Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (Publications)
Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory arthritis. By combining data from > 140,000 individuals of European ancestry within the Global Urate Genetics C
Novel real-time PCR for the universal detection of <em>Strongyloides spp</em> (Publications)
Strongyloidiasis is a neglected disease, which is prevalent mainly in tropical and subtropical regions. It is caused by intestinal nematodes of the genus Strongyloides spp.. Due to rising worldwide tr
Muscle force up to 50% of maximum does not affect cutaneous silent periods in thenar muscles (Publications)
OBJECTIVE: The cutaneous silent period (CSP) is a spinal inhibitory reflex mediated by A-delta fibers. The amount of muscle contraction has been reported to influence CSPs, but this has not been confi
Reduced cardiorespiratory fitness, low physical activity and an urban environment are independently associated with increased cardiovascular risk in... (Publications)
AIMS/HYPOTHESIS: To assist in the development of preventive strategies, we studied whether the neighbourhood environment or modifiable behavioural parameters, including cardiorespiratory fitness (CRF)
Nematode infections: filariases (Publications)
More than 150 million people, mainly in developing countries, are affected by filarial nematode infections that cause debilitating and disfiguring diseases. Although transmission is restricted to the
New loci associated with kidney function and chronic kidney disease (Publications)
Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies have identified common CKD susceptibility variants. The CKDGen consortium performed a meta-analysis of g