S, Naccarati A, Kleinjans J.C.S, Imboden M, Jeong A, Morley D, Amaral A.F.S, Van Nunen E, Gulliver J, Chadeau-Hyam M, Vineis P, Vlaanderen J. Acute changes in DNA methylation in relation to 24 h personal air pollution exposure measurements: a panel study in four European countries. Environ Int. 2018;120:11-21. DOI: 10.1016/j.envint.2018.07.026

Vonk J.M, Nieuwenhuis M.A.E, Dijk F.N, Boudier A, Siroux V, Bouzigon E, Probst-Hensch N, Imboden M, Keidel D, Sin D, Bossé Y, Hao K, van den Berge M, Faiz A, Koppelman G.H, Postma D.S. Novel genes and insights in complete asthma remission: a genome-wide association study on clinical and complete asthma remission. Clin Exp Allergy. 2018;48(10):1286-1296. DOI: 10.1111/cea.13181

Waage J, Standl M, Curtin J.A, Jessen L.E, Thorsen J, Tian C, Schoettler N, Me Research Team, AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia T.S, Alves A.C, Amaral A.F.S, Anto J.M, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt C.E.M, Bleecker E.R, Bonas-Guarch S, Boomsma D.I, Brix S, Bunyavanich S, Burchard E.G, Chen Z, Curjuric I, Custovic A, den Dekker H.T, Dharmage S.C, Dmitrieva J, Duijts L, Ege M.J, Gauderman W.J, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, Jaddoe V.W.V, Jarvelin M.R, Jarvis D.L, Jensen K.K, Jonsdottir I, Kabesch M, Kaprio J, Kumar A, Lee Y.A, Levin A.M, Li X, Lorenzo-Diaz F, Melen E, Mercader J.M, Meyers D.A, Myers R, Nicolae D.L, Nohr E.A, Palviainen T, Paternoster L, Pennell C.E, Pershagen G, Pino-Yanes M, Probst-Hensch N.M, Ruschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, Thompson P.J, Torrent M, Torrents D, Tung J.Y, Wang C.A, Weidinger S, Weiss S, Willemsen G, Williams L.K, Ober C, Hinds D.A, Ferreira M.A, Bisgaard H, Strachan D.P, Bonnelykke K. Author correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (Nature Genetics, (2018), 50, 8, (1072-1080), 10.1038/s41588-018-0157-1). Nat Genet. 2018;50(9):1343. DOI: 10.1038/s41588-018-0197-6

Adam M, Imboden M, Schaffner E, Boes E, Kronenberg F, Pons M, Bettschart R, Barthelemy J.C, Schindler C, Probst-Hensch N. The adverse impact of obesity on heart rate variability is modified by a NFE2L2 gene variant: the SAPALDIA Cohort. Int J Cardiol. 2017;228:341-346. DOI: 10.1016/j.ijcard.2016.11.049

De Jong K, Vonk J.M, Imboden M, Lahousse L, Hofman A, Brusselle G.G, Probst-Hensch N.M, Postma D.S, Boezen H.M. Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure. Respir Res. 2017;18:142. DOI: 10.1186/s12931-017-0625-7

Eze I.C, Esse C, Bassa F.K, Koné S, Acka F, Yao L, Imboden M, Jaeger F.N, Schindler C, Dosso M, Laubhouet-Koffi V, Kouassi D, N'Goran E.K, Utzinger J, Bonfoh B, Probst-Hensch N. Côte d'Ivoire Dual Burden of Disease (CoDuBu): study protocol to investigate the co-occurrence of chronic infections and noncommunicable diseases in rural settings of epidemiological transition. JMIR Res Protoc. 2017;6(10):e210. DOI: 10.2196/resprot.8599

Eze I.C, Foraster M, Schaffner E, Vienneau D, Héritier H, Rudzik F, Thiesse L, Pieren R, Imboden M, von Eckardstein A, Schindler C, Brink M, Cajochen C, Wunderli J.M, Röösli M, Probst-Hensch N. Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study. Int J Epidemiol. 2017;46(4):1115-1125. DOI: 10.1093/ije/dyx020

Eze I.C, Imboden M, Foraster M, Schaffner E, Kumar A, Vienneau D, Héritier H, Rudzik F, Thiesse L, Pieren R, von Eckardstein A, Schindler C, Brink M, Wunderli J.M, Cajochen C, Röösli M, Probst-Hensch N. Exposure to night-time traffic noise, melatonin-regulating gene variants and change in glycemia in adults. Int J Environ Res Public Health. 2017;14(12):E1492. DOI: 10.3390/ijerph14121492

Gorski M, van der Most P.J, Teumer A, Chu A.Y, Li M, Mijatovic V, Nolte I.M, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa M.F, Aspelund T, Attia J, Biffar R, Bochud M, Boerwinkle E, Borecki I, Bottinger E.P, Chen M.H, Chouraki V, Ciullo M, Coresh J, Cornelis M.C, Curhan G.C, Adamo A.P, Dehghan A, Dengler L, Ding J, Eiriksdottir G, Endlich K, Enroth S, Esko T, Franco O.H, Gasparini P, Gieger C, Girotto G, Gottesman O, Gudnason V, Gyllensten U, Hancock S.J, Harris T.B, Helmer C, Hollerer S, Hofer E, Hofman A, Holliday E.G, Homuth G, Hu F.B, Huth C, Hutri-Kahonen N, Hwang S.J, Imboden M, Johansson A, Kahonen M, Konig W, Kramer H, Kramer B.K, Kumar A, Kutalik Z, Lambert J.C, Launer L.J, Lehtimaki T, Borst M.H, Navis G, Swertz M, Liu Y, Lohman K, Loos R.J.F, Lu Y, Lyytikainen L.P, McEvoy M.A, Meisinger C, Meitinger T, Metspalu A, Metzger M, Mihailov E, Mitchell P, Nauck M, Oldehinkel A.J, Olden M, Wjh Penninx B, Pistis G, Pramstaller P.P, Probst-Hensch N, Raitakari O.T, Rettig R, Ridker P.M, Rivadeneira F, Robino A, Rosas S.E, Ruderfer D, Ruggiero D, Saba Y, Sala C, Schmidt H, Schmid R, Scott R.J, Sedaghat S, Smith A.V, Sorice R, Stengel B, Stracke S, Strauch K, Toniolo D, Uitterlinden A.G, Ulivi S, Viikari J.S, Volker U, Vollenweider P, Volzke H, Vuckovic D, Waldenberger M, Wang J.J, Yang Q, Chasman D.I, Tromp G, Snieder H, Heid I.M, Fox C.S, Kottgen A, Pattaro C, Boger C.A, Fuchsberger C. Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017;7:46835. DOI: 10.1038/srep46835

Gorski M, van der Most P.J, Teumer A, Chu A.Y, Li M, Mijatovic V, Nolte I.M, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa M.F, Aspelund T, Attia J, Biffar R, Bochud M, Boerwinkle E, Borecki I, Bottinger E.P, Chen M.H, Chouraki V, Ciullo M, Coresh J, Cornelis M.C, Curhan G.C, d'Adamo A.P, Dehghan A, Dengler L, Ding J, Eiriksdottir G, Endlich K, Enroth S, Esko T, Franco O.H, Gasparini P, Gieger C, Girotto G, Gottesman O, Gudnason V, Gyllensten U, Hancock S.J, Harris T.B, Helmer C, Hollerer S, Hofer E, Hofman A, Holliday E.G, Homuth G, Hu F.B, Huth C, Hutri-Kahonen N, Hwang S.J, Imboden M, Johansson A, Kahonen M, Konig W, Kramer H, Kramer B.K, Kumar A, Kutalik Z, Lambert J.C, Launer L.J, Lehtimaki T, de Borst M, Navis G, Swertz M, Liu Y, Lohman K, Loos R.J.F, Lu Y, Lyytikainen L.P, McEvoy M.A, Meisinger C, Meitinger T, Metspalu A, Metzger M, Mihailov E, Mitchell P, Nauck M, Oldehinkel A.J, Olden M, Wjh Penninx B, Pistis G, Pramstaller P.P, Probst-Hensch N, Raitakari O.T, Rettig R, Ridker P.M, Rivadeneira F, Robino A, Rosas S.E, Ruderfer D, Ruggiero D, Saba Y, Sala C, Schmidt H, Schmid R, Scott R.J, Sedaghat S, Smith A.V, Sorice R, Stengel B, Stracke S, Strauch K, Toniolo D, Uitterlinden A.G, Ulivi S, Viikari J.S, Volker U, Vollenweider P, Volzke H, Vuckovic D, Waldenberger M, Jin Wang J, Yang Q, Chasman D.I, Tromp G, Snieder H, Heid I.M, Fox C.S, Kottgen A, Pattaro C, Boger C.A, Fuchsberger C. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017;7:45040. DOI: 10.1038/srep45040

Jeong A, Imboden M, Hansen S, Zemp E, Bridevaux P.O, Lovison G, Schindler C, Probst-Hensch N. Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort. Respir Med. 2017;125:25-32. DOI: 10.1016/j.rmed.2017.02.014

Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman J.E, Tromp G, Fuchsberger C, Gorski M, Lyytikainen L.P, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, Ahluwalia T.S, Arking D.E, Bihlmeyer N.A, Boger C.A, Carroll R.J, Chasman D.I, Cornelis M.C, Dehghan A, Faul J.D, Feitosa M.F, Gambaro G, Gasparini P, Giulianini F, Heid I, Huang J, Imboden M, Jackson A.U, Jeff J, Jhun M.A, Katz R, Kifley A, Kilpelainen T.O, Kumar A, Laakso M, Li-Gao R, Lohman K, Lu Y, Magi R, Malerba G, Mihailov E, Mohlke K.L, Mook-Kanamori D.O, Robino A, Ruderfer D, Salvi E, Schick U.M, Schulz C.A, Smith A.V, Smith J.A, Traglia M, Yerges-Armstrong L.M, Zhao W, Goodarzi M.O, Kraja A.T, Liu C, Wessel J, Charge Glycemic-T2D Working Group, Charge Blood Pressure Working Group, Boerwinkle E, Borecki I.B, Bork-Jensen J, Bottinger E.P, Braga D, Brandslund I, Brody J.A, Campbell A, Carey D.J, Christensen C, Coresh J, Crook E, Curhan G.C, Cusi D, de Boer I.H, de Vries A.P, Denny J.C, Devuyst O, Dreisbach A.W, Endlich K, Esko T, Franco O.H, Fulop T, Gerhard G.S, Glumer C, Gottesman O, Grarup N, Gudnason V, Harris T.B, Hayward C, Hocking L, Hofman A, Hu F.B, Husemoen L.L, Jackson R.D, Jorgensen T, Jorgensen M.E, Kahonen M, Kardia S.L, Konig W, Kooperberg C, Kriebel J, Launer L.J, Lauritzen T, Lehtimaki T, Levy D, Linksted P, Linneberg A, Liu Y, Loos R.J, Lupo A, Meisinger C, Melander O, Metspalu A, Mitchell P, Nauck M, Nurnberg P, Orho-Melander M, Parsa A, Pedersen O, Peters A, Peters U, Polasek O, Porteous D, Probst-Hensch N.M, Psaty B.M, Qi L, Raitakari O.T, Reiner A.P, Rettig R, Ridker P.M, Rivadeneira F, Rossouw J.E, Schmidt F, Siscovick D, Soranzo N, Strauch K, Toniolo D, Turner S.T, Uitterlinden A.G, Ulivi S, Velayutham D, Volker U, Volzke H, Waldenberger M, Wang J.J, Weir D.R, Witte D, Kuivaniemi H, Fox C.S, Franceschini N, Goessling W, Kottgen A, Chu A.Y. SOS2 and ACP1 loci identified through large-scale exome chip analysis regulate kidney development and function. J Am Soc Nephrol. 2017;28(3):981-994. DOI: 10.1681/ASN.2016020131

Machin M, Amaral A.F, Wielscher M, Rezwan F.I, Imboden M, Jarvelin M.R, Adcock I.M, Probst-Hensch N, Holloway J.W, Jarvis D.L. Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies. BMC Pulm Med. 2017;17:54. DOI: 10.1186/s12890-017-0397-3

Rava M, Ahmed I, Kogevinas M, Le Moual N, Bouzigon E, Curjuric I, Dizier M.H, Dumas O, Gonzalez J.R, Imboden M, Mehta A.J, Tubert-Bitter P, Zock J.P, Jarvis D, Probst-Hensch N.M, Demenais F, Nadif R. Genes interacting with occupational exposures to low molecular weight agents and irritants on adult-onset asthma in three European studies. Environ Health Perspect. 2017;125(2):207-214. DOI: 10.1289/EHP376

van Nunen E, Vermeulen R, Tsai M.Y, Probst-Hensch N, Ineichen A, Davey M, Imboden M, Ducret-Stich R, Naccarati A, Raffaele D, Ranzi A, Ivaldi C, Galassi C, Nieuwenhuijsen M, Curto A, Donaire-Gonzalez D, Cirach M, Chatzi L, Kampouri M, Vlaanderen J, Meliefste K, Buijtenhuijs D, Brunekreef B, Morley D, Vineis P, Gulliver J, Hoek G. Land use regression models for ultrafine particles in six European areas. Environ Sci Technol. 2017;51(6):3336-3345. DOI: 10.1021/acs.est.6b05920

Vonk J.M, Scholtens S, Postma D.S, Moffatt M.F, Jarvis D, Ramasamy A, Wjst M, Omenaas E.R, Bouzigon E, Demenais F, Nadif R, Siroux V, Polonikov A.V, Solodilova M, Ivanov V.P, Curjuric I, Imboden M, Kumar A, Probst-Hensch N, Ogorodova L.M, Puzyrev V.P, Bragina E.Y, Freidin M.B, Nolte I.M, Farrall A.M, Cookson W.O, Strachan D.P, Koppelman G.H, Boezen H.M. Adult onset asthma and interaction between genes and active tobacco smoking: the GABRIEL consortium. PLoS One. 2017;12(3):e0172716. DOI: 10.1371/journal.pone.0172716

Wain L.V, Shrine N, Artigas M.S, Erzurumluoglu A.M, Noyvert B, Bossini-Castillo L, Obeidat M, Henry A.P, Portelli M.A, Hall R.J, Billington C.K, Rimington T.L, Fenech A.G, John C, Blake T, Jackson V.E, Allen R.J, Prins B.P, Understanding Society Scientific Group, Campbell A, Porteous D.J, Jarvelin M.R, Wielscher M, James A.L, Hui J, Wareham N.J, Zhao J.H, Wilson J.F, Joshi P.K, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch N.M, Karrasch S, Gieger C, Deary I.J, Harris S.E, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr S.M, Polasek O, Kahonen M, Surakka I, Vitart V, Hayward C, Lehtimaki T, Raitakari O.T, Evans D.M, Henderson A.J, Pennell C.E, Wang C.A, Sly P.D, Wan E.S, Busch R, Hobbs B.D, Litonjua A.A, Sparrow D.W, Gulsvik A, Bakke P.S, Crapo J.D, Beaty T.H, Hansel N.N, Mathias R.A, Ruczinski I, Barnes K.C, Bosse Y, Joubert P, van den Berge M, Brandsma C.A, Pare P.D, Sin D.D, Nickle D.C, Hao K, Gottesman O, Dewey F.E, Bruse S.E, Carey D.J, Kirchner H.L, Geisinger-Regeneron Discov EHR Collaboration, Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger E.P, Loos R.J, Walters R.G, Chen Z, Millwood I.Y, Vaucher J, Kurmi O.P, Li L, Hansell A.L, Brightling C, Zeggini E, Cho M.H, Silverman E.K, Sayers I, Trynka G, Morris A.P, Strachan D.P, Hall I.P, Tobin M.D. Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nat Genet. 2017;49(3):416-425. DOI: 10.1038/ng.3787

Walther D, Curjuric I, Dratva J, Schaffner E, Quinto C, Schmidt-Trucksäss A, Eze I.C, Burdet L, Pons M, Gerbase M, Imboden M, Schindler C, Probst-Hensch N. Hypertension, diabetes and lifestyle in the long-term - results from a Swiss population-based cohort. Prev Med. 2017;97:56-61. DOI: 10.1016/j.ypmed.2016.12.016

Abramson M.J, Schindler C, Schikowski T, Bircher A.J, Burdet L, Gerbase M.W, Imboden M, Rochat T, Schmid-Grendelmeier P, Turk A.J, Zemp E, Künzli N, Probst-Hensch N. Rhinitis in Swiss adults is associated with asthma and early life factors, but not second hand tobacco smoke or obesity. Allergol Int. 2016;65(2):192-198. DOI: 10.1016/j.alit.2015.11.004

Boillat-Blanco N, Bovet P, Ramaiya K.L, Mganga M, Minja L.T, Saleh L, Imboden M, Schindler C, Gagneux S, Daubenberger C, Reither K, Probst-Hensch N. Association between tuberculosis, diabetes and 25 hydroxyvitamin D in Tanzania: a longitudinal case control study. BMC Infect Dis. 2016;16:626. DOI: 10.1186/s12879-016-1960-x

Curjuric I, Imboden M, Bridevaux P.O, Gerbase M.W, Haun M, Keidel D, Kumar A, Pons M, Rochat T, Schikowski T, Schindler C, von Eckardstein A, Kronenberg F, Probst-Hensch N.M. Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline. Age (Dordr). 2016;38(3):52. DOI: 10.1007/s11357-016-9917-y

Eze I.C, Imboden M, Kumar A, Adam M, Von Eckardstein A, Stolz D, Gerbase M.W, Künzli N, Turk A, Schindler C, Kronenberg F, Probst-Hensch N. A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM10 exposure and diabetes. Environ Health. 2016;15:39. DOI: 10.1186/s12940-016-0120-5

Eze I.C, Imboden M, Kumar A, Von Eckardstein A, Stolz D, Gerbase M.W, Künzli N, Pons M, Kronenberg F, Schindler C, Probst-Hensch N. Air pollution and diabetes association: modification by type 2 diabetes genetic risk score. Environ Int. 2016;94:263-271. DOI: 10.1016/j.envint.2016.04.032

Pattaro C, Teumer A, Gorski M, Chu A.Y, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen M.H, Pers T.H, Johnson A.D, Ko Y.A, Fuchsberger C, Tayo B, Nalls M, Feitosa M.F, Isaacs A, Dehghan A, D'Adamo P, Adeyemo A, Dieffenbach A.K, Zonderman A.B, Nolte I.M, van der Most P.J, Wright A.F, Shuldiner A.R, Morrison A.C, Hofman A, Smith A.V, Dreisbach A.W, Franke A, Uitterlinden A.G, Metspalu A, Tonjes A, Lupo A, Robino A, Johansson A, Demirkan A, Kollerits B, Freedman B.I, Ponte B, Oostra B.A, Paulweber B, Kramer B.K, Mitchell B.D, Buckley B.M, Peralta C.A, Hayward C, Helmer C, Rotimi C.N, Shaffer C.M, Muller C, Sala C, van Duijn C.M, Saint-Pierre A, Ackermann D, Shriner D, Ruggiero D, Toniolo D, Lu Y, Cusi D, Czamara D, Ellinghaus D, Siscovick D.S, Ruderfer D, Gieger C, Grallert H, Rochtchina E, Atkinson E.J, Holliday E.G, Boerwinkle E, Salvi E, Bottinger E.P, Murgia F, Rivadeneira F, Ernst F, Kronenberg F, Hu F.B, Navis G.J, Curhan G.C, Ehret G.B, Homuth G, Coassin S, Thun G.A, Pistis G, Gambaro G, Malerba G, Montgomery G.W, Eiriksdottir G, Jacobs G, Li G, Wichmann H.E, Campbell H, Schmidt H, Wallaschofski H, Volzke H, Brenner H, Kroemer H.K, Kramer H, Lin H, Mateo Leach I, Ford I, Guessous I, Rudan I, Prokopenko I, Borecki I, Heid I.M, Kolcic I, Persico I, Jukema J.W, Wilson J.F, Felix J.F, Divers J, Lambert J.C, Stafford J.M, Gaspoz J.M, Smith J.A, Faul J.D, Wang J.J, Ding J, Hirschhorn J.N, Attia J, Whitfield J.B, Chalmers J, Viikari J, Coresh J, Denny J.C, Karjalainen J, Fernandes J.K, Endlich K, Butterbach K, Keene K.L, Lohman K, Portas L, Launer L.J, Lyytikainen L.P, Yengo L, Franke L, Ferrucci L, Rose L.M, Kedenko L, Rao M, Struchalin M, Kleber M.E, Cavalieri M, Haun M, Cornelis M.C, Ciullo M, Pirastu M, de Andrade M, McEvoy M.A, Woodward M, Adam M, Cocca M, Nauck M, Imboden M, Waldenberger M, Pruijm M, Metzger M, Stumvoll M, Evans M.K, Sale M.M, Kahonen M, Boban M, Bochud M, Rheinberger M, Verweij N, Bouatia-Naji N, Martin N.G, Hastie N, Probst-Hensch N, Soranzo N, Devuyst O, Raitakari O, Gottesman O, Franco O.H, Polasek O, Gasparini P, Munroe P.B, Ridker P.M, Mitchell P, Muntner P, Meisinger C, Smit J.H, Kovacs P, Wild P.S, Froguel P, Rettig R, Magi R, Biffar R, Schmid R, Middelberg R.P, Carroll R.J, Penninx B.W, Scott R.J, Katz R, Sedaghat S, Wild S.H, Kardia S.L, Ulivi S, Hwang S.J, Enroth S, Kloiber S, Trompet S, Stengel B, Hancock S.J, Turner S.T, Rosas S.E, Stracke S, Harris T.B, Zeller T, Zemunik T, Lehtimaki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Volker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen W.M, Igl W, Marz W, Koenig W, Lieb W, Loos R.J, Liu Y, Snieder H, Pramstaller P.P, Parsa A, O'Connell J.R, Susztak K, Hamet P, Tremblay J, de Boer I.H, Boger C.A, Goessling W, Chasman D.I, Kottgen A, Kao W.H, Fox C.S. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun. 2016;7:10023. DOI: 10.1038/ncomms10023

Sarnowski C, Sugier P.E, Granell R, Jarvis D, Dizier M.H, Ege M, Imboden M, Laprise C, Khusnutdinova E.K, Freidin M.B, Cookson W.O.C, Moffatt M, Lathop M, Siroux V, Ogorodova L.M, Karunas A.S, James A, Probst-Hensch N.M, von Erika M, Pin I, Kogevinas M, Henderson A.J, Demenais F, Bouzigon E. Identification of a new locus at 16q12 associated with time-to-asthma onset. J Allergy Clin Immunol. 2016;138(4):1071-1080. DOI: 10.1016/j.jaci.2016.03.018

Artigas M.S, Wain L.V, Miller S, Kheirallah A.K, Huffman J.E, Ntalla I, Shrine N, Obeidat M, Trochet H, McArdle W.L, Alves A.C, Hui J, Zhao J.H, Joshi P.K, Teumer A, Albrecht E, Imboden M, Rawal R, Lopez L.M, Marten J, Enroth S, Surakka I, Polasek O, Lyytikäinen L.P, Granell R, Hysi P.G, Flexeder C, Mahajan A, Beilby J, Bosse Y, Brandsma C.A, Campbell H, Gieger C, Glaser S, Gonzalez J.R, Grallert H, Hammond C.J, Harris S.E, Hartikainen A.L, Heliövaara M, Henderson J, Hocking L, Horikoshi M, Hutri-Kähönen N, Ingelsson E, Johansson A, Kemp J.P, Kolcic I, Kumar A, Lind L, Melen E, Musk A.W, Navarro P, Nickle D.C, Padmanabhan S, Raitakari O.T, Ried J.S, Ripatti S, Schulz H, Scott R.A, Sin D.D, Starr J.M, Vinuela A, Völzke H, Wild S.H, Wright A.F, Zemunik T, Jarvis D.L, Spector T.D, Evans D.M, Lehtimaki T, Vitart V, Kähönen M, Gyllensten U, Rudan I, Deary I.J, Karrasch S, Probst-Hensch N.M, Heinrich J, Stubbe B, Wilson J.F, Wareham N.J, James A.L, Morris A.P, Jarvelin M.R, Hayward C, Sayers I, Strachan D.P, Hall I.P, Tobin M.D. Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nat Commun. 2015;6:8658. DOI: 10.1038/ncomms9658

Eze I.C, Imboden M, Kumar A, Von Eckardstein A, Stolz D, Gerbase M.W, Künzli N, Rochat T, Kronenberg F, Schindler C, Probst-Hensch N. Modification of ambient air pollution and diabetes association by type 2 diabetes genetic risk score of 48 variants. Trop Med Int Health, 2015;20(Suppl. 1):127-128

Eze I.C, Schaffner E, Foraster M, Imboden M, Von Eckardstein A, Gerbase M.W, Rothe T, Rochat T, Künzli N, Schindler C, Probst-Hensch N. Long-term exposure to ambient air pollution and metabolic syndrome in adults. PLoS One. 2015;10(6):e0130337. DOI: 10.1371/journal.pone.0130337

Gharib S.A, Loth D.W, Soler Artigas M, Birkland T.P, Wilk J.B, Wain L.V, Brody J, Obeidat M, Hancock D.B, Tang W, Rawal R, Boezen H.M, Imboden M, Huffman J.E, Lahousse L, Alves A.C, Manichaikul A, Hui J, Morrison A.C, Ramasamy A, Smith A.V, Gudnason V, Surakka I, Vitart V, Evans D.M, Strachan D.P, Deary I.J, Hofman A, Glaser S, Wilson J.F, North K.E, Zhao J.H, Heckbert S.R, Jarvis D.L, Probst-Hensch N, Schulz H, Barr R.G, Jarvelin M.R, O'Connor G.T, Kähönen M, Cassano P.A, Hysi P.G, Dupuis J, Hayward C, Psaty B.M, Hall I.P, Parks W.C, Tobin M.D, London S.J. Integrative pathway genomics of lung function and airflow obstruction. Hum Mol Genet. 2015;24(23):6836-6848. DOI: 10.1093/hmg/ddv378

Guerra S, Halonen M, Vasquez M.M, Spangenberg A, Stern D.A, Morgan W.J, Wright A.L, Lavi I, Tarès L, Carsin A.E, Dobano C, Barreiro E, Zock J.P, Martínez-Moratalla J, Urrutia I, Sunyer J, Keidel D, Imboden M, Probst-Hensch N, Hallberg J, Melén E, Wickman M, Bousquet J, Belgrave D.C.M. Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study. Lancet Respir Med. 2015;3(8):613-620. DOI: 10.1016/S2213-2600(15)00196-4

Hampel R, Peters A, Beelen R, Brunekreef B, Cyrys J, de Faire U, de Hoogh K, Fuks K, Hoffmann B, Huls A, Imboden M, Jedynska A, Kooter I, König W, Künzli N, Leander K, Magnussen P, Mannisto S, Penell J, Pershagen G, Phuleria H, Probst-Hensch N, Pundt N, Schaffner E, Schikowski T, Sugiri D, Tittanen P, Tsai M.Y, Wang M, Wolf K, Lanki T. Long-term effects of elemental composition of particulate matter on inflammatory blood markers in European cohorts. Environ Int. 2015;82:76-84. DOI: 10.1016/j.envint.2015.05.008

Imboden M, Kumar A, Curjuric I, Adam M, Thun G.A, Haun M, Tsai M.Y, Pons M, Bettschart R, Turk A, Rochat T, Künzli N, Schindler C, Kronenberg F, Probst-Hensch N.M. Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction analysis. Environ Health Perspect. 2015;123(1):72-79. DOI: 10.1289/ehp.1307398

Jeong A, Imboden M, Schindler C, Probst-Hensch N. Heterogeneity of obesity-asthma association disentangled by latent class analysis. Trop Med Int Health, 2015;20(Suppl. 1):59. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Lanki T, Hampel R, Tiittanen P, Andrich S, Beelen R, Brunekreef B, Dratva J, de Faire U, Fuks K.B, Hoffman B, Imboden M, Jousilahti P, Koenig W, Mahabadi A.A, Künzli N, Pedersen N.L, Penell J, Pershagen G, Probst-Hensch N.M, Schaffner E, Schindler C, Sugiri D, Swart W.J, Tsai M.Y, Turunen A.W, Weinmayr G, Wolf K, Yli-Tuomi T, Peters A. Air pollution from road traffic and systemic inflammation in adults: a cross-sectional analysis in the European ESCAPE project. Environ Health Perspect. 2015;123(8):785-791. DOI: 10.1289/ehp.1408224

Adam M, Imboden M, Boes E, Schaffner E, Künzli N, Phuleria H.C, Kronenberg F, Gaspoz J.M, Carballo D, Probst-Hensch N. Modifying effect of a common polymorphism in the interleukin-6 promoter on the relationship between long-term exposure to traffic-related particulate matter and heart rate variability. PLoS One. 2014;9(8):e104978. DOI: 10.1371/journal.pone.0104978

Curjuric I, Imboden M, Adam M, Bettschart R.W, Gerbase M.W, Künzli N, Rochat T, Rohrer L, Rothe T.B, Schwartz J, Stolz D, Tschopp J.M, Von Eckardstein A, Kronenberg F, Probst-Hensch N.M. Serum bilirubin is associated with lung function in a Swiss general population sample. Eur Respir J. 2014;43(5):1278-1288. DOI: 10.1183/09031936.00055813

Eze I.C, Schaffner E, Fischer E, Schikowski T, Adam M, Imboden M, Tsai M, Carballo D, Von Eckardstein A, Künzli N, Schindler C, Probst-Hensch N. Long-term air pollution exposure and diabetes in a population-based Swiss cohort. Environ Int. 2014;70:95-105. DOI: 10.1016/j.envint.2014.05.014

Mehta A.J, Thun G.A, Imboden M, Ferrarotti I, Keidel D, Künzli N, Kromhout H, Miedinger D, Phuleria H, Rochat T, Russi E.W, Schindler C, Schwartz J, Vermeulen R, Luisetti M, Probst-Hensch N. Interactions between SERPINA1 PiMZ genotype, occupational exposure and lung function decline. Occup Environ Med. 2014;71(4):234-240. DOI: 10.1136/oemed-2013-101592

Scholtens S, Postma D.S, Moffatt M.F, Panasevich S, Granell R, Henderson A.J, Melen E, Nyberg F, Pershagen G, Jarvis D, Ramasamy A, Wjst M, Svanes C, Bouzigon E, Demenais F, Kauffmann F, Siroux V, von Mutius E, Ege M.J, Braun-Fahrländer C, Genuneit J, Brunekreef B, Smit H.A, Wijga A.H, Kerkhof M, Curjuric I, Imboden M, Thun G.A, Probst-Hensch N, Freidin M.B, Bragina E.I, Deev I.A, Puzyrev V.P, Daley D, Park J, Becker A, Chan-Yeung M, Kozyrskyj A.L, Pare P, Marenholn I, Lau S, Keil T, Lee Y.A, Kabesch M, Wijmenga C, Franke L, Nolte I.M, Vonk J, Kumar A, Farrall M, Cookson W.O, Strachan D.P, Koppelman G.H, Boezen H.M. Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure [Letter to the editor]. J Allergy Clin Immunol. 2014;133(3):885-888. DOI: 10.1016/j.jaci.2013.08.049

Siroux V, Gonzalez J.R, Bouzigon E, Curjuric I, Boudier A, Imboden M, Anto J.M, Gut I, Jarvis D, Lathrop M, Omenaas E.R, Pin I, Wjst M, Demenais F, Probst-Hensch N, Kogevinas M, Kauffmann F. Genetic heterogeneity of asthma phenotypes identified by a clustering approach. Eur Respir J. 2014;43(2):439-452. DOI: 10.1183/09031936.00032713

Smit L.A, Strachan D.P, Vermeulen R, de Bakker P.I, Demenais F, Dumas O, Carsin A.E, Cullinan P, Curjuric I, Ghosh R.E, Heederik D, Imboden M, Jarvis D, Lathrop M, Le Moual N, Mehta A, Miedinger D, Sigsgaard T, Siroux V, Vernez D, Zock J.P, Kauffmann F, Probst-Hensch N, Kogevinas M, Bouzigon E. Human leukocyte antigen class II variants and adult-onset asthma: does occupational allergen exposure play a role?. Eur Respir J. 2014;44(5):1234-1242. DOI: 10.1183/09031936.00068014

Smolonska J, Koppelman G.H, Wijmenga C, Vonk J.M, Zanen P, Bruinenberg M, Curjuric I, Imboden M, Thun G.A, Franke L, Probst-Hensch N.M, Nurnberg P, Riemersma R.A, van Schayck C.P, Loth D.W, Brusselle G.G, Stricker B.H, Hofman A, Uitterlinden A.G, Lahousse L, London S.J, Loehr L.R, Manichaikul A, Barr R.G, Donohue K.M, Rich S.S, Pare P, Bosse Y, Hao K, van den Berge M, Groen H.J, Lammers J.W, Mali W, Boezen H.M, Postma D.S. Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis. Eur Respir J. 2014;44(4):860-872. DOI: 10.1183/09031936.00001914

