Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles (Publications)
Seven novel diamidino 2,5-bis(aryl)thiazoles (5a-g) were synthesized and evaluated against Trypanosoma brucei rhodensiense (T. b. r.) and Plasmodium falciparum (P. f.). The diamidines were obtained di
Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation (Publications)
The synthesis of nine nostocarboline derivatives with substitutions of the 2-methyl group by alkyl, aryl and functionalized residues, 10 symmetrical bis cationic dimers linking 6-Cl-norharmane through
Luftqualität, Lungenkrankheiten und öffentliche Gesundheit (Publications)
In den vergangenen Jahren sind die Auswirkungen der heutigen, durch den motorisierten Verkehr und die Industrie verursachten Luftverschmutzung intensiv untersucht worden. Kurzfristig und langfristig e
Novel inhibitors of <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase with anti-malarial activity in the mouse model (Publications)
Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (