Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from... (Publications)
From the twigs and stems of the Chinese liana Ancistrocladus tectorius (Ancistrocladaceae), two new 5,8'-coupled naphthylisoquinolines, ancistectorine D (5) and its 6-O-demethyl derivative 6, were iso
Efficacy and safety of moxidectin, synriam, synriam-praziquantel <em>versus</em> praziquantel against <em>Schistosoma haematobium</em> and <em>S.... (Publications)
BACKGROUND: Schistosomiasis affects millions of people, yet treatment options are limited. The antimalarial Synriam (piperaquine 150 mg/arterolane 750 mg) and the anthelminthic moxidectin revealed pro
Community perceptions of health and rodent-borne diseases along the Inter-Oceanic Highway in Madre de Dios, Peru (Publications)
BACKGROUND: Madre de Dios is located in the southeastern Amazonian region of Peru. Rodents have been estimated to be the reservoirs for up to 50 % of emerging zoonotic pathogens, including a host of v
Possible healthcare-associated transmission as a cause of secondary infection and population structure of <em>Staphylococcus aureus</em> isolates from... (Publications)
We have previously shown that secondary infections of Buruli ulcer wounds were frequently caused by Staphylococcus aureus. To gain understanding into possible routes of secondary infection, we charact
Acute <em>Gastroenteritis </em>and <em>Campylobacteriosi</em>s in Swiss primary care: the viewpoint of general practitioners (Publications)
Acute gastroenteritis (AG) is frequently caused by infectious intestinal diseases (IID) including food- and waterborne pathogens of public health importance. Among these pathogens, Campylobacter spp.
Prevalence and outcomes of hepatitis B coinfection and associated liver disease among antiretroviral therapy-naive individuals in a rural Tanzanian... (Publications)
Background. We evaluated the prevalence of chronic hepatitis B virus (HBV) infection and liver fibrosis/cirrhosis in human immunodeficiency virus (HIV)-infected individuals enrolled in a rural Tanzani
Approved oncology drugs lack <em>in vivo</em> activity against <em>Trichuris muris</em> despite <em>in vitro</em> activity (Publications)
Infections with soil-transmitted helminths (STHs) are considered among the most persistent global health problems. The few available drugs have limitations including low efficacy against Trichuris tri
Road traffic noise, blood pressure and heart rate: pooled analyses of harmonized data from 88,336 participants (Publications)
INTRODUCTION: Exposure to road traffic noise may increase blood pressure and heart rate. It is unclear to what extent exposure to air pollution may influence this relationship. We investigated associa