Tang W, Kowgier M, Loth D.W, Soler Artigas M, Joubert B.R, Hodge E, Gharib S.A, Smith A.V, Ruczinski I, Gudnason V, Mathias R.A, Harris T.B, Hansel N.N, Launer L.J, Barnes K.C, Hansen J.G, Albrecht E, Aldrich M.C, Allerhand M, Barr R.G, Brusselle G.G, Couper D.J, Curjuric I, Davies G, Deary I.J, Dupuis J, Fall T, Foy M, Franceschini N, Gao W, Glaser S, Gu X, Hancock D.B, Heinrich J, Hofman A, Imboden M, Ingelsson E, James A, Karrasch S, Koch B, Kritchevsky S.B, Kumar A, Lahousse L, Li G, Lind L, Lindgren C, Liu Y, Lohman K, Lumley T, McArdle W.L, Meibohm B, Morris A.P, Morrison A.C, Musk B, North K.E, Palmer L.J, Probst-Hensch N.M, Psaty B.M, Rivadeneira F, Rotter J.I, Schulz H, Smith L.J, Sood A, Starr J.M, Strachan D.P, Teumer A, Uitterlinden A.G, Völzke H, Voorman A, Wain L.V, Wells M.T, Wilk J.B, Williams O.D, Heckbert S.R, Stricker B.H, London S.J, Fornage M, Tobin M.D, O Connor G.T, Hall I.P, Cassano P.A. Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. PLoS One. 2014;9(7):e100776. DOI: 10.1371/journal.pone.0100776

Thun G.A, Imboden M, Künzli N, Rochat T, Keidel D, Haun M, Schindler C, Kronenberg F, Probst-Hensch N.M. Follow-up on genome-wide main effects: do polymorphisms modify the air pollution effect on lung function decline in adults?. Environ Int. 2014;64:110-115. DOI: 10.1016/j.envint.2013.12.012

Imboden M, Probst-Hensch N.M. Biobanking across the phenome - at the center of chronic disease research. BMC Public Health. 2013;13:1094. DOI: 10.1186/1471-2458-13-1094

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Mélen E, Granell R, Kogevinas M, Strachan D, Gonzalez J.R, Wjst M, Jarvis D, Ege M, Braun-Fahrländer C, Genuneit J, Horak E, Bouzigon E, Demenais F, Kauffmann F, Siroux V, Michel S, von Berg A, Heinzmann A, Kabesch M, Probst-Hensch N.M, Curjuric I, Imboden M, Rochat T, Henderson J, Sterne J.A.C, McArdle W.L, Hui J, James A.L, Musk A.W, Palmer L.J, Becker A, Kozyrskyj A.L, Chan-Young M, Park J.E, Leung A, Daley D, Freidin M.B, Deev I.A, Ogorodova L.M, Puzyrev V.P, Celedón J.C, Brehm J.M, Cloutier M.M, Canino G, Acosta-Pérez E, Soto-Quiros M, Avila L, Bergström A, Magnusson J, Söderhäll C, Kull I, Scholtens S, Boezen H.M, Koppelman G.H, Wijga A.H, Marenholz I, Esparza-Gordillo J, Lau S, Lee Y.A, Standl M, Tiesler C.M.T, Flexeder C, Heinrich J, Myers R.A, Ober C, Nicolae D.L, Farrall M, Kumar A, Moffatt M.F, Cookson W.O.C.M, Lasky-Su J. Genome-wide association study of body mass index in 23,000 individuals with and without asthma. Clin Exp Allergy. 2013;43(4):463-474. DOI: 10.1111/cea.12054

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Thun G.A, Imboden M, Berger W, Rochat T, Probst-Hensch N.M. The association of a variant in the cell cycle control gene CCND1 and obesity on the development of asthma in the Swiss SAPALDIA study. J Asthma. 2013;50(2):147-154. DOI: 10.3109/02770903.2012.757776

Thun G.A, Imboden M, Ferrarotti I, Kumar A, Obeidat M, Zorzetto M, Haun M, Curjuric I, Couto Alves A, Jackson V.E, Albrecht E, Ried J.S, Teumer A, Lopez L.M, Huffman J.E, Enroth S, Bosse Y, Hao K, Timens W, Gyllensten U, Polasek O, Wilson J.F, Rudan I, Hayward C, Sandford A.J, Deary I.J, Koch B, Reischl E, Schulz H, Hui J, James A.L, Rochat T, Russi E.W, Jarvelin M.R, Strachan D.P, Hall I.P, Tobin M.D, Dahl M, Fallgaard Nielsen S, Nordestgaard B.G, Kronenberg F, Luisetti M, Probst-Hensch N.M. Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels. PLoS Genet. 2013;9(8):e1003585. DOI: 10.1371/journal.pgen.1003585

Wüthrich B, Schmid-Grendelmeier P, Schindler C, Imboden M, Bircher A, Zemp E, Probst-Hensch N, SAPALDIA Team. Prevalence of atopy and respiratory allergic diseases in the elderly SAPALDIA population. Int Arch Allergy Immunol. 2013;162(2):143-148. DOI: 10.1159/000351416

Chasman D.I, Fuchsberger C, Pattaro C, Teumer A, Boger C.A, Endlich K, Olden M, Chen M.H, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster M.C, O'Seaghdha C.M, Glazer N, Isaacs A, Liu C.T, Smith A.V, O'Connell J.R, Struchalin M, Tanaka T, Li G, Johnson A.D, Gierman H.J, Feitosa M.F, Hwang S.J, Atkinson E.J, Lohman K, Cornelis M.C, Johansson A, Tonjes A, Dehghan A, Lambert J.C, Holliday E.G, Sorice R, Kutalik Z, Lehtimaki T, Esko T, Deshmukh H, Ulivi S, Chu A.Y, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G, Harris T.B, Launer L.J, Aspelund T, Eiriksdottir G, Mitchell B.D, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra B.A, de Andrade M, Turner S.T, Ding J, Andrews J.S, Freedman B.I, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler H.E, Igl W, Zaboli G, Wild S.H, Wright A.F, Campbell H, Ellinghaus D, Nothlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer H.K, Nauck M, Stracke S, Volker U, Volzke H, Kovacs P, Stumvoll M, Magi R, Hofman A, Uitterlinden A.G, Rivadeneira F, Aulchenko Y.S, Polasek O, Hastie N, Vitart V, Helmer C, Wang J.J, Stengel B, Ruggiero D, Bergmann S, Kahonen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Kramer B.K, Portas L, Ford I, Buckley B.M, Adam M, Thun G.A, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim S.K, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema J.W, Probst-Hensch N.M, Kronenberg F, Toniolo D, Gudnason V, Shuldiner A.R, Coresh J, Schmid R, Ferrucci L, Siscovick D.S, van Duijn C.M, Borecki I.B, Kardia S.L, Liu Y, Curhan G.C, Rudan I, Gyllensten U, Wilson J.F, Franke A, Pramstaller P.P, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker P.M, Parsa A, Bochud M, Heid I.M, Kao W.L, Fox C.S, Kottgen A. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet. 2012;21(24):5329-5343. DOI: 10.1093/hmg/dds369

Conen D, Adam M, Barthelemy J.C, Imboden M, Künzli N, Von Eckardstein A, Rochat T, Gaspoz J.M, Probst-Hensch N, Carballo D. Premature atrial contractions in the general population: prevalence and risk factors. Eur Heart J, 2012;33(Suppl. 1):40

Conen D, Adam M, Roche F, Barthelemy J.C, Felber Dietrich D, Imboden M, Künzli N, Von Eckardstein A, Regenass S, Hornemann T, Rochat T, Gaspoz J.M, Probst-Hensch N, Carballo D. Premature atrial contractions in the general population: frequency and risk factors. Circulation. 2012;126(19):2302-2308. DOI: 10.1161/CIRCULATIONAHA.112.112300

Curjuric I, Imboden M, Nadif R, Kumar A, Liu L.J.S, Phuleria H, Rochat T, Schindler C, Demenais F, Probst-Hensch N.M. Interaction of oxidative stress pathway genes with particulate matter and tobacco smoke on the course of airflow obstruction during 11 years. Genet Epidemiol, 2012;36(2):143

