Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis (Publications)
Of 2887 travellers between the years 1984-1985, 451 on prophylactic antimalarials were studied retrospectively for adverse haematological or hepatic drug reactions and compared to 296 drug non-users.
Differential infectivity of Plasmodium for mosquitoes (Publications)
The four human malarias - Plasmodium falciparum, P. vivax, P. ovale and P. malariaecan - canonly be transmitted by mosquitoes of the genus Anopheles, although not all species (nor all strains) of thes
Semi-field evaluation of the exposure-free mosquito electrocuting trap and BG-Sentinel trap as an alternative to the human landing catch for measuring... (Publications)
BACKGROUND: The human landing catch (HLC) measures human exposure to mosquito bites and evaluates the efficacy of vector control tools. However, it may expose volunteers to potentially infected mosqui
Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis (Review) (Publications)
Background The World Health Organization (WHO) recommends Xpert MTB/RIF in place of smear microscopy to diagnose tuberculosis (TB), and many countries have adopted it into their diagnostic algorithms.
The effect of community-driven larval source management and house improvement on malaria transmission when added to the standard malaria control... (Publications)
BACKGROUND: Current standard interventions are not universally sufficient for malaria elimination. The effects of community-based house improvement (HI) and larval source management (LSM) as supplemen
A 39-amino-acid C-terminal truncation of GDV1 disrupts sexual commitment in<em> Plasmodium falciparum</em> (Publications)
Malaria is a mosquito-borne disease caused by apicomplexan parasites of the genus Plasmodium. Completion of the parasite's life cycle depends on the transmission of sexual stages, the gametocytes, fro
Antiprotozoal activity of <em>Buxus sempervirens</em> and activity-guided isolation of <em>O</em>-tigloylcyclovirobuxeine-B as the main constituent... (Publications)
Buxus sempervirens L. (European Box, Buxaceae) has been used in ethnomedicine to treat malaria. In the course of our screening of plant extracts for antiprotozoal activity, a CH2Cl2 extract from leave
Malaria mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites (Publications)
BACKGROUND: Malaria continues to be a major cause of infectious disease mortality in tropical regions. However, deaths from malaria are most often not individually documented, and as a result overall
HIV/AIDS-related mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites (Publications)
BACKGROUND: As the HIV/AIDS pandemic has evolved over recent decades, Africa has been the most affected region, even though a large proportion of HIV/AIDS deaths have not been documented at the indivi