Curjuric I, Imboden M, Nadif R, Kumar A, Schindler C, Haun M, Kronenberg F, Künzli N, Phuleria H, Postma D.S, Russi E.W, Rochat T, Demenais F, Probst-Hensch N.M. Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population. PLoS One. 2012;7(7):e40175. DOI: 10.1371/journal.pone.0040175

Ferrarotti I, Thun G.A, Zorzetto M, Ottaviani S, Imboden M, Schindler C, Von Eckardstein A, Rohrer L, Rochat T, Russi E.W, Probst-Hensch N.M, Luisetti M. Serum levels and genotype distribution of alpha1-antitrypsin in the general population. Thorax. 2012;67(8):669-674. DOI: 10.1136/thoraxjnl-2011-201321

Hancock D.B, Soler Artigas M, Gharib S.A, Henry A, Manichaikul A, Ramasamy A, Loth D.W, Imboden M, Koch B, McArdle W, Smith A.V, Smolonska J, Sood A, Tang W, Wilk J.B, Zhai G, Zhao J.H, Aschard H, Burkart K.M, Curjuric I, Eijgelsheim M, Elliott P, Gu X, Harris T.B, Janson C, Homuth G, Hysi P, Liu J.Z, Loehr L.R, Lohman K, Loos R, Manning A.K, Marciante K.D, Obeidat M, Postma D, Aldrich M, Brusselle G.G, Chen T.H, Eiriksdottir G, Franceschini N, Heinrich J, Rotter J.I, Wijmenga C, Williams O.D, Bentley A.R, Hofman A, Laurie C, Lumley T, Morrison A.C, Joubert B.R, Rivadeneira F, Couper D.J, Kritchevsky S.B, Liu Y, Wjst M, Wain L.V, Vonk J.M, Uitterlinden A, Rochat T, Rich S.S, Psaty B.M, O'Connor G.T, North K.E, Mirel D.B, Meibohm B, Launer L.J, Khaw K.T, Hartikainen A.L, Hammond C.J, Gläser S, Marchini J, Kraft P, Wareham N.J, Völzke H, Stricker B.H.C, Spector T.D, Probst-Hensch N.M, Jarvis D, Jarvelin M.R, Heckbert S.R, Gudnason V, Boezen H.M, Barr R.G, Cassano P.A, Strachan D.P, Fornage M, Hall I.P, Dupuis J, Tobin M.D, London S.J. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet. 2012;8(12):e1003098. DOI: 10.1371/journal.pgen.1003098

Imboden M, Bouzigon E, Curjuric I, Ramasamy A, Kumar A, Hancock D.B, Wilk J.B, Vonk J.M, Thun G.A, Siroux V, Nadif R, Monier F, Gonzalez J.R, Wjst M, Heinrich J, Loehr L.R, Franceschini N, North K.E, Altmüller J, Koppelman G.H, Guerra S, Kronenberg F, Lathrop M, Moffatt M.F, O'Connor G.T, Strachan D.P, Postma D.S, London S.J, Schindler C, Kogevinas M, Kauffmann F, Jarvis D.L, Demenais F, Probst-Hensch N.M. Genome-wide association study of lung function decline in adults with and without asthma. J Allergy Clin Immunol. 2012;129(5):1218-1228. DOI: 10.1016/j.jaci.2012.01.074

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Pattaro C, Kottgen A, Teumer A, Garnaas M, Boger C.A, Fuchsberger C, Olden M, Chen M.H, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster M.C, O'Seaghdha C.M, Glazer N, Isaacs A, Liu C.T, Smith A.V, O'Connell J.R, Struchalin M, Tanaka T, Li G, Johnson A.D, Gierman H.J, Feitosa M, Hwang S.J, Atkinson E.J, Lohman K, Cornelis M.C, Johansson A, Tonjes A, Dehghan A, Chouraki V, Holliday E.G, Sorice R, Kutalik Z, Lehtimaki T, Esko T, Deshmukh H, Ulivi S, Chu A.Y, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G, Harris T.B, Launer L.J, Aspelund T, Eiriksdottir G, Mitchell B.D, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F.B, Demirkan A, Oostra B.A, de Andrade M, Turner S.T, Ding J, Andrews J.S, Freedman B.I, Koenig W, Illig T, Doring A, Wichmann H.E, Kolcic I, Zemunik T, Boban M, Minelli C, Wheeler H.E, Igl W, Zaboli G, Wild S.H, Wright A.F, Campbell H, Ellinghaus D, Nothlings U, Jacobs G, Biffar R, Endlich K, Ernst F, Homuth G, Kroemer H.K, Nauck M, Stracke S, Volker U, Volzke H, Kovacs P, Stumvoll M, Magi R, Hofman A, Uitterlinden A.G, Rivadeneira F, Aulchenko Y.S, Polasek O, Hastie N, Vitart V, Helmer C, Wang J.J, Ruggiero D, Bergmann S, Kahonen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Giulianini F, Kramer B.K, Portas L, Ford I, Buckley B.M, Adam M, Thun G.A, Paulweber B, Haun M, Sala C, Metzger M, Mitchell P, Ciullo M, Kim S.K, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema J.W, Probst-Hensch N.M, Kronenberg F, Toniolo D, Gudnason V, Shuldiner A.R, Coresh J, Schmid R, Ferrucci L, Siscovick D.S, van Duijn C.M, Borecki I, Kardia S.L, Liu Y, Curhan G.C, Rudan I, Gyllensten U, Wilson J.F, Franke A, Pramstaller P.P, Rettig R, Prokopenko I, Witteman J.C, Hayward C, Ridker P, Parsa A, Bochud M, Heid I.M, Goessling W, Chasman D.I, Kao W.H, Fox C.S. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 2012;8(3):e1002584. DOI: 10.1371/journal.pgen.1002584

Thun G.A, Ferrarotti I, Imboden M, Rochat T, Gerbase M, Kronenberg F, Bridevaux P.O, Zemp E, Zorzetto M, Ottaviani S, Russi E.W, Luisetti M, Probst-Hensch N.M. SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort. PLoS One. 2012;7(8):e42728. DOI: 10.1371/journal.pone.0042728

Wilk J.B, Shrine N.R, Loehr L.R, Zhao J.H, Manichaikul A, Lopez L.M, Smith A.V, Heckbert S.R, Smolonska J, Tang W, Loth D.W, Curjuric I, Hui J, Cho M.H, Latourelle J.C, Henry A.P, Aldrich M, Bakke P, Beaty T.H, Bentley A.R, Borecki I.B, Brusselle G.G, Burkart K.M, Chen T.H, Couper D, Crapo J.D, Davies G, Dupuis J, Franceschini N, Gulsvik A, Hancock D.B, Harris T.B, Hofman A, Imboden M, James A.L, Khaw K.T, Lahousse L, Launer L.J, Litonjua A, Liu Y, Lohman K.K, Lomas D.A, Lumley T, Marciante K.D, McArdle W.L, Meibohm B, Morrison A.C, Musk A.W, Myers R.H, North K.E, Postma D.S, Psaty B.M, Rich S.S, Rivadeneira F, Rochat T, Rotter J.I, Soler Artigas M, Starr J.M, Uitterlinden A.G, Wareham N.J, Wijmenga C, Zanen P, Province M.A, Silverman E.K, Deary I.J, Palmer L.J, Cassano P.A, Gudnason V, Barr R.G, Loos R.J, Strachan D.P, London S.J, Boezen H.M, Probst-Hensch N, Gharib S.A, Hall I.P, O'Connor G.T, Tobin M.D, Stricker B.H. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med. 2012;186(7):622-632. DOI: 10.1164/rccm.201202-0366OC

Artigas M.S, Loth D.W, Wain L.V, Gharib S.A, Obeidat M, Tang W, Zhai G, Zhao J.H, Smith A.V, Huffman J.E, Albrecht E, Jackson C.M, Evans D.M, Cadby G, Fornage M, Manichaikul A, Lopez L.M, Johnson T, Aldrich M.C, Aspelund T, Barroso I, Campbell H, Cassano P.A, Couper D.J, Eiriksdottir G, Franceschini N, Garcia M, Gieger C, Gislason G.K, Grkovic I, Hammond C.J, Hancock D.B, Harris T.B, Ramasamy A, Heckbert S.R, Heliovaara M, Homuth G, Hysi P.G, James A.L, Jankovic S, Joubert B.R, Karrasch S, Klopp N, Koch B, Kritchevsky S.B, Launer L.J, Liu Y, Loehr L.R, Lohman K, Loos R.J, Lumley T, Al Balushi K.A, Ang W.Q, Barr R.G, Beilby J, Blakey J.D, Boban M, Boraska V, Brisman J, Britton J.R, Brusselle G.G, Cooper C, Curjuric I, Dahgam S, Deary I.J, Ebrahim S, Eijgelsheim M, Francks C, Gaysina D, Granell R, Gu X, Hankinson J.L, Hardy R, Harris S.E, Henderson J, Henry A, Hingorani A.D, Hofman A, Holt P.G, Hui J, Hunter M.L, Imboden M, Jameson K.A, Kerr S.M, Kolcic I, Kronenberg F, Liu J.Z, Marchini J, McKeever T, Morris A.D, Olin A.C, Porteous D.J, Postma D.S, Rich S.S, Ring S.M, Rivadeneira F, Rochat T, Sayer A.A, Sayers I, Sly P.D, Smith G.D, Sood A, Starr J.M, Uitterlinden A.G, Vonk J.M, Wannamethee S.G, Whincup P.H, Wijmenga C, Williams O.D, Wong A, Mangino M, Marciante K.D, McArdle W.L, Meibohm B, Morrison A.C, North K.E, Omenaas E, Palmer L.J, Pietilainen K.H, Pin I, Pola Sbreve Ek O, Pouta A, Psaty B.M, Hartikainen A.L, Rantanen T, Ripatti S, Rotter J.I, Rudan I, Rudnicka A.R, Schulz H, Shin S.Y, Spector T.D, Surakka I, Vitart V, Volzke H, Wareham N.J, Warrington N.M, Wichmann H.E, Wild S.H, Wilk J.B, Wjst M, Wright A.F, Zgaga L, Zemunik T, Pennell C.E, Nyberg F, Kuh D, Holloway J.W, Boezen H.M, Lawlor D.A, Morris R.W, Probst-Hensch N, Kaprio J, Wilson J.F, Hayward C, Kahonen M, Heinrich J, Musk A.W, Jarvis D.L, Glaser S, Jarvelin M.R, Ch Stricker B.H, Elliott P, O'Connor G.T, Strachan D.P, London S.J, Hall I.P, Gudnason V, Tobin M.D. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet. 2011;43(11):1082-1090. DOI: 10.1038/ng.941

Gerbase M.W, Keidel D, Imboden M, Gemperli A, Bircher A, Schmid-Grendelmeier P, Bridevaux P.O, Berger W, Schindler C, Rochat T, Probst-Hensch N. Effect modification of immunoglobulin E-mediated atopy and rhinitis by glutathione S-transferase genotypes in passive smokers. Clin Exp Allergy. 2011;41(11):1579-1586. DOI: 10.1111/j.1365-2222.2011.03807.x

Imboden M, Bouzigon E, Curjuric I, Ramasamy A, Kumar A, Hancock D.B, Wilk J.B, Vonk J, Strachan D.P, Postma D.S, O'Connor G.T, London S.J, Schindler C, Kogevinas M, Kauffmann F, Jarvis D.L, Demenais F, Probst-Hensch N.M. Genome-wide association study identifies locus determining genetic heterogeneity of lung function decline in asthmatic and non-asthmatic adults. Am J Respir Crit Care Med, 2011;183:A6184

Imboden M, Thun G, Kumar A, Curjuric I, Ferrarotti I, Rochat T, Russi E.W, Luisetti M, Probst-Hensch N.M. Genomewide association with alpha1-antitrypsin blood levels in a subset of the SAPALDIA cohort study. Am J Respir Crit Care Med, 2011;183:A1755

International Consortium for Blood Pressure Genome-Wide Association Studies. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011;478(7367):103-109. DOI: 10.1038/nature10405

London S.J, Hancock D.B, Artigas M.S, Wilk J.B, Loth D, Gharib S, Smith A.V, Imboden M, Tang W, Manichaikul A, Teumer A, Gläser S, Barr R.G, Probst-Hensch N, Harris T, Cassano P.A, O'Connor G.T, Hall I.P, Stricker B.H, Strachan D, Lumley T, Tobin M.D. Genome-wide interaction study with cigarette smoking in relation to pulmonary function. Am J Respir Crit Care Med, 2011;183:A5685

Obeidat M, Wain L.V, Shrine N, Soler Artigas M, Repapi E, Burton P.R, Johnson T, Ramasamy A, Zhao J.H, Zhai G, Huffman J.E, Vitart V, Albrecht E, Igl W, Hartikainen A.L, Pouta A, Cadby G, Hui J, Palmer L.J, Hadley D, McArdle W.L, Rudnicka A.R, Barroso I, Loos R.J.F, Wareham N.J, Mangino M, Soranzo N, Spector T.D, Gläser S, Homuth G, Völzke H, Deloukas P, Granell R, Henderson J, Grkovic I, Jankovic S, Zgaga L, Polasek O, Rudan I, Wright A.F, Campbell H, Wild S.H, Wilson J.F, Heinrich J, Imboden M, Probst-Hensch N.M, Gyllensten U, Johansson A, Zaboli G, Mustelin L, Rantanen T, Surakka I, Kaprio J, Jarvelin M.R, Hayward C, Evans D.M, Koch B, Musk A.W, Elliott P, Strachan D.P, Tobin M.D, Sayers I, Hall I.P, SpiroMeta Consortium. A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS One. 2011;6(5):e19382. DOI: 10.1371/journal.pone.0019382

Ramasamy A, Curjuric I, Coin L.J, Kumar A, McArdle W.L, Imboden M, Leynaert B, Kogevinas M, Schmid-Grendelmeier P, Pekkanen J, Wjst M, Bircher A.J, Sovio U, Rochat T, Hartikainen A.L, Balding D.J, Jarvelin M.R, Probst-Hensch N, Strachan D.P, Jarvis D.L. A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. J Allergy Clin Immunol. 2011;128(5):996-1005. DOI: 10.1016/j.jaci.2011.08.030

Curjuric I, Imboden M, Schindler C, Downs S.H, Hersberger M, Liu L.J, Matyas G, Russi E.W, Schwartz J, Thun G.A, Postma D.S, Rochat T, Probst-Hensch N.M. HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction. Eur Respir J. 2010;35(3):505-514. DOI: 10.1183/09031936.00044309

Hersberger M, Thun G.A, Imboden M, Brandstatter A, Waechter V, Summerer M, Schmid-Grendelmeier P, Bircher A, Rohrer L, Berger W, Russi E.W, Rochat T, Kronenberg F, Probst-Hensch N. Association of STR polymorphisms in CMA1 and IL-4 with asthma and atopy: the SAPALDIA cohort. Hum Immunol. 2010;71(11):1154-1160. DOI: 10.1016/j.humimm.2010.08.008

Köttgen A, Pattaro C, Boger C.A, Fuchsberger C, Olden M, Glazer N.L, Parsa A, Gao X, Yang Q, Smith A.V, O'Connell J.R, Li M, Schmidt H, Tanaka T, Isaacs A, Ketkar S, Hwang S.J, Johnson A.D, Dehghan A, Teumer A, Pare G, Atkinson E.J, Zeller T, Lohman K, Cornelis M.C, Probst-Hensch N.M, Kronenberg F, Tonjes A, Hayward C, Aspelund T, Eiriksdottir G, Launer L.J, Harris T.B, Rampersaud E, Mitchell B.D, Arking D.E, Boerwinkle E, Struchalin M, Cavalieri M, Singleton A, Giallauria F, Metter J, de Boer I.H, Haritunians T, Lumley T, Siscovick D, Psaty B.M, Zillikens M.C, Oostra B.A, Feitosa M, Province M, de Andrade M, Turner S.T, Schillert A, Ziegler A, Wild P.S, Schnabel R.B, Wilde S, Munzel T.F, Leak T.S, Illig T, Klopp N, Meisinger C, Wichmann H.E, Koenig W, Zgaga L, Zemunik T, Kolcic I, Minelli C, Hu F.B, Johansson A, Igl W, Zaboli G, Wild S.H, Wright A.F, Campbell H, Ellinghaus D, Schreiber S, Aulchenko Y.S, Felix J.F, Rivadeneira F, Uitterlinden A.G, Hofman A, Imboden M, Nitsch D, Brandstatter A, Kollerits B, Kedenko L, Magi R, Stumvoll M, Kovacs P, Boban M, Campbell S, Endlich K, Volzke H, Kroemer H.K, Nauck M, Volker U, Polasek O, Vitart V, Badola S, Parker A.N, Ridker P.M, Kardia S.L, Blankenberg S, Liu Y, Curhan G.C, Franke A, Rochat T, Paulweber B, Prokopenko I, Wang W, Gudnason V, Shuldiner A.R, Coresh J, Schmid R, Ferrucci L, Shlipak M.G, van Duijn C.M, Borecki I, Kramer B.K, Rudan I, Gyllensten U, Wilson J.F, Witteman J.C, Pramstaller P.P, Rettig R, Hastie N, Chasman D.I, Kao W.H, Heid I.M, Fox C.S. New loci associated with kidney function and chronic kidney disease. Nat Genet. 2010;42(5):376-384. DOI: 10.1038/ng.568

Moffatt M.F, Gut I.G, Demenais F, Strachan D.P, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson W.O, Imboden M, Liu L.J, Schindler C, Rochat T, Gerbase M, Curjuric I, Thun G.A, Probst-Hensch N, Braun-Fahrländer C. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med. 2010;363(13):1211-1221. DOI: 10.1056/NEJMoa0906312

Repapi E, Sayers I, Wain L.V, Burton P.R, Johnson T, Obeidat M, Zhao J.H, Ramasamy A, Zhai G, Vitart V, Huffman J.E, Igl W, Albrecht E, Deloukas P, Henderson J, Granell R, McArdle W.L, Rudnicka A.R, Barroso I, Loos R.J, Wareham N.J, Mustelin L, Rantanen T, Surakka I, Imboden M, Wichmann H.E, Grkovic I, Jankovic S, Zgaga L, Hartikainen A.L, Peltonen L, Gyllensten U, Johansson A, Zaboli G, Campbell H, Wild S.H, Wilson J.F, Glaser S, Homuth G, Volzke H, Mangino M, Soranzo N, Spector T.D, Polasek O, Rudan I, Wright A.F, Heliövaara M, Ripatti S, Pouta A, Naluai A.T, Olin A.C, Toren K, Cooper M.N, James A.L, Palmer L.J, Hingorani A.D, Wannamethee S.G, Whincup P.H, Smith G.D, Ebrahim S, McKeever T.M, Pavord I.D, MacLeod A.K, Morris A.D, Porteous D.J, Cooper C, Dennison E, Shaheen S, Karrasch S, Schnabel E, Schulz H, Grallert H, Bouatia-Naji N, Delplanque J, Froguel P, Blakey J.D, Britton J.R, Morris R.W, Holloway J.W, Lawlor D.A, Hui J, Nyberg F, Jarvelin M.R, Jackson C, Kahonen M, Kaprio J, Probst-Hensch N.M, Koch B, Hayward C, Evans D.M, Elliott P, Strachan D.P, Hall I.P, Tobin M.D. Genome-wide association study identifies five loci associated with lung function. Nat Genet. 2010;42(1):36-44. DOI: 10.1038/ng.501

Ackermann-Liebrich U, Schindler C, Frei P, Probst-Hensch N.M, Imboden M, Gemperli A, Rochat T, Schmid-Grendelmeier P, Bircher A.J. Sensitisation to Ambrosia in Switzerland: a public health threat on the wait. Swiss Med Wkly. 2009;139(5-6):70-75

Castro-Giner F, Kogevinas M, Imboden M, de Cid R, Jarvis D, Machler M, Berger W, Burney P, Franklin K.A, Gonzalez J.R, Heinrich J, Janson C, Omenaas E, Pin I, Rochat T, Sunyer J, Wjst M, Anto J.M, Estivill X, Probst-Hensch N.M. Joint effect of obesity and TNFA variability on asthma: two international cohort studies. Eur Respir J. 2009;33(5):1003-1009. DOI: 10.1183/09031936.00140608

Imboden M, Schwartz J, Schindler C, Curjuric I, Berger W, Liu L.J.S, Russi E.W, Ackermann-Liebrich U, Rochat T, Probst-Hensch N.M. Decreased PM10 exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect. Environ Health Perspect. 2009;117(9):1420-1427

Imboden M, Rochat T, Brutsche M, Schindler C, Downs S.H, Gerbase M.W, Berger W, Probst-Hensch N.M. Glutathione S-transferase genotype increases risk of progression from bronchial hyperresponsiveness to asthma in adults. Thorax. 2008;63(4):322-328

Probst-Hensch N.M, Imboden M, Felber Dietrich D, Barthelemy J.C, Ackermann-Liebrich U, Berger W, Gaspoz J.M, Schwartz J. Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in nonsmokers. Environ Health Perspect. 2008;116(11):1494-1499

Senn O, Russi E.W, Schindler C, Imboden M, Von Eckardstein A, Brändli O, Zemp E, Ackermann-Liebrich U, Berger W, Rochat T, Luisetti M, Probst-Hensch N.M. Circulating alpha1-antitrypsin in the general population: determinants and association with lung function. Respir Res. 2008;9:35

Zorzetto M, Russi E, Senn O, Imboden M, Ferrarotti I, Tinelli C, Campo I, Ottaviani S, Scabini R, Von Eckardstein A, Berger W, Brändli O, Rochat T, Luisetti M, Probst-Hensch N. SERPINA1 gene variants in individuals from the general population with reduced {alpha}1-antitrypsin concentrations. Clin Chem. 2008;54(8):1331-1338. DOI: 10.1373/clinchem.2007.102798

Imboden M, Downs S.H, Senn O, Matyas G, Brändli O, Russi E.W, Schindler C, Ackermann-Liebrich U, Berger W, Probst-Hensch N.M, SAPALDIA Team. Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study. Respir Res. 2007;8(1):2

Imboden M, Nicod L, Nieters A, Glaus E, Matyas G, Bircher A.J, Ackermann-Liebrich U, Berger W, Probst-Hensch N.M. The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study. Clin Exp Allergy. 2006;36(2):211-218

Imboden M, Nieters A, Bircher A.J, Brutsche M, Becker N, Wjst M, Ackermann-Liebrich U, Berger W, Probst-Hensch N.M, SAPALDIA Team. Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA). Clin Mol Allergy. 2006;4(1):9

Imboden M, Swan H, Denjoy I, Van Langen I.M, Latinen-Forsblom P.J, Napolitano C, Fressart V, Breithardt G, Berthet M, Priori S, Hainque B, Wilde A.A, Schulze-Bahr E, Feingold J, Guicheney P. Female predominance and transmission distortion in the long-QT syndrome. N Engl J Med. 2006;355(26):2744-2751. DOI: 10.1056/NEJMoa042786

Ackermann-Liebrich U, Kuna-Dibbert B, Probst-Hensch N.M, Schindler C, Felber Dietrich D, Zemp Stutz E, Bayer-Oglesby L, Baum F, Brändli O, Brutsche M, Downs S.H, Keidel D, Gerbase M.W, Imboden M, Keller R, Knöpfli B, Künzli N, Nicod L, Pons M, Städele P, Tschopp J.M, Zellweger J.P, Leuenberger P. Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 1991-2003: methods and characterization of participants. Soz Präventivmed. 2005;50(4):245-263

Senn O, Russi E.W, Imboden M, Probst-Hensch N.M. alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants. Eur Respir J. 2005;26(5):909-917

Imboden M, De Saint J.D, Leulier F, Korn H, Goblet C, Bregestovski P. Isolation and characterization of an alpha 2-type zebrafish glycine receptor subunit. Neuroscience. 2001;103(3):799-810

Imboden M, Devignot V, Goblet C. Phylogenetic relationships and chromosomal location of five distinct glycine receptor subunit genes in the teleost Danio rerio. Dev Genes Evol. 2001;211(8-9):415-422. DOI: 10.1007/s004270100164

Imboden M, Devignot V, Korn H, Goblet C. Regional distribution of glycine receptor messenger RNA in the central nervous system of zebrafish. Neuroscience. 2001;103(3):811-830

Martorana M.L, Tawk M, Lapointe T, Barre N, Imboden M, Joulie C, Geraudie J, Vriz S. Zebrafish keratin 8 is expressed at high levels in the epidermis of regenerating caudal fin. Int J Dev Biol. 2001;45(2):449-452

Imboden M, Goblet C, Korn H, Vriz S. Cytokeratin 8 is a suitable epidermal marker during zebrafish development. C R Acad Sci III. 1997;320(9):689-700